scholarly journals Dietary Zinc Intake and Its Association with Metabolic Syndrome Indicators among Chinese Adults: An Analysis of the China Nutritional Transition Cohort Survey 2015

Nutrients ◽  
2018 ◽  
Vol 10 (5) ◽  
pp. 572 ◽  
Author(s):  
Yun Wang ◽  
Xiao-Fang Jia ◽  
Bing Zhang ◽  
Zhi-Hong Wang ◽  
Ji-Guo Zhang ◽  
...  
Author(s):  
Panpan He ◽  
Huan Li ◽  
Mengyi Liu ◽  
Zhuxian Zhang ◽  
Yuanyuan Zhang ◽  
...  

Abstract Aims We aimed to investigate the relationship of dietary zinc intake with new-onset diabetes among Chinese adults. Materials and Methods A total of 16 257 participants who were free of diabetes at baseline from the China Health and Nutrition Survey were included. Dietary intake was measured by 3 consecutive 24-hour dietary recalls combined with a household food inventory. Participants with self-reported physician-diagnosed diabetes, or fasting glucose ≥ 7.0 mmol/L, or glycated hemoglobin ≥ 6.5% during the follow-up were defined as having new-onset diabetes. Results A total of 1097 participants developed new-onset diabetes during a median follow-up duration of 9.0 years. Overall, the association between dietary zinc intake and new-onset diabetes followed a U-shape (P for nonlinearity < 0.001). The risk of new-onset diabetes was significantly lower in participants with zinc intake < 9.1 mg/day (per mg/day: hazard ratio [HR], 0.73; 95% CI, 0.60-0.88), and higher in those with zinc intake ≥ 9.1 mg/day (per mg/day: HR, 1.10; 95% CI, 1.07-1.13). Consistently, when dietary zinc intake was assessed as deciles, compared with those in deciles 2-8 (8.9 -<12.2 mg/day), the risk of new-onset diabetes was higher for decile 1 (<8.9 mg/day: HR, 1.29; 95% CI, 1.04-1.62), and deciles 9 to 10 (≥12.2 mg/day: HR, 1.62; 95% CI, 1.38-1.90). Similar U-shaped relations were found for plant-derived or animal-derived zinc intake with new-onset diabetes (all P for nonlinearity < 0.001). Conclusions There was a U-shaped association between dietary zinc intake and new-onset diabetes in general Chinese adults, with an inflection point at about 9.1 mg/day.


2017 ◽  
Vol 57 (8) ◽  
pp. 2839-2846 ◽  
Author(s):  
Zumin Shi ◽  
Anna Chu ◽  
Shiqi Zhen ◽  
Anne W. Taylor ◽  
Yue Dai ◽  
...  

2013 ◽  
Vol 25 (4) ◽  
pp. 550-554 ◽  
Author(s):  
Milton F. Suarez-Ortegón ◽  
Jenny E. Ordoñez-Betancourth ◽  
Cecilia Aguilar-de Plata

Author(s):  
Hongmei Li ◽  
Qiu Zhang ◽  
Yan He ◽  
Jijun Shi ◽  
Weidong Hu ◽  
...  

2021 ◽  
Vol 49 (1) ◽  
pp. 030006052098631
Author(s):  
Tengfei Yang ◽  
Dongmei Pei

Objective Metabolic syndrome (MetS) involves multiple metabolic disorders and seriously affects human health. Identification of key biological factors associated with MetS incidence is therefore important. We explored the association between MetS and the biochemical profiles of Chinese adults in Shenyang City in a nested case-control study. Methods We included adult participants who underwent physical examination at our hospital for 2 consecutive years. Participants’ biochemical profiles and other MetS components were tested and monitored continuously. Propensity score matching was used to adjust confounding factors between participants with and without MetS. We analyzed the association between incidence of MetS and the biochemical profiles of participants. Results Of 5702 participants who underwent physical examination between 1 January 2017 and 1 December 2018, 538 had confirmed newly developed MetS. After successfully matching 436 pairs of participants, mean cystatin C (Cys-C) level was significantly higher in the MetS group than in the non-MetS group. Logistic regression analysis indicated that age (years) and γ-glutamate transpeptidase, creatinine, uric acid, and Cys-C levels were significantly associated with MetS incidence; among these, the odds ratio of Cys-C was highest (3.03; 95% confidence interval, 1.02–9.00). Conclusions Cys-C levels were significantly associated with the incidence of MetS among Chinese adults.


1985 ◽  
Vol 5 (1) ◽  
pp. 117-122 ◽  
Author(s):  
Charles R. Brown ◽  
Peter J. Bechtel ◽  
Richard M. Forbes ◽  
Raymond S. Vogel

2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Wang-hong Xu ◽  
Xiao-nan Ruan ◽  
Xiao-jin Fu ◽  
Qiu-li Zhu ◽  
Hong Zhang ◽  
...  

2010 ◽  
Vol 12 (3) ◽  
pp. 198-206 ◽  
Author(s):  
Bin Xie ◽  
Paula H. Palmer ◽  
Zengchang Pang ◽  
Ping Sun ◽  
Haiping Duan ◽  
...  

1988 ◽  
Vol 119 (2) ◽  
pp. 174-180 ◽  
Author(s):  
Arshag D. Mooradian ◽  
John E. Morley ◽  
Philip J. Scarpace

Abstract. Zinc deficiency and altered myocardial adenylate cyclase activity commonly occur in diabetes. To determine whether the zinc intake of the animal can account for the altered β-adrenergic receptor activity in the diabetic heart, we determined the β-adrenergic receptor number and isoproterenol-, NaF- and forskolin-stimulated adenylate cyclase activity in diabetic and control rats maintained on low, normal and high zinc diets for 3 weeks. Scatchard analysis of [125I]iodocyanopindolol binding to control heart membrane preparations revealed a binding capacity of 17.3 ± 1.3 fmol/mg protein with a Kd of 35 ± 1.0 pmol/l. Neither the diabetic state nor the zinc status altered these binding parameters. The isoproterenol-stimulated adenylate cyclase acticity was significantly lower in diabetic rats on low zinc diets compared with controls. The NaF- (65.1 ± 5.4 vs 60.8 ± 6.4 pmol cAMP·mg protein−1·min−1) and forskolin-stimulated adenylate cyclase activities (161 ± 9.3 vs 154 ± 21.2 pmol cAMP·mg protein−1· min−1) were not significantly altered in diabetic rats. Low dietary zinc intake compared with high zinc diet significantly increased NaF- and forskolin-stimulated adenylate cyclase activity both in diabetic rats and controls. The effect of dietary zinc content on isoproterenol-stimulated adenylate cyclase was significant in control rats only. Thus zinc intake appears to be an important determinant of cardiac adenylate cyclase activity level. Additional factors peculiar to the diabetic state are involved in the modulation of β-adrenergic responsiveness of the diabetic heart.


Sign in / Sign up

Export Citation Format

Share Document