scholarly journals Dysphagia, reflux and related sequelae due to altered physiology in scleroderma

2021 ◽  
Vol 27 (31) ◽  
pp. 5201-5218
Author(s):  
Anusri Kadakuntla ◽  
Ankit Juneja ◽  
Samantha Sattler ◽  
Anusha Agarwal ◽  
Drishti Panse ◽  
...  
Keyword(s):  
Altered Physiology

NEWER CONCEPTS IN EMERGENCY CARE OF CHILDREN WITH MAJOR INJURIES

PEDIATRICS ◽  
1973 ◽  
Vol 52 (4) ◽  
pp. 485-487
Author(s):  
J. Alex Haller
Keyword(s):  
Multiple Injuries ◽  
Treatment Center ◽  
Injured Child ◽  
Small Children ◽  
Trauma Unit ◽  
Efficient Management ◽  
Life Threatening ◽  
Total Investment ◽  
Special Challenge ◽  
Altered Physiology

Childhood trauma and other life-threatening emergencies require facilities operational on a 24-hour basis, with surgical and medical components, x-ray facilities, and blood and chemistry laboratories organized to provide primary resuscitation and initial management for extensive and multiple injuries in children. Staffed to provide high quality treatment for simpler injuries and emergency illnesses in children, a trauma unit should represent a complete emergency treatment center for children; it should be tied administratively and professionally to the intensive care units within the larger medical complex. From this type of organizational framework and a physically separate trauma unit for children, improved teamwork and more efficient management of multiple injuries should result. The basic principles of rapid, careful evaluation and sequential correction of altered physiology remain the back-bone of successful therapy in children. The unique metabolic demands and miniature anatomic relationships, especially of small children, present the physician with a special challenge and a tremendous responsibility. Rewards for the successful management of multiple trauma are high–the younger the injured child, the greater is our total investment in his welfare and in his future.

Severe Salmonella Gastroenteritis Associated with Hypochlorhydria

1971 ◽  
Vol 16 (5) ◽  
pp. 255-258 ◽  
Author(s):  
J. A. Gray ◽  
Angela M. Trueman
Keyword(s):  
Gastric Juice ◽  
Pernicious Anaemia ◽  
Gastric Surgery ◽  
Aetiological Factor ◽  
Diarrheal Illness ◽  
Altered Physiology ◽  
Salmonella Enteritis ◽  
Seriously Ill

An unusually severe and prolonged salmonella enteritis is described in 6 adults; 5 had previously undergone gastric surgery and one had pernicious anaemia. Possible causes are discussed but the probable common aetiological factor was deficient gastric juice. Hypo- or achlorhydric subjects appear more prone to salmonellosis and may become seriously ill as a result. Any diarrheal illness in them should be investigated by the bacteriologist before being attributed to altered physiology alone.

scholarly journals An I for an A: Dynamic Regulation of Adenosine Deamination-Mediated RNA Editing

Genes ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 1026
Author(s):  
Cornelia Vesely ◽  
Michael F. Jantsch
Keyword(s):  
Rna Editing ◽  
Endogenous Retrovirus ◽  
Dynamic Regulation ◽  
Adenosine Deaminases ◽  
Specific Regulation ◽  
Altered Physiology ◽  
Adenosine Deamination ◽  
Different Levels ◽  
Pathogen Exposure ◽  
Different Tissues

RNA-editing by adenosine deaminases acting on RNA (ADARs) converts adenosines to inosines in structured RNAs. Inosines are read as guanosines by most cellular machineries. A to I editing has two major functions: first, marking endogenous RNAs as “self”, therefore helping the innate immune system to distinguish repeat- and endogenous retrovirus-derived RNAs from invading pathogenic RNAs; and second, recoding the information of the coding RNAs, leading to the translation of proteins that differ from their genomically encoded versions. It is obvious that these two important biological functions of ADARs will differ during development, in different tissues, upon altered physiological conditions or after exposure to pathogens. Indeed, different levels of ADAR-mediated editing have been observed in different tissues, as a response to altered physiology or upon pathogen exposure. In this review, we describe the dynamics of A to I editing and summarize the known and likely mechanisms that will lead to global but also substrate-specific regulation of A to I editing.

Altered physiology in trehalose-producing transgenic tobacco plants: Enhanced tolerance to drought and salinity stresses

2005 ◽  
Vol 48 (4) ◽  
pp. 456-466 ◽  
Author(s):  
Sung-Soo Jun ◽  
Jin Young Yang ◽  
Hye Jin Choi ◽  
Na-Ryung Kim ◽  
Min Chul Park ◽  
...  
Keyword(s):  
Transgenic Tobacco ◽  
Transgenic Tobacco Plants ◽  
Tobacco Plants ◽  
Altered Physiology

scholarly journals Perioperative analgesia in obese patients

2021 ◽  
Vol 17 (5) ◽  
pp. 18-26
Author(s):  
S.I. Vorotyntsev
Keyword(s):  
Pain Management ◽  
Improve Patient Safety ◽  
Multimodal Analgesia ◽  
The Body ◽  
Obese Patients ◽  
Perioperative Analgesia ◽  
Perioperative Pain ◽  
Opioid Sparing ◽  
Perioperative Pain Management ◽  
Altered Physiology

Obesity in general and morbid obesity (MO) in particular are becoming more common around the world. MO is associated with altered physiology of the body and increased number of comorbidities, which can make perioperative pain control particularly difficult in such patients. Given the higher incidence of respiratory disorders, traditional opioid-oriented treatment of pain in patients with MO can often lead to ventilation disorders and increased morbidity and/or mortality. Multimodal analgesia strategies based on a step-by-step, according to the pain severity, opioid-sparing approach can improve patient safety and treatment outcomes. Further progress in understanding the mechanisms of acute pain forces doctors to actively detect and treat both its nociceptive and pro-nociceptive components (hyperalgesia, etc.). Such multimodal analgesia protocols should be standardized and implemented in perioperative care of patients with MO. In addition to standardizing the treatment of postoperative pain, regardless of used regimen of anesthesia and analgesia, some patients with MO require enhanced respiratory monitoring to prevent possible airway side effects. This review briefly describes the physiological changes in obese patients, the pathophysiology of pain, and the evidence-based clinical updates for pain management in MO. Also, the role of opioid-sparing pharmacological adjuvants is discussed and future directions of research in the field of perioperative pain management in patients with MO are highlighted.

scholarly journals Cardiovascular Changes in Smoker and Nonsmoker Male Stroke Patients

2010 ◽  
Vol 14 (Number 1) ◽  
pp. 32-35
Author(s):  
N Habib ◽  
Md. R Amin ◽  
US N Begum ◽  
N Akhter ◽  
D Akther ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Descriptive Study ◽  
Stroke Patients ◽  
Medical College ◽  
Significant Difference ◽  
Group A ◽  
Altered Physiology ◽  
Group B

This descriptive study was done in the Deponment of Physiology. Dhaka Medical College, Dhaka. during the period of January 2008 to December 2008. The objective of the study was to measure pulse and blood pressure in smokers and nonsmoker adult male stroke patients and to find out changes in pulse and blood pressure among the smoker and non-smoker stroke patients. To accomplish this purpose 105 patient of over 20 years of age were selected. They were divided into two groups: Group A consisting of thirty n on-smoker and group B consisting of seven,' five smoker stroke patients. The finding showed that smoking caused no statistical significant difference 1p>0.05) in pulse and systolic blood pressure among she groups. Diastolic blood pressure was significantly higher (p<0.05) fill smokers than non-smokers. The study therefore provides the scope to understand the altered physiology of smoker stroke pollen's.

Medical conditions during pregnancy

2017 ◽  
Author(s):  
Janet Medforth ◽  
Linda Ball ◽  
Angela Walker ◽  
Sue Battersby ◽  
Sarah Stables
Keyword(s):  
Renal Transplant ◽  
Insulin Dependent Diabetes ◽  
Renal Diseases ◽  
Medical Conditions ◽  
Management Options ◽  
Clinical Observations ◽  
Insulin Dependent ◽  
Laboratory Investigations ◽  
Altered Physiology ◽  
Diabetes Gestational

This chapter comprises a review of common medical conditions, including asthma, thyroid conditions, cardiac conditions, and renal diseases. There is a small section on renal transplant and care of the woman during pregnancy. Insulin-dependent diabetes, non-insulin-dependent diabetes, gestational diabetes, and their impact on pregnancy are discussed. The effect of pregnancy on the conditions themselves is reviewed, along with recognition and management of pregnancy changes due to the condition. Pregnancy management options, including altered physiology and pharmacological treatment, are discussed. Clinical and laboratory investigations are also listed. The section on cardiac conditions refers to circulatory changes during pregnancy and how these may be affected by a range of different cardiac conditions, both those that are congenital and those acquired. Pregnancy management, investigations, and clinical observations used to detect deterioration are included.

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