scholarly journals Evaluation of Scanning Condition and Early Organ Accumulation with Large Field of View Gamma Camera in 201Tl Myocardial Scan

RADIOISOTOPES ◽  
1976 ◽  
Vol 25 (12) ◽  
pp. 794-799 ◽  
Author(s):  
Hisashi BUNKO ◽  
Norihisa TONAMI ◽  
Kinichi HISADA
Keyword(s):  
Gamma Camera ◽  
Field Of View ◽  
Large Field

Sentinel Node Detection with Imaging Probe

2002 ◽  
Vol 88 (3) ◽  
pp. S32-S35 ◽  
Author(s):  
O Schillaci ◽  
G D'Errico ◽  
R Scafè ◽  
A Soluri ◽  
N Burgio ◽  
...  
Keyword(s):  
Orthopedic Surgery ◽  
Gamma Camera ◽  
Field Of View ◽  
Large Field ◽  
Sentinel Node Detection ◽  
Subjective Impression ◽  
Imaging Probe ◽  
Multicenter Trials ◽  
The Mean ◽  
Cooperative Project

A one-square-inch-field-of-view mini gamma camera, whose first prototype was built by us in 1998 and given the name imaging probe (IP), was initially employed in sentinel lymph node (SLN) detection. This is probably the best way of learning how to use it. In the present work IP was used for SLN localization by a medical team that, after having been trained by the group of nuclear physicians of “La Sapienza” University who designed and first used the detector, used IP at their own hospital to 1) acquire experience for future use during surgery (a cooperative project on IP-radioguided orthopedic surgery is ongoing) and 2) start multicenter trials with IP. The SLN was identified and localized with IP and a non-imaging probe, Neoprobe 2000, in six patients with breast cancer who underwent lymphoscintigraphy for SLN biopsy. The operators who used Neoprobe and IP were blinded to each other's findings and to the results obtained with the large-field-of-view Anger camera that was used for lymphoscintigraphy. The Anger camera, IP and Neoprobe detected seven SLNs in six patients. The mean detection time was 2 mins 6 s (standard deviation (SD) 26 s) with IP, and 2 mins 18 s (SD 47 s) with Neoprobe 2000. The SLN that was most difficult to find was detected in 2 mins 56 s with IP and 3 mins 45 s with Neoprobe. The operators' subjective impression of having detected the SLN was “absolutely sure” for 7/7 nodes with IP and “absolutely sure” for 5/7 nodes with Neoprobe.

Thrombus Imaging with 99mTc-Hmpao-Labeled Platelets and 111In-Labeled Monoclonal Antifibrin Antibodies

1993 ◽  
Vol 34 (1) ◽  
pp. 59-63 ◽  
Author(s):  
M. S. Vorne ◽  
T. T. Honkanen ◽  
T. J. Lantto ◽  
R. O. Laitinen ◽  
K. J. Karppinen ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Gamma Camera ◽  
Lower Extremities ◽  
Field Of View ◽  
Large Field ◽  
Thrombus Imaging ◽  
99Mtc Hmpao

Eighteen patients with suspicion of deep venous thrombosis (DVT) in the lower extremities were imaged both with autologous 99mTc-HMPAO-labeled platelets (Tc-PLT) and 111In-labeled monoclonal antifibrin antibodies (In-MoAbs) on the same day. Presence or absence of thrombosis was verified by venography. Tc-PLT was given i.v. followed after 30 min by In-MoAbs. Anterior and posterior projections of the lower extremities were obtained with a large field-of-view gamma camera at 5 to 25 min, 2 h, 4 to 6 h, and 20 h after administration of the marker. Both Tc-PLT and In-MoAbs detected DVT well but less frequently than venography. Thrombi were visualized at 2 to 4 h after injection. The quality of images was better with Tc-PLT than with In-MoAbs. In the patients treated during the study, heparin significantly (p < 0.01) inhibited the uptake of Tc-PLT but not of In-MoAbs. We conclude that both Tc-PLT and In-MoAbs are suitable agents for the detection of DVT especially in patients without anticoagulation.

Routine 18F-2-Deoxy-2-Fluoro-D-Glucose (18F-FDG) Myocardial Tomography Using a Normal Large Field of View Gamma-Camera

Angiology ◽  
1989 ◽  
Vol 40 (12) ◽  
pp. 1058-1064 ◽  
Author(s):  
F. Höflin ◽  
H. Ledermann ◽  
U. Noelpp ◽  
R. Weinreich ◽  
H. Rösler
Keyword(s):  
Gamma Camera ◽  
Field Of View ◽  
Large Field ◽  
18F Fdg

scholarly journals Technetium-99m scintimammography in the diagnosis of malignant breast tumors

2004 ◽  
Vol 61 (1) ◽  
pp. 35-40
Author(s):  
Ljiljana Jaukovic
Keyword(s):  
Gamma Camera ◽  
Breast Disease ◽  
Field Of View ◽  
Large Field ◽  
Imaging Method ◽  
Diagnostic Reliability ◽  
Technetium 99M ◽  
99Mtc Tetrofosmin ◽  
Malignant Breast ◽  
Sensitivity Specificity

Background. Technetium-99m (99mTc) tetrofosmin scintigraphy is a new imaging method for the diagnosis of various malignancies, such as lung, thyroid, and most frequently breast neoplasms. The aim of this study was to evaluate the diagnostic reliability of 99mTc-Tetrofosmin breast scintigraphy in the detection of malignant breast disease. Methods. 99mTc -Tetrofosmin scintimammography (SMM) was performed in 28 patients with 30 breast lesions suspicious for malignancy. Standard mammography (MM) was also done. After surgery, the results of SMM and MM were compared to definitive histopathological findings as the "gold standard". After intravenous injection of radiotracer, SMM was performed in prone and supine views of the thorax, using large field-of-view Gamma camera. Results. The results of SMM were interpreted visually and semiquantitatively, and evaluated as positive or negative. Sensitivity, specificity and accuracy, positive (PPV) and negative predictive value (NPV) were obtained in relation to histopathology. After comparing the results of SMM and MM, SMM was proved more sensitive (95% for SMM vs. 80% for MM), while the specificity of both methods was similar. Conclusion. The results of this study indicate that the contribution of SMM as a nuclear medicine procedure has its place in the diagnostic protocol for patients suspected of malignant breast cancer.

scholarly journals Intraoperative Scintigraphy Using a Large Field-of-View Portable Gamma Camera for Primary Hyperparathyroidism: Initial Experience

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Nathan C. Hall ◽  
Robert L. Plews ◽  
Amit Agrawal ◽  
Stephen P. Povoski ◽  
Chadwick L. Wright ◽  
...  
Keyword(s):  
Parathyroid Adenoma ◽  
Gamma Camera ◽  
Field Of View ◽  
Large Field ◽  
Time Saving ◽  
Valuable Adjunct ◽  
Parathyroid Hormone Monitoring ◽  
Parathyroid Adenomas ◽  
Portable Gamma Camera ◽  
The Mean

Background.We investigated a novel technique, intraoperative99 mTc-Sestamibi (MIBI) imaging (neck and excised specimen (ES)), using a large field-of-view portable gamma camera (LFOVGC), for expediting confirmation of MIBI-avid parathyroid adenoma removal.Methods.Twenty patients with MIBI-avid parathyroid adenomas were preoperatively administered MIBI and intraoperatively imaged prior to incision (neck) and immediately following resection (neck and/or ES). Preoperative and intraoperative serum parathyroid hormone monitoring (IOPTH) and pathology (path) were also performed.Results.MIBI neck activity was absent and specimen activity was present in 13/20 with imaging after initial ES removal. In the remaining 7/20 cases, residual neck activity and/or absent ES activity prompted excision of additional tissue, ultimately leading to complete hyperfunctioning tissue excision. Postexcision LFOVGC ES imaging confirmed parathyroid adenoma resection 100% when postresection imaging qualitatively had activity (ES) and/or no activity (neck). The mean ± SEM time saving using intraoperative LFOVGC data to confirm resection versus first IOPTH or path result would have been 22.0 ± 2 minutes (specimen imaging) and 26.0 ± 3 minutes (neck imaging).Conclusion.Utilization of a novel real-time intraoperative LFOVGC imaging approach can provide confirmation of MIBI-avid parathyroid adenoma removal appreciably faster than IOPTH and/or path and may provide a valuable adjunct to parathyroid surgery.

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