A review of experimental designs of compound compatibility law of traditional Chinese medicine

2003 ◽  
Vol 1 (3) ◽  
pp. 177-179
Author(s):  
Xiao-Li Song
2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Haiyin Huang ◽  
Jiaqi An ◽  
Lizhi Lu ◽  
Mingli Wang ◽  
Huijia Chen ◽  
...  

More and more scholars choose N-of-1 trials for TCM clinical research. However, the quality of the experimental designs was uneven. Accumulating more than eight years of experience in exploring the N-of-1 trials of TCM, the authors and their team searched the related literature in main Chinese and English databases, referenced to relevant Chinese and international guidelines. The design, implementation, and data analysis of N-of-1 trials of TCM are still in in-depth exploration and practice. “Carryover effect” may affect the design and quality of the trials. Individualized treatment should be guided by the classic theories of TCM. It is expected to formulate reasonable observation periods and pairs and closely integrate individual and group statistical analysis.


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