Faculty Opinions recommendation of Persistence of antibody response following a booster dose of Hib-MenC-TT glycoconjugate vaccine to five years: a follow-up study.

2012 ◽  
Author(s):  
Susan Coffin
Keyword(s):  
Antibody Response ◽  
Booster Dose ◽  
Follow Up Study ◽  
Glycoconjugate Vaccine

scholarly journals Dynamics of Antibody Response to BNT162b2 mRNA COVID-19 Vaccine: A 7-Month Follow-Up Study

Medicina ◽  
2021 ◽  
Vol 57 (12) ◽  
pp. 1330
Author(s):  
Tudor Rares Olariu ◽  
Sorin Ursoniu ◽  
Iosif Marincu ◽  
Maria Alina Lupu
Keyword(s):  
Immune Responses ◽  
Antibody Response ◽  
Healthcare Workers ◽  
Booster Dose ◽  
Time Points ◽  
Follow Up Study ◽  
Previous Infection ◽  
Chemiluminescent Microparticle Immunoassay ◽  
Study Participants

Background and Objectives: Comprehension regarding immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is limited, and the durability of immune responses after vaccination is currently unknown. Several studies have reported on the antibody response in fully vaccinated individuals with a limited follow-up of the participants, i.e., below 7 months. Materials and Methods: The antibody response to complete vaccination with the BNT162b2 mRNA COVID-19 vaccine was assessed monthly, for 7 months, in 92 healthcare workers, between February 26 and September 26, 2021. The SARS-CoV-2 anti-spike protein IgG (IgGS) antibody was detected using the SARS-CoV-2 IgG II Quant assay (Abbott, Diagnostics Division, Sligo, Ireland), a chemiluminescent microparticle immunoassay (CMIA) with a sensitivity of 98.1% and specificity of 99.6%. Participants were divided into two groups, one for individuals previously infected with SARS-CoV-2 and the other for individuals without previous infection. Results: The median IgGS titers decreased monthly both in previously infected individuals and in the uninfected group. Previously infected individuals had significantly higher median titers of IgGS compared with previously uninfected subjects at all seven time points after complete vaccination (p < 0.001). Conclusions: Seven months after vaccination, the median IgGS titer had decreased by more than 92% both in individuals previously infected with SARS-CoV-2 and in uninfected individuals. However, IgGS antibodies were still detected in all study participants and persisted throughout the 7 months after the second dose of the vaccine. Further studies should be conducted to monitor the antibody response to the BNT162b2 mRNA vaccine beyond 7 months, to assess the need for a new booster dose in order to extend the duration and amplitude of the specific immune response.

Persistence of Antibody Response Following a Booster Dose of Hib-MenC-TT Glycoconjugate Vaccine to Five Years

2012 ◽  
pp. 1
Author(s):  
Ameneh Khatami ◽  
Matthew D. Snape ◽  
Jacek Wysocki ◽  
Tessa M. John ◽  
Sharon Westcar ◽  
...  
Keyword(s):  
Antibody Response ◽  
Booster Dose ◽  
Glycoconjugate Vaccine

scholarly journals A follow-up study of the human class and subclass antibody response developed against the adult stage ofTrichinella spiralis

Parasite ◽  
2001 ◽  
Vol 8 ◽  
pp. S163-S167 ◽  
Author(s):  
M.R. Chapa-Ruiz ◽  
D. González-Pantaleón ◽  
A. Morales-Galán ◽  
A. Contreras-Ramos ◽  
M. Salinas-Tobón ◽  
...  
Keyword(s):  
Antibody Response ◽  
Adult Stage ◽  
Human Class ◽  
Follow Up Study

scholarly journals Persisting Antibody Response to SARS-CoV-2 in a Local Austrian Population

2021 ◽  
Vol 8 ◽  
Author(s):  
Dennis Ladage ◽  
Delia Rösgen ◽  
Clemens Schreiner ◽  
Dorothee Ladage ◽  
Christoph Adler ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Antibody Response ◽  
Igg Antibodies ◽  
Specific Antibodies ◽  
Follow Up Study ◽  
Population Immunity ◽  
Global Pandemic ◽  
Iga Antibodies ◽  
Austrian Population

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic recently. The prevalence and persistence of antibodies following a peak SARS-CoV-2 infection provides insights into the potential for some level of population immunity. In June 2020, we succeeded in testing almost half of the population of an Austrian town with a higher incidence of COVID-19 infection. We performed a follow-up study to reassess the prevalence of SARS-CoV-2-specific IgA and IgG antibodies with 68 participants of the previous study. We found that the prevalence of IgG or IgA antibodies remained remarkably stable, with 84% of our cohort prevailing SARS-CoV-2-specific antibodies (only a slight decrease from 93% 4 months before). In most patients with confirmed COVID-19 seroconversion potentially provides immunity to reinfection. Our results suggest a stable antibody response observed for at least 6 months post-infection with implications for developing strategies for testing and protecting the population.

scholarly journals Persisting antibody response to SARS-CoV-2 in a local Austrian population

2020 ◽  
Author(s):  
Dennis Ladage ◽  
Delia Rösgen ◽  
Clemens Schreiner ◽  
Dorothee Ladage ◽  
Christoph Adler ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Antibody Response ◽  
Igg Antibodies ◽  
Specific Antibodies ◽  
Follow Up Study ◽  
Population Immunity ◽  
Global Pandemic ◽  
Iga Antibodies ◽  
Austrian Population

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. The prevalence and persistence of antibodies following a peak SARS-CoV-2 infection provides insights into the potential for some level of population immunity. In June 2020 we succeeded in testing almost half of the population of an Austrian township with a higher incidence for COVID-19 infections. Now we performed a follow-up study to reassess the prevalence of SARS-CoV-2-specific IgA and IgG antibodies. In 121 people, including 68 participants of the previous study we found the prevalence of IgG and IgA antibodies remaining remarkably stable with 84% of our cohort prevailing SARS-CoV-2-specific antibodies, which is only a slight decrease from 93% four months before. Most patients with confirmed COVID-19 seroconvert, potentially providing immunity to reinfection. Our results suggest a stable antibody response that we observed for at least six months post infection with implications for developing strategies for testing and protecting the population.

scholarly journals Antibody Levels and Protection after Hepatitis B Vaccine: Results of a 22‐Year Follow‐Up Study and Response to a Booster Dose

2009 ◽  
Vol 200 (9) ◽  
pp. 1390-1396 ◽  
Author(s):  
Brian J. McMahon ◽  
Catherine M. Dentinger ◽  
Dana Bruden ◽  
Carolyn Zanis ◽  
Helen Peters ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Booster Dose ◽  
Hepatitis B Vaccine ◽  
Follow Up Study ◽  
Antibody Levels

scholarly journals Antibody Levels and Protection After Hepatitis B Vaccine: Results of a 30-Year Follow-up Study and Response to a Booster Dose

2016 ◽  
Vol 214 (1) ◽  
pp. 16-22 ◽  
Author(s):  
Michael G. Bruce ◽  
Dana Bruden ◽  
Debby Hurlburt ◽  
Carolyn Zanis ◽  
Gail Thompson ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Booster Dose ◽  
Hepatitis B Vaccine ◽  
Follow Up Study ◽  
Antibody Levels

Electron Microscopy of Human Gallstones

1971 ◽  
Vol 29 ◽  
pp. 296-297
Author(s):  
C. Wolpers ◽  
R. Blaschke
Keyword(s):  
Electron Microscopy ◽  
Room Temperature ◽  
Bile Pigment ◽  
X Ray Diffraction ◽  
Triclinic Crystal System ◽  
X Ray ◽  
Follow Up Study ◽  
Infra Red ◽  
Main Components

Scanning microscopy was used to study the surface of human gallstones and the surface of fractures. The specimens were obtained by operation, washed with water, dried at room temperature and shadowcasted with carbon and aluminum. Most of the specimens belong to patients from a series of X-ray follow-up study, examined during the last twenty years. So it was possible to evaluate approximately the age of these gallstones and to get information on the intensity of growing and solving.Cholesterol, a group of bile pigment substances and different salts of calcium, are the main components of human gallstones. By X-ray diffraction technique, infra-red spectroscopy and by chemical analysis it was demonstrated that all three components can be found in any gallstone. In the presence of water cholesterol crystallizes in pane-like plates of the triclinic crystal system.

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