scholarly journals Skin diseases and coping techniques

2019 ◽  
pp. 118-125
Author(s):  
Tat'yana A. Rebeko
Keyword(s):  
Atopic Dermatitis ◽  
Skin Diseases ◽  
Control Group ◽  
Published Data ◽  
Adaptive Coping ◽  
Theoretical Hypothesis ◽  
The One ◽  
And Coping ◽  
Relationship Of ◽  
The Relationship

The study examines the relationship of non-adaptive types of coping with different forms of psychosomatic skin diseases (psoriasis and atopic dermatitis). The study involved 72 women, mean age is 37 (30 – control group (NORM), 25 – patients with atopic dermatitis (AD), 17 – patients with psoriasis (PS)). Based on published data, a theoretical hypothesis is put forward that the deformation of the early symbiotic bonds of the mother and baby (and the corresponding types of relationships with the mother) leads to the formation of a second skin and is a predictor of skin diseases. Empirical data on the similarity of the symptoms of the clinical picture of the disease and various forms of symbiosis deformity are presented. These forms are described through the metaphor of the mother's gaze – "one-sided" and "distorting". It is assumed that the "one-sided gaze" is associated with blood pressure, and the "distorting" one is associated with PS. Using nonparametric statistics methods (Kruskal-Wallis test), it is proved that non-adaptive coping in the AD and PS groups corresponds to two forms of symbiosis deformation.

scholarly journals Adipocytokines in early rheumatoid arthritis: relationship to pro- and anti-inflammatory markers

2019 ◽  
Vol 56 (6) ◽  
pp. 697-702
Author(s):  
L. V. Kondratyeva ◽  
T. V. Popkova ◽  
Yu. N. Gorbunova
Keyword(s):  
Rheumatoid Arthritis ◽  
Early Rheumatoid Arthritis ◽  
Control Group ◽  
Disease Modifying Antirheumatic Drugs ◽  
Erythrocyte Sedimentation ◽  
Anti Inflammatory ◽  
The One ◽  
Relationship Of ◽  
The Relationship ◽  
Citrullinated Peptide

Objective: to clarify the relationship of adiponectin and leptin to the signs of disease activity and the levels of pro- and anti-inflammatory cytokines in patients with early rheumatoid arthritis (RA).Subjects and methods. The investigation enrolled 27 RA patients who met the 2010 ACR/EULAR classification criteria and had never received glucocorticoids (GCs) or disease-modifying antirheumatic drugs. The median age of the patients was 56 [46; 64] years; the duration of the disease was 8 [6; 15] months. All the patients had moderate or high RA activity according to DAS28. The majority of the patients were seropositive for rheumatoid factor (88.9%) or anticyclic citrullinated peptide antibodies (96.3%). A control group included 30 gender-, age-, and body mass index (BMI)-matched people without inflammatory arthritis. Enzyme immunoassay was used to estimate the concentrations of adiponectin and leptin; XMAP multiplex assay was applied to measure the levels of interleukin-1β (IL-1β), IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-13, IL-15, IL-17 and macrophage inflammation proteins (MIP), such as MIP-1α and MIP-1β.Results and discussion. In RA patients, adiponectin concentrations were higher (p<0.001) and leptin levels and leptin/adiponectin (L/A) ratios were lower than those in the controls (p=0.04 and p<0.001, respectively). In RA, there were direct correlations of leptin levels with concentration of IL-17 (r=0.4; p=0.03), IL-4 (r=0.39; p=0.04) and erythrocyte sedimentation rate (ESR) (r=0.3; p=0.05), as well as relationships of L/A ratios to ESR (r=0.38; p=0.05) and the levels of CRP (r=0.4; p=0.04) and MIP-1β (r=0.55; p=0.03). An increase in adiponectin concentrations was associated with a decrease in MIP-1β levels (r=-0.63; p<0.01). In patients with BMI ≥25 kg/m2, leptin concentrations were comparable in RA patients and controls (p=0.1); the differences in adiponectin levels and L/A ratios remained in both cases (p<0.001). This subgroup of patients with RA showed significant correlations between leptin and IL-17 levels (r=0.52; p=0.03), adiponectin and MIP-1β concentrations (r=-0.59; p=0.01), L/A ratios and MIP-1β levels (r=0.55; p=0.02).Conclusion. In early RA, there was a lower leptin synthesis and a higher adiponectin production. The correlations between the levels of adipocytokines, IL-17, and MIP1β, on the one hand, suggest that adipose tissue has an impact on systemic inflammation and, on the other, confirm that proinflammatory cytokines are involved in the development of insulin resistance and obesity.

Antipruritic therapy issues on background of skin xerosis

2021 ◽  
pp. 37-41
Author(s):  
L. S. Kruglova ◽  
E. V. Tipaeva
Keyword(s):  
Atopic Dermatitis ◽  
Clinical Practice ◽  
Drug Therapy ◽  
Skin Diseases ◽  
Transepidermal Water Loss ◽  
Topical Drugs ◽  
Antipruritic Therapy ◽  
Therapeutic Measures ◽  
Relationship Of ◽  
The Relationship

The relationship of xerosis with various skin diseases is very multifaceted, at the same time, xerosis can be the cause of the onset or aggravation of itching. Modern recommendations for the external treatment of chronic dermatoses, accompanied by xerosis and itching, imply two directions: direct therapeutic measures during an exacerbation and the use of dermatocosmetics adapted to certain symptoms.Material and methods. We observed 26 patients (mean age 38.7 ± 1.9 years with atopic dermatitis, eczema, psoriasis or pruritus, where xerosis was present in the clinical picture and pruritus was noted. All patients used topical drugs in accordance with the nosology, in as an adjuvant therapy – Neotanin Comfort Plus cream.Research results. In atopic dermatitis, the corneometry index increased by an average of 21%, with eczema – by 20%, with psoriasis – by 22%, with skin itching – by 12%. Transepidermal water loss decreased in atopic dermatitis by 19.8%, with eczema – by 22.8%, with psoriasis – by 21.8%, with pruritus – by 18.4% The value of the total BRS index decreased by more than two times.Conclusion. The use of Neotanin Comfort Plus cream in combination with topical drug therapy (GCS, multicomponent drugs) is highly effective and safe in patients with atopic dermatitis, eczema, psoriasis or pruritus, which makes it possible to recommend it for use in wide clinical practice.

scholarly journals SELF-EFFICACY AND COPING BEHAVIOUR OF STUDENTS DURING THEIR STUDIES AT A UNIVERSITY

2020 ◽  
pp. 118-123 ◽  
Author(s):  
Irina A. Umanskaya ◽  
Valeriy V. Golubev
Keyword(s):  
Coping Strategies ◽  
Personality Characteristic ◽  
Coping With Stress ◽  
Main Hypothesis ◽  
Self Monitoring ◽  
Coping Behaviour ◽  
The One ◽  
And Coping ◽  
Relationship Of ◽  
The Relationship

The article is devoted to the problem of the relationship of personality self-effi cacy and coping behaviour among university students. The authors demonstrate topicality of considering the aspect of coping with life diffi culties among students in connection with the high requirements of society for future professionals, on the one hand, and the high psychological load in the learning process, which leads to stress, on the other hand. Researchers consider self-effi cacy as a resource for coping with stress, and as a personality characteristic that depends on the success of solving diffi cult problems. The study was aimed at solving several problems: comparing the level of general self-effi cacy, self-effi cacy in activities and in the fi eld of communication among students of different courses; identifi cation of the relationship between the level of self-effi cacy and coping strategies in stressful situations for students of different courses (this is the main hypothesis of the study). As a result, the relationship between self-effi cacy and such coping strategies as self-monitoring and activity planning, as well as a strategy for avoiding diffi culties, is shown. However, the assumption that the level of self-effi cacy increases and the choice of coping strategies varies signifi cantly from course to course has not been confi rmed. There is also no connection with sociopsychological adaptation.

STRATEGI KOPING ORANG TUA TERHADAP ANAK AUTIS DAN POLA ASUH ORANG TUA

2018 ◽  
Vol 11 (2) ◽  
pp. 196-204
Author(s):  
Asirotul Ma’rifah ◽  
Naning Puji Suryantini Suryantini ◽  
Rina Mardiyana
Keyword(s):  
Coping Strategies ◽  
Sampling Technique ◽  
Children With Autism ◽  
Adaptive Coping ◽  
Autistic Children ◽  
Cross Sectional ◽  
Authoritarian Parenting ◽  
Cross Tabulation ◽  
Relationship Of ◽  
The Relationship

Autism is still a nightmare for most parents. Parents with autism can be very stressful when dealing with a hyperactive child's behavior, aggressive and passive. Stress experienced by parents of children with autism will affect the ability of parents in the parenting role, especially in relation to coping strategies have in dealing with problems of children. The participation of parents is crucial the success of socializing with children with autism in the general population. This study aims to determine the relationship of coping strategies parents of autistic children and parenting parents. This type of research is an analytic correlation with cross sectional approach. The population in this study were all parents of autistic children in SLB Muhammadiyah Mojokerto numbering 15 people. Samples in this study were all parents of autistic children in SLB Muhammadiyah Mojokerto which totaled 15 people by using total sampling technique. Collecting data using questionnaires. Data analized use cross tabulation, presented in a frequency distribution. On cross-tabulation obtained results tend to use maladaptive coping strategies permissive parenting that is 8 (53.3%), there are also respondents who use adaptive coping strategies using authoritarian parenting as much as one person (16.7%), and adaptive coping strategies tend using democratic parenting style as much as 5 people (33.3%). Expected parents still seeking information to broaden their parents on coping strategies of parents of autistic children and parenting parents as well as parents to give special attention for children with autism to the development and advancement of their lives because they have the same rights as any other normal child.

Pensare Dio. Spunti di riflessione in dialogo con Anca Vasiliu

Elenchos ◽  
2020 ◽  
Vol 41 (1) ◽  
pp. 181-194
Author(s):  
Angela Longo
Keyword(s):  
Late Antiquity ◽  
Human Being ◽  
Common Thread ◽  
Critical Issues ◽  
Relevant Topic ◽  
The Common ◽  
The One ◽  
Relationship Of ◽  
The Relationship ◽  
The Trinity

AbstractThe following work features elements to ponder and an in-depth explanation taken on the Anca Vasiliu’s study about the possibilities and ways of thinking of God by a rational entity, such as the human being. This is an ever relevant topic that, however, takes place in relation to Platonic authors and texts, especially in Late Antiquity. The common thread is that the human being is a God’s creature who resembles him and who is image of. Nevertheless, this also applies within the Christian Trinity according to which, not without problems, the Son is the image of the Father. Lastly, also the relationship of the Spirit with the Father and the Son, always within the Trinity, can be considered as a relationship of similarity, but again not without critical issues between the similarity of attributes, on the one hand, and the identity of nature, on the other.

scholarly journals Evaluation of the relationship between perceived social support, coping strategies, anxiety, and depression symptoms among hospitalized COVID-19 patients

2020 ◽  
pp. 009121742098208
Author(s):  
Ali Kandeğer ◽  
Memduha Aydın ◽  
Kürşat Altınbaş ◽  
Alparslan Cansız ◽  
Özge Tan ◽  
...  
Keyword(s):  
Social Support ◽  
Coping Strategies ◽  
Perceived Social Support ◽  
Depression Scale ◽  
Negative Association ◽  
Anxiety And Depression ◽  
Control Group ◽  
Depression Symptoms ◽  
Adaptive Coping ◽  
The Relationship

Objective We aimed to evaluate the relationship between perceived social support, coping strategies, anxiety, and depression symptoms among hospitalized COVID-19 patients by comparing them with a matched control group in terms of age, gender, and education level. Method The patient group (n = 84) and the healthy controls (HCs, n = 92) filled in the questionnaire including the socio-demographic form, Hospital Anxiety Depression Scale, Multidimensional Perceived Social Support Scale, and Brief Coping Orientation to Problems Experienced through the online survey link. Results The COVID-19 patients had higher perceived social support and coping strategies scores than the HCs. However, anxiety and depression scores did not differ significantly between the two groups. In logistic regression analysis performed in COVID-19 patients, the presence of chest CT finding (OR = 4.31; 95% CI = 1.04–17.95) was a risk factor for anxiety and the use of adaptive coping strategies (OR = 0.86; 95% CI = 0.73–0.99) had a negative association with anxiety. In addition, the use of adaptive coping strategies (OR = 0.89; 95% CI = 0.79–0.98) and high perceived social support (OR = 0.97; 95% CI = 0.93– 0,99) had a negative association with depression symptoms. Conclusions Longitudinal studies involving the return to normality phase of the COVID-19 pandemic are needed to investigate the effects of factors such as coping strategies and perceived social support that could increase the psychological adjustment and resilience of individuals on anxiety and depression.

scholarly journals Socio-legal studies and the humanities – law, interdisciplinarity and integrity

2009 ◽  
Vol 5 (3) ◽  
pp. 243-261 ◽  
Author(s):  
Melanie L. Williams
Keyword(s):  
Human Experience ◽  
Normative Values ◽  
Moral Sensibility ◽  
Hard Data ◽  
Legal Studies ◽  
Psychological Significance ◽  
The One ◽  
Relationship Of ◽  
The Relationship

This paper was delivered as a plenary lecture, designed to respond to the one-day special conference focus upon links between socio-legal studies and the humanities.1 The paper focuses in particular upon the relationship between law and the humanities. It may be argued that the role of empirically sourced socio-legal research is well accepted, given its tangible utility in terms of producing hard data which can inform and transform policy perspectives. However, scholarly speculation about the relationship between law and the humanities ranges from the indulgent to the hostile. In particular, legal scholars aligning themselves as ‘black letter’ commentators express strong opinions about such links, suggesting that scholarship purporting to establish links between the two fields is essentially spurious, bearing in mind the purposive role of law as a problem-solving mechanism. The paper sets out to challenge such assertions, indicating the natural connections between the two fields and the philosophical necessity of continued interaction, given the fact that certain aspects of human experience and nature cannot be plumbed by doctrine or empiricism or even by combinations of the two. Law must be understood to stand at the nexus of human experience, in a relationship of integrity, where the word is understood to mean both morally principled and culturally integrated. In particular, the development of human qualities, of character and moral sensibility informing normative values – and, ultimately, engagement with the world of law – is a process of subtle cultural as well as psychological significance, and may benefit from interrogation deriving from the wider fields of human discourse.

Experimental study of the inhibition effect of CXCL12/CXCR4 in malignant pleural mesothelioma

2018 ◽  
Vol 67 (2) ◽  
pp. 338-345 ◽  
Author(s):  
Jianshuang Li ◽  
Tong Li ◽  
Shuo Li ◽  
Lipeng Xie ◽  
Yi-Lin Yang ◽  
...  
Keyword(s):  
Treatment Group ◽  
Malignant Pleural Mesothelioma ◽  
Synergistic Effects ◽  
Control Group ◽  
Pleural Mesothelioma ◽  
Gene Expressions ◽  
Relationship Of ◽  
The Relationship ◽  
Cxcr4 Axis

Previous studies have demonstrated that CXCL12/CXCR4 axis is closely related to tumors such as malignant pleural mesothelioma (MPM). This research was conducted in order to detect whether CXCL12/CXCR4 inhibitors could restrain MPM and have a synergistic effect with chemotherapy, also to investigate the relationship of CXCL12/CXCR4 with other gene expressions in MPM. Forty mice were injected MPM cells and randomly divided into four groups: the PBS (control group), AMD3100 (CXCR4-CXCL12 antagonist), pemetrexed and AMD3100 plus pemetrexed. The mice were treated respectively for duration of 3 weeks. The size, bioluminescence and weight of tumors were measured. The differences between gene expressions in each group were analyzed. The tumor weights of each treatment group were lower than that of the control group (p<0.05). The bioluminescence of the tumor of the AMD3100 treatment group and the AMD3100 plus pemetrexed treatment group were lower than that of the control group (p<0.05), and AMD3100 was shown to have synergistic effects with pemetrexed (p<0.05). Among the 2.5 billion genes, several hundreds of genes expressed differently between groups. Results show that AMD3100 and pemetrexed can inhibit the growth of MPM in vivo, also that there is a better result if both are used together. Our findings suggest that CXCL12/CXCR4 axis affects a certain amount of gene expression in MPM.

Racial Differences In The Relationship Of Total and Food-Specific IgE To Atopic Dermatitis In Childhood

2014 ◽  
Vol 133 (2) ◽  
pp. AB196
Author(s):  
Gillian Bassirpour ◽  
Edward M. Zoratti ◽  
Ganesa Wegienka ◽  
Suzanne Havstad ◽  
Alexandra Sitarik ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Racial Differences ◽  
Specific Ige ◽  
Food Specific Ige ◽  
Relationship Of ◽  
The Relationship

scholarly journals Reduced loss aversion in subclinical negative symptoms and hypomania

2020 ◽  
Author(s):  
Federica Klaus ◽  
Justin Chumbley ◽  
Erich Seifritz ◽  
Stefan Kaiser ◽  
Matthias Hartmann-Riemer
Keyword(s):  
Loss Aversion ◽  
Negative Symptoms ◽  
Control Group ◽  
Inverse Relation ◽  
Symptom Dimensions ◽  
Binary Choices ◽  
Relationship Of ◽  
The Relationship ◽  
Behavioral Phenomenon ◽  
Higher Sensitivity

AbstractLoss aversion is a behavioral phenomenon that describes a higher sensitivity to losses than to gains and influences decisions. Decision-making is altered in several psychopathologic states, such as in the two symptom dimensions of hypomania and negative symptoms. It has been argued that progress in our understanding of psychopathology requires a reorientation from the traditional, syndrome-based perspective to a more detailed study of individual constituent symptoms. In the present study, we made careful efforts to dissociate the relationship of loss aversion to negative symptoms, from its relationship with hypomanic symptoms. We selected a sample of 45 subjects from a healthy student population (n = 835) according to psychopathologic scales for hypomania and negative symptoms and stratified them into a control group (n = 15), a subclinical hypomania group (n = 15) and a negative symptoms group (n = 15). Participants completed a loss aversion task consisting of forced binary choices between a monetary gamble and a riskless choice with no gain or loss. We found, that these two symptom dimensions of hypomania and negative symptoms have a similar inverse relation to loss aversion as demonstrated by analysis of variance. Further research is warranted to describe the underlying psychological and neurobiological mechanisms at play. Given the partially opposing nature of hypomania and negative symptoms it further needs to be elucidated whether they are linked to loss aversion via dissociable mechanisms.

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