scholarly journals Atypical facial onset Guillain-Barré syndrome following first dose of COVISHIELD vaccine

2021 ◽  
Vol 20 (3) ◽  
pp. 379-382
Author(s):  
R.V. Aravinda ◽  
◽  
Priyanka Mahendra Tater ◽  
Harsha Huliyappa ◽  
Christy Joseph Manual ◽  
...  

In the midst of the global pandemic of COVID-19 and its significant morbidity and mortality reported across the world due to severe acute respiratory distress syndrome (SARS), it has always been posing a new set of complications each passing day. As we are still in the process of understanding about the complications related to COVID-19, we are encountered with complications related to immunization for COVID-19. We are reporting a case of facial onset Guillain-Barré syndrome (GBS) in the patient who received first dose of COVISHIELD vaccine a couple of weeks prior to the onset of his illness.

2022 ◽  
Vol 71 (6) ◽  
pp. 2254-55
Author(s):  
Seema Shafiq ◽  
Asim Riaz

Dear Editor, It is indeed an honour for us to contribute towards the ongoing research regarding the latest contagion, Coronavirus disease (COVID-19) as caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leading to global pandemic with variable clinical outcomes. COVID-19 positive individuals present with a variety of signs and symptoms as sore throat, cough, fever, dyspnoea, headache, myalgia, nausea, and vomiting whereas, some develop severe acute respiratory distress syndrome with a fatality rate of about 10%.1 Possible oral findings include xerostomia, hypogeusia, and chemosensory alterations. Common routes of transmission being person-to-person via direct sneeze, cough, and droplet inhalation or by contact through mucosa of eyes, nose and saliva.


2021 ◽  
Vol 2 (1) ◽  
pp. 1-4
Author(s):  
Krisna Yuarno Phatama ◽  
Sholahuddin Rhatomy, MD ◽  
Asep Santoso ◽  
Nicolaas C. Budhiparama

At the end of 2019, we faced a new variant of the coronavirus that can cause pneumonia and acute respiratory distress syndrome-like symptoms. It started in Wuhan, Hubei Province, China, and spread quickly to the whole world.This new virus is called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and can manifest as a disease called coronavirus disease 2019 (COVID-19). On March 13th, 2020 World Health Organization (WHO) declared COVID-19 as a global pandemic, and the story of frightening pandemic begin.


2021 ◽  
Vol 58 (2) ◽  
pp. 669-677
Author(s):  
Sarthak Katyal, Dr. Swarupa Chakole

Coronavirus is essentially a respiratory sickness brought about by a newfound rSARS-CoV-2 infection and distinguished in the city of Wuhan, China in December 2019. The emerging outbreak of Covid disease 2019 (COVID-19) brought about because ofthe severe respiratory disorder Covid 2 (SARS-CoV-2) presents a phenomenal test for medical services frameworks around the world.WHO has proclaimed this illness as a pandemic, and cautioned different nations. Like other Covids, this may create respiratory plot contaminations in the patients range from gentle to lethal ailment like pneumonia and ARDS(acute respiratory distress syndrome).The features of coronavirus and the capacity to quickly make far reaching contamination has significant ramifications, justifying vivacious disease avoidance and the preventive measures. While the affirmed quantity of the cases have outperformed 10.3 million throughout the world and keeps on developing, as the possible seriousness related to infection along  with its destructive confusions needs critical advancement of the novel restorative specialists to both forestall and cure the COVID-19 illness . In spite of the fact that antibodies and explicit medication treatments presently can't seem to be found, progressing investigation and subjective preliminaries have led to the examination of viability of the  reused medications for curing COVID-19 illness .According to the current audit, some of the medication competitors have been recommended to cure  COVID-19 will be talked about. While these incorporate enemy of the viral specialists (remdesivir ,rebetol, lopinavir-ritonavir,choloroquine, favipiravir, hydroxychloroquine, umifenovir ,oseltamivir,), immunomodulating based specialists (interferons, plasma bondings , tocilizumab), (azithromycin, corticosteroids),  along with other random specialists. With components of activity and further pharmacology based property which should be investigated, within a specific spotlight on the proof  base wellbeing with viability of a every specialist.


Author(s):  
Ghazaleh Khalili-Tanha ◽  
Majid Khazaei ◽  
Saman Soleimanpour ◽  
Gordon A Ferns ◽  
Amir Avan

Abstract: The outbreak of COVID-19 that began in Wuhan, China, has constituted a new emerging epidemic that has spread around the world. There are some reports on illustrated the patients getting reinfected after recovering from COVID-19. Here we provide an overview of the biphasic cycle of COVID-19, genetic diversity, immune response and chance of reinfection after recovering from COVID-19. The new generation of COVID-19 is highly contagious and pathogenic infection can lead to acute respiratory distress syndrome. Whilst most patients suffer from a mild form of the disease, there is a rising concern that patients who recover from COVID-19 may be at risk of reinfection. The proportion of the infected population, is increasing worldwide; meanwhile, the rate and concern of reinfection by the recovered population are still high. Moreover, there are a few evidence on the chance of COVID-19 infection even after vaccination, which is around one per cent or less. Although the hypothesis of zero reinfections after vaccination has not been clinically proven, further studies should be performed on the recovered class in clusters to study the progression of the exposed with the re-exposed subpopulations to estimate the possibilities of reinfection and, thereby, advocate the use of these antibodies for vaccine creation.


2020 ◽  
Vol 04 (01) ◽  
pp. 20-24
Author(s):  
Prachee Sathe ◽  
Vijay Sundar Singh

AbstractIn late 2019, China reported cases of respiratory illness in humans, which involved a novel Coronavirus SARS-CoV-2 (also known as 2019-nCoV). The World Health Organization (WHO) termed the disease COVID-19 (i.e., Coronavirus disease 2019). Most of the morbidity and mortality from COVID-19 is largely due to acute viral pneumonitis that leads to acute respiratory distress syndrome (ARDS). This article will discuss the clinical features of the multiorgan involvement in COVID-19 as well as the management of patients who become critically ill due to COVID-19.


2021 ◽  
Vol 0 ◽  
pp. 1-4
Author(s):  
Dawit Kebede Huluka ◽  
Sebrina Ahmed ◽  
Hiwotie Abebe ◽  
Joseph Huang ◽  
David H. Chong ◽  
...  

The COVID-19 pandemic is one of the largest health crises that the world has ever seen, infecting forty million people and killing more than 1 million to date. The disease has imposed a significant demand on health care resources due to the increased number and severely ill patients visiting facilities each day. Since there is no effective cure for COVID-19, supportive management with oxygen, steroids, anticoagulation, and prone positioning remains the major interventions. Prone ventilation is known to have a mortality benefit in intubated patients with acute respiratory distress syndrome (ARDS). However, studies on its role in intubated patients with COVID-19 ARDS (CARDS) are very scarce in resource-limited settings like Africa. We describe two patients with CARDS who were successfully treated with invasive mechanical ventilation, prone ventilation, and standard supportive care.


Author(s):  
Jundong Gu ◽  
Qinjun Zhao ◽  
Zhibo Han ◽  
Zhongchao Han

: The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) since Dec 2019, known as COVID-19 or 19-nCoV, has led to a major concern of the potential for not only an epidemic but a pandemic in China and now it seems to be a public health problem all over the world. The general mortality rate of the COVID-19 was about 3%. However, the mortality risk seems to be a significant increase in elderly and cases with chronic disease, who are more likely to develop into acute respiratory distress syndrome (ARDS). There still lacks effective methods for ARDS of COVID-19 patients and the prognosis was poor. Mesenchyma stem cells (MSCs) based treatment has the advantage of targeting numerous pathophysiological components of ARDS by secreting a series of cell factors, exerting anti-inflammatory, antioxidative, immunomodulatory, antiapoptotic, and proangiogenic effects, resulting in significant structural and functional recovery following ARDS in various preclinical models. And recently pilot clinical studies indicated MSCs based therapy was promise in treatment of ARDS caused by SARS-CoV-2. However, little is known about MSCs therapy for ARDS caused by COVID-19.


2021 ◽  
Vol 8 (4) ◽  
pp. 773
Author(s):  
Jade Irene Linardi

Coronavirus disease 2019 (COVID-19) as a global pandemic has become a major burden especially in the health care system and economy. COVID-19 has clinical presentations ranging from remain asymptomatic to severe acute respiratory distress syndrome (ARDS) and death. All age groups are susceptible to this virus, but it seems that children with COVID-19 have milder symptoms than adults. Neonates, however, have been reported to have more severe cases compared to older children. There is also a possibility of vertical transmission from mothers to their neonates which could not be ignored. This review provides current knowledge of COVID-19 in neonates.   


Author(s):  
Mesut Selamoğlu ◽  
Ali Raza Memon

The Corona Virus is the pandemic all over the world. This viral infection attacked all over the world like as disaster of viral infection which causes morbidity and mortality in different regions of world like Asia, Europe, and Africa etc. The different countries control the spread and complications of covid-19 like Acute Respiratory Distress Syndrome in well manner. In second wave there was again out break of covid-19 some regions of world. Here we discuss the causes of reoccurrence and their preventive measurements from our break effects of Covid-19.


2021 ◽  
Vol 5 (2) ◽  
pp. 113-126
Author(s):  
Vijay Singh ◽  
Shibu Sasidharan ◽  
Abdul Naseer ◽  
Harpreet Singh-Dhillon ◽  
Babitha Manalikuzhiyil ◽  
...  

The purpose of this review article is to analyse evidence on the use of ventilatory strategies and associated cointerventions in adult patients with COVID-19 induced acute respiratory distress syndrome (ARDS) and to provide treatment recommendations based on these interventions. For each recommendation mentioned, it is important to consider the quality of the evidence reviews thoroughly before applying these recommendations to specific clinical situations or policy decisions. No guideline or recommendations can consider all the compelling clinical features of individual patients, as they are unique. Thus, it is imperative that clinicians, patients, policy makers, and other stakeholders should not regard these recommendations as mandatory. However, this review article, impartially discusses the nuances of treatment available and management protocols followed in many centres around the world for the consumption of all treating physicians.


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