Faculty of 1000 evaluation for Preoperative High-resolution Magnetic Resonance Imaging Can Identify Good Prognosis Stage I, II, and III Rectal Cancer Best Managed by Surgery Alone: A Prospective, Multicenter, European Study That Recruited Consecutive Patients With Rectal Cancer.

2011 ◽  
Author(s):  
Imran Hassan ◽  
Vriti Advani
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Good Prognosis ◽  
Stage I ◽  
European Study ◽  
Resonance Imaging

Preoperative High-resolution Magnetic Resonance Imaging Can Identify Good Prognosis Stage I, II, and III Rectal Cancer Best Managed by Surgery Alone

2011 ◽  
Vol 253 (4) ◽  
pp. 711-719 ◽  
Author(s):  
Fiona G.M Taylor ◽  
Philip Quirke ◽  
Richard J Heald ◽  
Brendan Moran ◽  
Lennart Blomqvist ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Good Prognosis ◽  
Stage I ◽  
Resonance Imaging

scholarly journals Safety and Feasibility of Using Magnetic Resonance Imaging Criteria to Identify Patients With “Good Prognosis” Rectal Cancer Eligible for Primary Surgery

JAMA Oncology ◽  
2019 ◽  
Vol 5 (7) ◽  
pp. 961 ◽  
Author(s):  
Erin D. Kennedy ◽  
Marko Simunovic ◽  
Kartik Jhaveri ◽  
Richard Kirsch ◽  
Jim Brierley ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Magnetic Resonance ◽  
Good Prognosis ◽  
Resonance Imaging ◽  
Primary Surgery

scholarly journals Characteristics and Prognostic Significance of Preoperative Magnetic Resonance Imaging-Assessed Circumferential Margin in Rectal Cancer

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaoji Ma ◽  
Xinxiang Li ◽  
Linghui Xu ◽  
Debing Shi ◽  
Tong Tong ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Local Recurrence ◽  
Prognostic Significance ◽  
Preoperative Magnetic Resonance Imaging ◽  
Circumferential Margin ◽  
Resonance Imaging ◽  
Preoperative Magnetic Resonance

Purpose. To study the characteristics and prognostic significance of preoperative magnetic resonance imaging- (MRI-) assessed circumferential margin (CRM) in rectal cancer.Methods. Patients underwent preoperative high resolution pelvic MRI, followed by resection of primary tumor. The relationship between MRI-assessed CRM and pathological CRM (pCRM) was studied, and survival analysis was used to determine the prognostic significance of MRI-assessed CRM.Results. Of all the 203 patients, the total accuracy of MRI-assessed CRM for predicting involvement of pCRM was 84.2%, sensitivity was 50%, and specificity was 86.8%. Anterior tumors were more possible to assess involvement of CRM by MRI, while the false positive rate was significantly higher than lateral or posterior tumor (87.5% versus 50%,p=0.0002). The 3-year local recurrence, disease-free survival, and overall survival rates were 35.6%, 58.1%, and 85.2% in patients with involved mrCRM, compared with 8.9%, 78.9%, and 92.3% in patients with clear mrCRM. In multivariate analysis, MRI-assessed CRM found an independent risk factor for local recurrence, with a hazard ratio of 3.49 (p=0.003).Conclusions. High resolution MRI was accurate to assess CRM preoperatively, while anterior tumor should be assessed more cautiously. Involvement of mrCRM was significantly associated with local recurrence regardless of pCRM status.

scholarly journals Magnetic Resonance Imaging of Rectal Cancer

2019 ◽  
Vol 02 (01) ◽  
pp. 018-032
Author(s):  
Ekta Maheshwari ◽  
Gitanjali Bajaj ◽  
Kedar Jambhekar ◽  
Tarun Pandey ◽  
Roopa Ram
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Imaging Techniques ◽  
Postoperative Recurrence ◽  
Response To Therapy ◽  
Resonance Imaging ◽  
Primary Rectal Cancer ◽  
Magnetic Resonance Imaging Mri

AbstractHigh-resolution magnetic resonance imaging (MRI) plays a pivotal role in the pretreatment assessment of primary rectal cancer. The success of this technique depends on obtaining good-quality high-resolution T2-weighted images of the primary tumor, orthogonal to rectal lumen. The goal of magnetic resonance staging is to identify patients who will benefit from neoadjuvant therapy prior to surgery to minimize postoperative recurrence and planning of optimal surgical approach. MRI also facilitates optimal identification of important prognostic factors, which improves both treatment selection and posttreatment follow-up. The objective of this article is to review the existing literature and provide a concise update on various aspects of rectal cancer imaging, discuss the current role of advanced imaging techniques such as diffusion-weighted and perfusion imaging in the evaluation of rectal cancer, and to assess response to therapy.

Locally advanced rectal cancer: The value of magnetic resonance imaging as a predictive tool.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e14666-e14666
Author(s):  
Louise Catherine Connell ◽  
Charlotte Stuart ◽  
Norma Daly ◽  
Brian Mehigan ◽  
M. John Kennedy
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Magnetic Resonance ◽  
Locally Advanced ◽  
Stage I ◽  
Pathology Report ◽  
Resonance Imaging ◽  
Predictive Tool ◽  
Curative Intent ◽  
Mri Staging

e14666 Background: Magnetic Resonance Imaging (MRI) of pelvis stratifies patients (pts) with rectal cancer (ca) according to locally advanced disease (dx) & risk of local recurrence. By determining the extent of lymph node (LN) positivity, it enables the appropriate selection of pts for neoadjuvant therapy (NAT) prior to curative surgical resection (Sx). We assessed our institution’s experience of NAT versus upfront Sx in stage I-III rectal ca to ascertain the utility of MRI as a predictive tool in LN status evaluation. Methods: We retrospectively reviewed a prospectively maintained database for all pts with a diagnosis of stage I-III rectal ca from January 2006 to September 2012 in a specialist colorectal cancer centre. We analysed data with respect to preoperative MRI staging & definitive histopathological confirmation of LN stage. Results: A total of 210 pts were identified that had Sx for rectal ca with curative intent. Of these, 112 pts received NAT while 98 had upfront Sx. Of those who proceeded directly to Sx, there were 41 females & 57 males. Average age in this group was 73.4 years (range 33 -90). LN staging by MRI was accurate in 45.9% (n=45). LN status could not be evaluated (Nx) in 17.3% (n=17). In 19.4% (n=19) more advanced LN staging was apparent on histology while in 17.3% (n=17) LN stage was deemed more aggressive by MRI. Of those who had NAT, there were 75 males & 37 females. Average age was 62.3 years (range 26-82). In this cohort, 81.3% (n=91) had both a preoperative MRI & pathology report available for comparison. MRI in this group matched histology in 61.5% (n=56). Nx was recorded in 3.3 % (n=3). In 17.6% (n=16) more aggressive LN involvement was evident at histology while 17.6% (n= 16) had less advanced dx at tissue sampling. Overall in this study, MRI accurately predicted LN status in 53.4% (n=101). Conclusions: While MRI is a valuable tool in determining those pts with rectal ca that would benefit from NAT, its predictive value has limitations. With further analysis of the dataset at our institution, we aim to identify other factors involved & create a predictive nomogram for the rectal ca pt with locally advanced dx. We plan to validate this work by including data from other Irish cancer centres.

Preoperative assessment of prognostic factors in rectal cancer using high-resolution magnetic resonance imaging

2003 ◽  
Vol 90 (3) ◽  
pp. 355-364 ◽  
Author(s):  
G. Brown ◽  
A. G. Radcliffe ◽  
R. G. Newcombe ◽  
N. S. Dallimore ◽  
M. W. Bourne ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Prognostic Factors ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Preoperative Assessment ◽  
Resonance Imaging

scholarly journals Efficacy of High Resolution Magnetic Resonance Imaging in Preoperative Local Staging of Rectal Cancer

2013 ◽  
Vol 22 (2) ◽  
pp. 42-48 ◽  
Author(s):  
Aysun Uçar ◽  
Funda Obuz ◽  
Selman Sökmen ◽  
Cem Terzi ◽  
Özgül Sağol ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rectal Cancer ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Resonance Imaging ◽  
Local Staging

Imaging Strategies for Rectal Cancer Initial Staging: Does Pelvic Computed Tomography Provide Significantly Additional Findings when High-resolution Magnetic Resonance Imaging has Been Performed?

2020 ◽  
Vol 16 (8) ◽  
pp. 1029-1033
Author(s):  
Li-Yan Liu ◽  
Li-Heng Liu
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Rectal Cancer ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Clinical Benefit ◽  
Pelvic Bone ◽  
Resonance Imaging ◽  
New Findings ◽  
Initial Staging

Background: Initial staging of rectal cancer is done by high-resolution magnetic resonance imaging (MRI), however, pelvic computed tomography (CT) is also frequently used. The aim of this study was to evaluate the added clinical benefit of pelvic CT or whether it can alter the initial staging or not. Methods: The study was composed of 187 patients with rectal cancer. Firstly, imaging except pelvic CT was evaluated. Secondly, the pelvic CT was evaluated and the staging was adjusted according to the new findings. Subsequently, the two staging results were compared to investigate the added clinical benefit of pelvic CT. Results: Compared with the imaging data except pelvic CT, new findings revealed by the pelvic CT included metastases of the pelvic bone (n = 1) and pelvic peritoneum (n = 3). However, the new findings did not change the primary staging. Of the three patients with pelvic peritoneal metastasis, two were already determined with peritoneal involvement and ascites by abdominal CT, and the third patient was observed with liver and distant lymph node metastasis. Thus, none of their initial stagings needed to be changed. Conclusions: The addition of pelvic CT to the pre-treatment imaging strategy cannot provide added clinical benefit for the primary evaluation of rectal cancer.

Sign in / Sign up

Export Citation Format

Share Document