scholarly journals Pulmonary Artery Hypertension in Acyanotic Congenital Heart Disease Underwent Transcatheter Closure at Dr. Soetomo Hospital

2021 ◽  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Pulmonary Artery ◽  
Congenital Heart ◽  
Transcatheter Closure ◽  
Pulmonary Artery Hypertension ◽  
Acyanotic Congenital Heart Disease

Transcatheter Treatment of Aortopulmonary Window with a Symmetrical Membranous Ventricular Septal Occluder

Cardiology ◽  
2017 ◽  
Vol 138 (2) ◽  
pp. 76-79 ◽  
Author(s):  
Hai-Xia Xu ◽  
Dong-Dong Zheng ◽  
Min Pan ◽  
Xiao-Fei Li
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Pulmonary Artery ◽  
Congenital Heart ◽  
Surgical Intervention ◽  
Transcatheter Closure ◽  
Aortopulmonary Window ◽  
Transcatheter Device

Aortopulmonary window (APW), the presence of a communication between aorta and pulmonary artery, is a rare congenital heart disease, and surgical intervention is the standard for closure. Recently, several cases have been treated with transcatheter device occluders. Here, we report an APW patient treated successfully using a transcatheter closure with a symmetrical membranous ventricular septal occluder. We are the first to report on a case treated with this type of occluder for APW.

scholarly journals Serum Levels of Soluble ICAM-1 in Children with Pulmonary Artery Hypertension

2014 ◽  
Vol 41 (2) ◽  
pp. 159-164 ◽  
Author(s):  
Melahat Melek Oguz ◽  
Ayse Deniz Oguz ◽  
Cihat Sanli ◽  
Ayhan Cevik
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Pulmonary Artery ◽  
Congenital Heart ◽  
Pulmonary Artery Hypertension ◽  
Assay Method ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Subjects ◽  
Healthy Control ◽  
The Mean

This prospective cross-sectional study attempted to determine both the usefulness of the serum intercellular adhesion molecule-1 (ICAM-1) as a biomarker for pulmonary artery hypertension secondary to congenital heart disease and the nature of this marker's association with catheter angiographic findings. Our study included a total of 70 male and female children, comprising 30 patients with both pulmonary artery hypertension and congenital heart disease, 20 patients with congenital heart disease alone, and 20 healthy control subjects. Levels of ICAM-1 in plasma samples from all groups were measured by the enzyme-linked immunosorbent assay method. Cardiac catheterization was also performed in all patients. The mean serum ICAM-1 levels in pediatric patients who had congenital heart disease with and without pulmonary artery hypertension were 349.6 ± 72.9 ng/mL and 312.3 ± 69.5 ng/mL, respectively (P=0.002). In healthy control subjects, the mean serum ICAM-1 level was 231.4 ± 60.4 ng/mL. According to the results of this study, the ICAM-1 level of the pulmonary artery hypertension group was significantly higher than those of the congenital heart disease group and the healthy control group. Correlation analysis showed that ICAM-1 level was correlated with systolic and mean pulmonary artery pressures (r=0.62, P=0.001; r=0.57, P=0.001)—which are 2 important values used in diagnosis of pulmonary artery hypertension. Moreover, receiver operating characteristic analysis yielded consistent results for the prediction of pulmonary artery hypertension. Therefore, we conclude that ICAM-1 has potential use as a biomarker for the diagnosis and follow-up of pulmonary artery hypertension.

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