Faculty Opinions recommendation of Predicting outcome after lung resection for invasive pulmonary aspergillosis in patients with neutropenia.

2006 ◽  
Author(s):  
Roxana Vitale
Keyword(s):  
Lung Resection ◽  
Invasive Pulmonary Aspergillosis ◽  
Pulmonary Aspergillosis ◽  
Predicting Outcome

Predicting Outcome After Lung Resection for Invasive Pulmonary Aspergillosis in Patients With Neutropenia

CHEST Journal ◽  
2004 ◽  
Vol 126 (6) ◽  
pp. 1783-1788 ◽  
Author(s):  
Peter Matt ◽  
Franziska Bernet ◽  
James Habicht ◽  
Franco Gambazzi ◽  
Alois Gratwohl ◽  
...  
Keyword(s):  
Lung Resection ◽  
Invasive Pulmonary Aspergillosis ◽  
Pulmonary Aspergillosis ◽  
Predicting Outcome

scholarly journals Aspergilloma Superimposed Infection on Lymphoid Interstitial Pneumonia

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Daniel Tran ◽  
Rajagopalan Rengan ◽  
James Lee ◽  
Alan Lucerna ◽  
James Espinosa
Keyword(s):  
Lung Disease ◽  
Interstitial Pneumonia ◽  
Opportunistic Infections ◽  
Lung Resection ◽  
Invasive Pulmonary Aspergillosis ◽  
Pulmonary Aspergillosis ◽  
Cystic Lung ◽  
Cystic Lung Disease ◽  
Interstitial Disease ◽  
Immunodeficiency Syndromes

We describe a case of a 27-year-old female without any prior underlying immunodeficiency syndromes who presented with hemoptysis secondary to subacute invasive pulmonary aspergillosis and subsequently diagnosed with lymphoid interstitial pneumonia (LIP). CT chest demonstrated bilateral interstitial disease with patchy opacities and multiple large cysts and bullae. Diagnosis was confirmed histologically after surgical lung resection of the mycetoma containing cavitation. Therefore, LIP should be suspected in patients presenting with opportunistic infections in the setting of cystic lung disease.

Thoracoscopic Lingulectomy for Invasive Pulmonary Aspergillosis

2007 ◽  
Vol 73 (3) ◽  
pp. 279-280 ◽  
Author(s):  
Bryan A. Whitson ◽  
Michael A. Maddaus ◽  
Rafael S. Andrade
Keyword(s):  
Acute Myeloid Leukemia ◽  
Mortality Rate ◽  
Myeloid Leukemia ◽  
Immunocompromised Patient ◽  
Lung Resection ◽  
Invasive Pulmonary Aspergillosis ◽  
Immunocompromised Patients ◽  
Anatomic Resection ◽  
Pulmonary Aspergillosis ◽  
Acute Myeloid

Invasive pulmonary aspergillosis (IPA) is associated with a high mortality rate in immunocompromised patients. Surgery has a therapeutic role for selected patients when the main objective is to achieve infection control with minimal lung resection. Large or deep-seated lesions may require an anatomic resection such as segmentectomy, lobectomy, or pneumonectomy. Thoracoscopic lobectomy has been described as a treatment of localized IPA; however, thoracoscopic anatomic segmentectomy has not been reported until now. Herein, we describe a case of thoracoscopic lingulectomy for localized IPA in an immunocompromised patient: this operation minimized the delay in resuming therapy for the patient's underlying acute myeloid leukemia. Video-assisted thoracoscopic segmentectomy can be safely performed for localized IPA.

Lung Resection for Invasive Pulmonary Aspergillosis in Neutropenic Patients with Hematologic Malignancies: Long Term Results in Thirty Two Cases.

Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 2857-2857 ◽  
Author(s):  
Thomas Gastinne ◽  
Cyril Touzeau ◽  
Stéphane Vigouroux ◽  
Steven Le Gouill ◽  
Béatrice Mahé ◽  
...  
Keyword(s):  
Surgical Resection ◽  
Antifungal Therapy ◽  
Lung Resection ◽  
Invasive Pulmonary Aspergillosis ◽  
Long Term Results ◽  
High Dose ◽  
Cell Transplant ◽  
Intensive Chemotherapy ◽  
Pulmonary Aspergillosis ◽  
Neutropenic Patients

Abstract Invasive pulmonary aspergillosis (IPA) is a major cause of morbidity and mortality in neutropenic patients. Despite adequate medical treatments, such as amphotericin B or voriconazole, the prognosis of IPA remains poor. Nevertheless, recent studies suggest that the outcome of IPA is improving due to early diagnosis (CT scan, antigenemia), use of new antifungal agents (Azols and Echinocandins), and possibly in some cases to early surgical resection. We here report a retrospective one center study of 32 cases of IPA treated by surgical treatment from 1988 to 2005. Between 1988 and December 2005, thirty-seven consecutive patients underwent lung resection for suspected IPA. They were 22 men and 15 women, with a median age of 49.2 years (15 – 74). The underlying diseases were AML, ALL, aggressive lymphoma and myeloma in 26, 7, 2 and 2 cases, respectively. Surgery was planned after hematologic recovery from the last course of chemotherapy during which IPA was diagnosed, either possible in 18 cases, probable in 18 cases or proven in 1 case (Ascioglu, CID 2002). Surgery consisted in 1 pneumectomy, 6 bilobectomies, 18 lobectomies, 8 wedge resections and 4 lobectomies with wedge resections. No perioperative deaths occurred and the median duration of post surgical hospitalisation was 13 days. Six patients presented surgery related complications: three patients required prolonged pleural drainage, one had a section of the phrenic nerve, one presented a major bleeding and last patient had a pneumopathy. The diagnosis of definite IPA was confirmed in 32 cases. Immediately after surgery, 26 of the 32 patients were able to receive subsequent intensive chemotherapy courses, including 15 stem cell transplant (SCT), either auto (5) or allogenic (10). In all cases, patients subsequently received parenteral antifungal therapy. During these new intensive chemotherapy courses, recurrent aspergillosis was observed in only 2 cases, inducing 1 death from brain localization. Overall, with a median follow-up of 8.3 years (1–18), 40.5% of the patients are alive and the main cause of mortality was relapse, but not IPA. In conclusion, early surgical resection together with antifungal therapy allows definite diagnosis of IPA, prevents from IPA recurrence and early death due to hemotysis, with very few peri-operative complications. All the more, it allows subsequent high-dose chemotherapy to treat the underlying hematologic disease. Surgery might be a treatment of choice to a define group of patient.

scholarly journals Lung resection in a patient with invasive pulmonary aspergillosis after intensive chemotherapy for leukemia

2010 ◽  
Vol 24 (6) ◽  
pp. 945-9448
Author(s):  
Yuichi Sakairi ◽  
Chikabumi Kadoyama ◽  
Hironobu Wada ◽  
Yoshito Yamada ◽  
Ichiro Yoshino
Keyword(s):  
Lung Resection ◽  
Invasive Pulmonary Aspergillosis ◽  
Intensive Chemotherapy ◽  
Pulmonary Aspergillosis

Lung Resection for Invasive Pulmonary Aspergillosis in Neutropenic Patients with Hematologic Diseases

1998 ◽  
Vol 158 (3) ◽  
pp. 885-890 ◽  
Author(s):  
FRANK REICHENBERGER ◽  
JAMES HABICHT ◽  
ACHIM KAIM ◽  
PETER DALQUEN ◽  
FRANZISKA BERNET ◽  
...  
Keyword(s):  
Lung Resection ◽  
Invasive Pulmonary Aspergillosis ◽  
Pulmonary Aspergillosis ◽  
Hematologic Diseases ◽  
Neutropenic Patients

Translational immunoPET/MR imaging of invasive pulmonary aspergillosis

2019 ◽  
Author(s):  
J Schwenck ◽  
N Beziere ◽  
A Maurer ◽  
AM Wild ◽  
H Henneberg ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Invasive Pulmonary Aspergillosis ◽  
Pulmonary Aspergillosis
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