scholarly journals Comparison of dexmedetomidine and fentanyl as adjuvant to intrathecal levobupivacaine in lower segment cesarean section: A prospective, randomized double blind study

2020 ◽  
Vol 24 (4) ◽  
Author(s):  
Kapil Rastogi ◽  
Alok Kumar Bharti ◽  
Yashpal Singh ◽  
Pushkar Ranjan

Intrathecal Bupivacaine is most commonly used local anesthetic for lower segment cesarean section (LSCS) but there is constant endeavour for search of a local anesthetic (LA) which has improved safety profile for mother as well as foetus. So far many adjuvants like fentanyl, morphine or tramadol etc. has been used with intrathecal LA to prolong intraoperative anesthesia and postoperative analgesia.

2013 ◽  
Vol 20 (03) ◽  
pp. 409-415
Author(s):  
ASHFAQ AHMED ◽  
MOHAMMAD ASLAM

Objectives: To compare the efficacy of low-dose prophylactic use of ketamine with ketamine plus midazolam for theprevention of shivering caused by spinal anesthesia, during lower segment cesarean section. Main Outcome Measures: Heamodynamicmonitoring, avoidance of lactic acidosis/ increased carbon dioxide production and patient satisfaction. Design: Prospective RandomizedControlled trial. Place: Department of Anesthesia and ICU PNS Shifa Karachi. Duration of study: March 2010 to June 2010. Patients andMethods: 100 ASA-I & II consecutive patients who reported for LSCS in PNS Shifa Hospital were studied. In this double-blind study,patients were randomly allocated to receive ketamine alone (Group I, n= 50), and ketamine plus midazolam (Group II, n = 50). Afterstandardized Spinal anesthesia, a shivering was recorded at 5 min intervals for 15 minutes. Results: Shivering was observed in 9/50(18%) patients of group I (Ketamine only) as compared to only 2/50 (4%) patients in Group II (ketamine + midazolam) (p=0.025) whichis statically significant. The two groups were comparable regarding distribution of age (p=0.37), BMI (p=0.27) and duration of surgery.Results were analyzed by using chi square test. Conclusions: The efficacy of i.v. ketamine plus midazolam is better as compared to lowdosei.v. ketamine alone in preventing shivering in lower segment Cesarean Section patients, during spinal anesthesia.


Pain ◽  
1982 ◽  
Vol 14 (2) ◽  
pp. 202
Author(s):  
E. Lanz ◽  
D. Theiss ◽  
W. Reiss ◽  
U. Sommer

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