Faculty Opinions recommendation of Endocrine regulation of male fertility by the skeleton.

2011 ◽  
Author(s):  
Daniela Riccardi
Keyword(s):  
Male Fertility ◽  
Endocrine Regulation

Endocrine regulation of sperm release

2018 ◽  
Vol 30 (12) ◽  
pp. 1595 ◽  
Author(s):  
A. Kumar ◽  
S. Raut ◽  
N. H. Balasinor
Keyword(s):  
Sertoli Cell ◽  
Sertoli Cells ◽  
Male Fertility ◽  
Hormonal Control ◽  
Endocrine Regulation ◽  
Paracrine Factors ◽  
Molecular Control ◽  
Sperm Release ◽  
Multistep Process ◽  
Successful Execution

Spermiation (sperm release) is the culmination of a spermatid’s journey in the seminiferous epithelium. After a long association with the Sertoli cell, spermatids have to finally ‘let go’ of the support from Sertoli cells in order to be transported to the epididymis. Spermiation is a multistep process characterised by removal of excess spermatid cytoplasm, recycling of junctional adhesion molecules by endocytosis, extensive cytoskeletal remodelling and final spermatid disengagement. Successful execution of all these events requires coordinated regulation by endocrine and paracrine factors. This review focuses on the endocrine regulation of spermiation. With the aim of delineating how hormones control the various aspects of spermiation, this review provides an analysis of recent advances in research on the hormonal control of molecules associated with the spermiation machinery. Because spermiation is one of the most sensitive phases of spermatogenesis to variations in hormone levels, understanding their molecular control is imperative to advance our knowledge of the nuances of spermatogenesis and male fertility.

scholarly journals Endocrine Regulation of Male Fertility by the Skeleton

Cell ◽  
2011 ◽  
Vol 144 (5) ◽  
pp. 796-809 ◽  
Author(s):  
Franck Oury ◽  
Grzegorz Sumara ◽  
Olga Sumara ◽  
Mathieu Ferron ◽  
Haixin Chang ◽  
...  
Keyword(s):  
Male Fertility ◽  
Endocrine Regulation

The “soft” side of the bone: unveiling its endocrine functions

2016 ◽  
Vol 28 (1) ◽  
Author(s):  
Alfredo Cappariello ◽  
Marco Ponzetti ◽  
Nadia Rucci
Keyword(s):  
Energy Metabolism ◽  
Growth Factor ◽  
Male Fertility ◽  
Fibroblast Growth Factor 23 ◽  
Fine Tuning ◽  
Whole Body ◽  
Endocrine Regulation ◽  
Fibroblast Growth ◽  
Endocrine Organ ◽  
New Findings

AbstractBone has always been regarded as a merely structural tissue, a “hard” scaffold protecting all of its “soft” fellows, while they did the rest of the work. In the last few decades this concept has totally changed, and new findings are starting to portray bone as a very talkative tissue that is capable not only of being regulated, but also of regulating other organs. In this review we aim to discuss the endocrine regulation that bone has over whole-body homeostasis, with emphasis on energy metabolism, male fertility, cognitive functions and phosphate (Pi) metabolism. These delicate tasks are mainly carried out by two known hormones, osteocalcin (Ocn) and fibroblast growth factor 23 (FGF23) and possibly other hormones that are yet to be found. The extreme plasticity and dynamicity of bone allows a very fine tuning over the actions these hormones exert, portraying this tissue as a full-fledged endocrine organ, in addition to its classical roles. In conclusion, our findings suggest that bone also has a “soft side”, and is daily taking care of our entire organism in ways that were unknown until the last few years.

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