Faculty Opinions recommendation of Migration and function of a glial subtype in the vertebrate peripheral nervous system.

2002 ◽  
Author(s):  
Andrew Lumsden
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
And Function

The Peripheral Nervous System: Anatomy and Function

2012 ◽  
pp. 1-67
Author(s):  
Rolfe Birch ◽  
Rolfe Birch ◽  
Rolfe Birch ◽  
Rolfe Birch
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
And Function

scholarly journals The origin, fate and function of macrophages in the peripheral nervous system—an update

2020 ◽  
Vol 32 (11) ◽  
pp. 709-717 ◽  
Author(s):  
Lukas Amann ◽  
Marco Prinz
Keyword(s):  
Gene Expression ◽  
Nervous System ◽  
Rna Sequencing ◽  
Peripheral Nervous System ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
New Techniques ◽  
Macrophage Populations ◽  
And Function ◽  
First Time

Abstract The field of macrophage biology has made enormous progress over recent years. This was triggered by the advent of several new techniques such as the establishment of Cre/loxP-based transgenic mouse models that allowed for the first time delineation of the ontogeny and function of specific macrophage populations across many tissues. In addition, the introduction of new high-throughput technologies like bulk RNA sequencing and later single-cell RNA sequencing as well as advances in epigenetic analysis have helped to establish gene expression profiles, enhancer landscapes and local signaling cues that define and shape the identity of diverse macrophage populations. Nonetheless, some macrophage populations, like the ones residing in the peripheral nervous system (PNS), have not been studied in such detail yet. Here, we discuss recent studies that shed new light on the ontogeny, heterogeneity and gene expression profiles of resident macrophages in peripheral nerves and described differential activation of macrophage subsets during and after acute sciatic nerve injury.

scholarly journals Expression and function of aquaporins in peripheral nervous system

2011 ◽  
Vol 32 (6) ◽  
pp. 711-715 ◽  
Author(s):  
Tong-hui Ma ◽  
Hong-wen Gao ◽  
Xue-dong Fang ◽  
Hong Yang
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
And Function

scholarly journals S100A4 in the Physiology and Pathology of the Central and Peripheral Nervous System

Cells ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 798
Author(s):  
Nadia D’Ambrosi ◽  
Martina Milani ◽  
Savina Apolloni
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
Cell Communication ◽  
Large Family ◽  
Limited Information ◽  
Cellular Motility ◽  
Acute Injuries ◽  
Synovial Tissues ◽  
And Function ◽  
Inflammatory Phenotypes

S100A4 is a member of the large family of S100 proteins, exerting a broad range of intracellular and extracellular functions that vary upon different cellular contexts. While S100A4 has long been implicated mainly in tumorigenesis and metastatization, mounting evidence shows that S100A4 is a key player in promoting pro-inflammatory phenotypes and organ pro-fibrotic pathways in the liver, kidney, lung, heart, tendons, and synovial tissues. Regarding the nervous system, there is still limited information concerning S100A4 presence and function. It was observed that S100A4 exerts physiological roles contributing to neurogenesis, cellular motility and chemotaxis, cell differentiation, and cell-to cell communication. Furthermore, S100A4 is likely to participate to numerous pathological processes of the nervous system by affecting the functions of astrocytes, microglia, infiltrating cells and neurons and thereby modulating inflammation and immune reactions, fibrosis as well as neuronal plasticity and survival. This review summarizes the current state of knowledge concerning the localization, deregulation, and possible functions of S100A4 in the physiology of the central and peripheral nervous system. Furthermore, we highlight S100A4 as a gene involved in the pathogenesis of neurological disorders such as brain tumors, neurodegenerative diseases, and acute injuries.

scholarly journals Migration and Function of a Glial Subtype in the Vertebrate Peripheral Nervous System

Neuron ◽  
2002 ◽  
Vol 34 (4) ◽  
pp. 577-588 ◽  
Author(s):  
Darren T. Gilmour ◽  
Hans-Martin Maischein ◽  
Christiane Nüsslein-Volhard
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
And Function

Neuroembryology and Development of the Nervous System

2017 ◽  
pp. 9-46
Author(s):  
Eduardo E. Benarroch ◽  
Jeremy K. Cutsforth-Gregory ◽  
Kelly D. Flemming
Keyword(s):  
Spinal Cord ◽  
Nervous System ◽  
Embryonic Development ◽  
Peripheral Nervous System ◽  
System P ◽  
And Function ◽  
The Brain

The study of neuroscience begins with a survey of the embryonic development of the nervous system because it provides a framework and background for understanding the anatomy and function of the nervous system in the adult. The eventual location and connectivity of the structures in the brain, spinal cord, and peripheral nervous system reflect the orderly development of the nervous system.

scholarly journals Battery-free, fully implantable optofluidic cuff system for wireless optogenetic and pharmacological neuromodulation of peripheral nerves

2019 ◽  
Vol 5 (7) ◽  
pp. eaaw5296 ◽  
Author(s):  
Yi Zhang ◽  
Aaron D. Mickle ◽  
Philipp Gutruf ◽  
Lisa A. McIlvried ◽  
Hexia Guo ◽  
...  
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
Peripheral Nerves ◽  
Light Emitting Diode ◽  
Microfluidic System ◽  
Neuronal Function ◽  
Pharmacological Agents ◽  
Light Emitting ◽  
And Function

Studies of the peripheral nervous system rely on controlled manipulation of neuronal function with pharmacologic and/or optogenetic techniques. Traditional hardware for these purposes can cause notable damage to fragile nerve tissues, create irritation at the biotic/abiotic interface, and alter the natural behaviors of animals. Here, we present a wireless, battery-free device that integrates a microscale inorganic light-emitting diode and an ultralow-power microfluidic system with an electrochemical pumping mechanism in a soft platform that can be mounted onto target peripheral nerves for programmed delivery of light and/or pharmacological agents in freely moving animals. Biocompliant designs lead to minimal effects on overall nerve health and function, even with chronic use in vivo. The small size and light weight construction allow for deployment as fully implantable devices in mice. These features create opportunities for studies of the peripheral nervous system outside of the scope of those possible with existing technologies.

scholarly journals IDENTIFIKASI MISKONSEPSI SISTEM SARAF PADA BUKU TEKS BIOLOGI KELAS XI

2017 ◽  
Vol 3 (1) ◽  
pp. 39
Author(s):  
Irma Hidayati ◽  
Abdullah , ◽  
Mustafa Sabri
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Peripheral Nervous System ◽  
Structure And Function ◽  
National Education ◽  
Biology Textbooks ◽  
And Function ◽  
Nerve System

This study entitled “Identifying the misconceptions in nervous system in12th Grade of biology textbook” aims to identify misconception on biology textbooks’ about nervous system. The method of the research was descriptive. The objects of the research were 7 of biology textbooks for grade xi published within the last 5 years. The national education regulation no. 1 year 2011, 4 january 2011 states that the textbook used at school should be at least in the last 5 years. The instrument used were observation sheet to compare the concept of the investigated book to the foreign source textbook as guidance. The results showed that there were misconceptions in the material of nerve system contained in 7 textbooks investigated, they were in the concept of structure and function of nervous, impuls, central nervous system and peripheral nervous system.

Glucuronyl 3-sulfate occurs exclusively on distal unmyelinated terminals of selected sensory neurons in the peripheral nervous system

1995 ◽  
Vol 53 ◽  
pp. 958-959
Author(s):  
S.S. Spicer ◽  
B.A. Schulte
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cerebral Cortex ◽  
Peripheral Nervous System ◽  
Sensory Neurons ◽  
Sensory Nerves ◽  
Tissue Antigens ◽  
The Central Nervous System ◽  
The Brain ◽  
Leu 7

Generation of monoclonal antibodies (MAbs) against tissue antigens has yielded several (VC1.1, HNK- 1, L2, 4F4 and anti-leu 7) which recognize the unique sugar epitope, glucuronyl 3-sulfate (Glc A3- SO4). In the central nervous system, these MAbs have demonstrated Glc A3-SO4 at the surface of neurons in the cerebral cortex, the cerebellum, the retina and other widespread regions of the brain.Here we describe the distribution of Glc A3-SO4 in the peripheral nervous system as determined by immunostaining with a MAb (VC 1.1) developed against antigen in the cat visual cortex. Outside the central nervous system, immunoreactivity was observed only in peripheral terminals of selected sensory nerves conducting transduction signals for touch, hearing, balance and taste. On the glassy membrane of the sinus hair in murine nasal skin, just deep to the ringwurt, VC 1.1 delineated an intensely stained, plaque-like area (Fig. 1). This previously unrecognized structure of the nasal vibrissae presumably serves as a tactile end organ and to our knowledge is not demonstrable by means other than its selective immunopositivity with VC1.1 and its appearance as a densely fibrillar area in H&E stained sections.

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