scholarly journals IN-VITRO SCREENING OF THEAFLAVIN AND GINKGETIN ON A549 LUNG CANCER CELL LINE

2020 ◽  
pp. 110-126
Author(s):  
Nisarg Vyas ◽  
Ram Tej Verma
Keyword(s):  
Cell Line ◽  
Cancer Cell Line ◽  
Cancer Chemoprevention ◽  
Lung Cancer Cell Line ◽  
A549 Lung Cancer Cell ◽  
Low Toxicity ◽  
Later Phase ◽  
Chick Embryo Model ◽  
A549 Lung

Cancer is a complex, multi-gene, multi-step disease occurring as a result of a sequential accumulation of genetic and epigenetic changes. Death due to cancer rank second among all cause of death globally. Dysregulation of signaling pathway e.g. HGF/c-MET which were otherwise activated during embryonic development contributes to malignant transformation and metastasis in later phase of life. Phytochemicals due to their safety, low toxicity, and general availability are either taken as supplement or through dietary sources for cancer chemoprevention or supportive agent during the treatment of cancer. The present study therefore aim to screen in-silico inspired c-MET antagonist Theaflavin & Ginkgetin in-vitro on against A549 cell line along with their antiangiogenesis effect on chick embryo model.

In vitro Cytotoxicity of Hibiscus sabdariffa Linn Extracts on A549 Lung Cancer Cell Line

2020 ◽  
Vol 12 (1) ◽  
pp. 14-19 ◽  
Author(s):  
Qotrunnada Fithrotunnisa ◽  
Ade Arsianti ◽  
Gerry Kurniawan ◽  
Fona Qorina ◽  
Nadzila Anindya Tejaputri ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Line ◽  
Cancer Cell Line ◽  
In Vitro Cytotoxicity ◽  
Lung Cancer Cell Line ◽  
Hibiscus Sabdariffa ◽  
Lung Cancer Cell ◽  
A549 Lung Cancer Cell ◽  
A549 Lung

The biosynthesis of a graphene oxide-based zinc oxide nanocomposite using Dalbergia latifolia leaf extract and its biological applications

2020 ◽  
Vol 44 (5) ◽  
pp. 2166-2179 ◽  
Author(s):  
Elavarasan Nagaraj ◽  
Prakash Shanmugam ◽  
Kokila Karuppannan ◽  
Thirunavukkarasu Chinnasamy ◽  
Sujatha Venugopal
Keyword(s):  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Antibacterial Activities ◽  
Lung Cancer Cell Line ◽  
Lung Cancer Cell ◽  
A549 Lung Cancer Cell ◽  
Line P ◽  
A549 Lung ◽  
Mcf 7

ZnO/GO nanocomposites were synthesized and their antibacterial activities assessed against various pathogens. They are potential antibacterial materials and significant anticancer activity against the MCF-7 breast cancer cell line compared to the A549 lung cancer cell line.

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