Faculty Opinions recommendation of Genetic analysis of interactions between the somitic muscle, cartilage and tendon cell lineages during mouse development.

2005 ◽  
Author(s):  
Patrick Tam
Keyword(s):  
Genetic Analysis ◽  
Mouse Development ◽  
Tendon Cell ◽  
Cell Lineages

Molecular genetic analysis of glucocorticoid signaling during mouse development

Steroids ◽  
1995 ◽  
Vol 60 (1) ◽  
pp. 93-96 ◽  
Author(s):  
Timothy J. Cole ◽  
Julie A. Blendy ◽  
A.Paula Monaghan ◽  
Wolfgang Schmid ◽  
Adriano Aguzzi ◽  
...  
Keyword(s):  
Genetic Analysis ◽  
Molecular Genetic ◽  
Molecular Genetic Analysis ◽  
Mouse Development ◽  
Glucocorticoid Signaling

scholarly journals MITOCHONDRIAL GENETIC ANALYSIS BY ZYGOTE CELL LINEAGES IN SACCHAROMYCES CEREVISIAE

Genetics ◽  
1973 ◽  
Vol 73 (3) ◽  
pp. 367-377
Author(s):  
D Wilkie ◽  
D Y Thomas
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Genetic Analysis ◽  
Pedigree Analysis ◽  
Cell Lineages ◽  
Mitochondrial Markers ◽  
Yeast Strains ◽  
Oligomycin A ◽  
Multiple Recombination

ABSTRACT Yeast strains were constructed carrying multiple mitochondrial markers conferring resistance to the inhibitors erythromycin, chloramphenicol, paromomycin and oligomycin. A pedigree analysis of two crosses was made by micromanipulating buds from zygotes. The first few daughter buds isolated from the zygotes sometimes gave rise to diploid clones which had a mixture of mitochondrial types. All possible classes of mitochondrial parental and recombinant types were found although they never appeared all together as the progeny from a single zygote. It was inferred that multiple recombination events took place in zygotes and in some of the buds derived from them. After removal of the first four or so daughter buds, subsequent buds from the zygote carried one mitochondrial type only. In cross I in which three markers were analyzed this was most frequently one of the parental types. In cross II (involving four mitochondrial markers) the later buds from the zygotes were frequently of recombinant mitochondrial type.

Genetic analysis of developmental mechanisms in hydra. VI. Cellular composition of chimera hydra

1979 ◽  
Vol 35 (1) ◽  
pp. 1-15
Author(s):  
T. Sugiyama ◽  
T. Fujisawa
Keyword(s):  
Epithelial Cell ◽  
Genetic Analysis ◽  
Interstitial Cell ◽  
Cell Types ◽  
Interstitial Cells ◽  
Cellular Composition ◽  
Feedback Mechanisms ◽  
Cell Lineages ◽  
Developmental Mechanisms ◽  
Homeostatic Mechanisms

The homeostatic mechanisms that maintain constant cellular ratios in hydra tissue were studied using mutant and chimeric hydra strains. Mutants having abnormal cellular compositions are isolated through sexual inbreeding of wild hydra, as described in previous papers of this series. Chimeric hydra are produced by making use of a strain (nf-I) which lacks interstitial cells, nerve cells and nematocytes in its tissue. Reintroduction of interstitial cells from other strains (both normal and mutant) into nf-I leads to creation of chimeric strains having epithelial cell lineages from one strain (nf-I) and interstitial cell lineages from others. Analyses and comparisons of the cellular compositions of all these strains revealed that the numbers of nerve or interstitial cells in the chimeras were very similar to (statistically significantly correlated with) those in their interstitial cell donors. Since chimeras and their interstitial cell donors share the same interstitial cell lineages, this suggests that interstitial cells or their derivatives (nerves and nematocytes) play major roles in determining the nerve and interstitial cell levels in the hydra tissue. It is suggested that some form of homeostatic feedback mechanisms are probably involved in regulating the levels of these cell types.

scholarly journals Genetic analysis of specific and redundant roles for p38  and p38  MAPKs during mouse development

2011 ◽  
Vol 108 (31) ◽  
pp. 12764-12769 ◽  
Author(s):  
I. del Barco Barrantes ◽  
J. M. Coya ◽  
F. Maina ◽  
J. S. C. Arthur ◽  
A. R. Nebreda
Keyword(s):  
Genetic Analysis ◽  
Mouse Development ◽  
P38 Mapks

The genetic analysis of cell lineage in Caenorhabditis elegans

1985 ◽  
Vol 312 (1153) ◽  
pp. 129-137 ◽  
Keyword(s):  
Caenorhabditis Elegans ◽  
Genetic Analysis ◽  
Genetic Control ◽  
Cell Lineage ◽  
Cell Lineages ◽  
Genetic Programme

The genetic control of cell lineage has been studied extensively in Caenorhabditis elegans . In this paper, three studies of cell lineage mutants are reviewed: the isolation of mutations affecting vulval cell lineages, and the analysis of two ‘control genes’, lin -12 and lin -14. In addition, certain logical features of the genetic programme, as inferred from or illuminated by the study of cell lineage mutants, are discussed: the concepts of ‘ control genes ’ and developmental subprogrammes, and the organization of the lineage into a hierarchy of binary decisions.

Molecular genetic analysis of Wnt signals in mouse development

1995 ◽  
Vol 6 (4) ◽  
pp. 267-274 ◽  
Author(s):  
Scott M.K. Lee ◽  
Mary E. Dickinson ◽  
Brian A. Parr ◽  
Seppo Vainio ◽  
Andrew P. McMahon
Keyword(s):  
Genetic Analysis ◽  
Molecular Genetic ◽  
Molecular Genetic Analysis ◽  
Mouse Development
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