scholarly journals Faculty Opinions recommendation of Dynamic Formation of Microvillus Inclusions During Enterocyte Differentiation in Munc18-2-Deficient Intestinal Organoids.

2019 ◽  
Author(s):  
Ravinder Gill
Keyword(s):  
Intestinal Organoids ◽  
Enterocyte Differentiation ◽  
Dynamic Formation

scholarly journals Dynamic Formation of Microvillus Inclusions During Enterocyte Differentiation in Munc18-2–Deficient Intestinal Organoids

2018 ◽  
Vol 6 (4) ◽  
pp. 477-493.e1 ◽  
Author(s):  
Mohammed H. Mosa ◽  
Ophélie Nicolle ◽  
Sophia Maschalidi ◽  
Fernando E. Sepulveda ◽  
Aurelien Bidaud-Meynard ◽  
...  
Keyword(s):  
Intestinal Organoids ◽  
Enterocyte Differentiation ◽  
Dynamic Formation

The use of intestinal organoids to investigate nutrient sensing

2017 ◽  
Author(s):  
Anya Ramgulam ◽  
Noemi Gonzalez-Abuin ◽  
Gary Frost ◽  
Kevin Murphy
Keyword(s):  
Nutrient Sensing ◽  
Intestinal Organoids

scholarly journals Sa1098 – Molecular Response of Canine Intestinal Organoids to Gastrointestinal Nematode Extracellular Vesicles

2019 ◽  
Vol 156 (6) ◽  
pp. S-270
Author(s):  
Yoko M. Ambrosini ◽  
Dana C. Borcherding ◽  
Todd Atherly ◽  
Wang Yuan ◽  
Michael J. Kimber ◽  
...  
Keyword(s):  
Extracellular Vesicles ◽  
Gastrointestinal Nematode ◽  
Molecular Response ◽  
Intestinal Organoids

Coating ligands mediated dynamic formation of natural organic matter (NOM) corona on engineered nanoparticles in environments

2021 ◽  
Author(s):  
Chuan-Wang Yang ◽  
Li Yuan ◽  
Hong-Zhi Zhou ◽  
Xin Zhang ◽  
Guo-Ping Sheng
Keyword(s):  
Organic Matter ◽  
Natural Organic Matter ◽  
Engineered Nanoparticles ◽  
Aquatic Systems ◽  
Solution Interface ◽  
Dynamic Formation

Natural organic matter (NOM) can adsorb onto engineered nanoparticles (ENPs) and form NOM-corona on ENPs-solution interface, thus affecting the performance and ecotoxicity of ENPs in aquatic systems. Nevertheless, the formation...

A thermo-responsive collagen-nanocellulose hydrogel for the growth of intestinal organoids

2021 ◽  
pp. 112051
Author(s):  
Rodrigo Curvello ◽  
Diana Alves ◽  
Helen E. Abud ◽  
Gil Garnier
Keyword(s):  
Intestinal Organoids

scholarly journals In vitro co-culture of human intestinal organoids and lamina propria-derived CD4+ T cells

2021 ◽  
Vol 2 (2) ◽  
pp. 100519
Author(s):  
Renée R.C.E. Schreurs ◽  
Martin E. Baumdick ◽  
Agata Drewniak ◽  
Madeleine J. Bunders
Keyword(s):  
T Cells ◽  
Lamina Propria ◽  
Cd4 T Cells ◽  
Intestinal Organoids

Hydrogen enhanced cracking via dynamic formation of grain boundary inside aluminium crystal

2021 ◽  
Vol 183 ◽  
pp. 109307
Author(s):  
De-Gang Xie ◽  
Liang Wan ◽  
Zhi-Wei Shan
Keyword(s):  
Grain Boundary ◽  
Dynamic Formation

scholarly journals Porcine small intestinal organoids as a model to explore ETEC–host interactions in the gut

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Bjarne Vermeire ◽  
Liara M. Gonzalez ◽  
Robert J. J. Jansens ◽  
Eric Cox ◽  
Bert Devriendt
Keyword(s):  
Intestinal Epithelial ◽  
Gut Health ◽  
Functional Responses ◽  
Host Pathogen Interactions ◽  
Epithelial Surface ◽  
Host Interactions ◽  
Intestinal Organoids ◽  
Host Pathogen ◽  
Small Intestinal

AbstractSmall intestinal organoids, or enteroids, represent a valuable model to study host–pathogen interactions at the intestinal epithelial surface. Much research has been done on murine and human enteroids, however only a handful studies evaluated the development of enteroids in other species. Porcine enteroid cultures have been described, but little is known about their functional responses to specific pathogens or their associated virulence factors. Here, we report that porcine enteroids respond in a similar manner as in vivo gut tissues to enterotoxins derived from enterotoxigenic Escherichia coli, an enteric pathogen causing postweaning diarrhoea in piglets. Upon enterotoxin stimulation, these enteroids not only display a dysregulated electrolyte and water balance as shown by their swelling, but also secrete inflammation markers. Porcine enteroids grown as a 2D-monolayer supported the adhesion of an F4+ ETEC strain. Hence, these enteroids closely mimic in vivo intestinal epithelial responses to gut pathogens and are a promising model to study host–pathogen interactions in the pig gut. Insights obtained with this model might accelerate the design of veterinary therapeutics aimed at improving gut health.

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