Assessment of Ankylosing Spondylitis Criteria in Patients with Chronic Low Back Pain and Vertebral Endplate Modic I Signal Changes

2010 ◽  
Vol 37 (11) ◽  
pp. 2334-2339 ◽  
Author(s):  
CHRISTELLE NGUYEN ◽  
IMAD BENDEDDOUCHE ◽  
KATHERINE SANCHEZ ◽  
MARYLÈNE JOUSSE ◽  
AGATHE PAPELARD ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Ankylosing Spondylitis ◽  
Chronic Low Back Pain ◽  
Tertiary Care ◽  
Low Back ◽  
Hla B27 ◽  
Vertebral Endplate ◽  
Mri Findings ◽  
Signal Changes

Objective.Patients with chronic low back pain (cLBP) and vertebral endplate Modic I signal changes on lumbar magnetic resonance imaging (MRI) have clinical features that could mimic inflammatory back pain related to spondyloarthritis (SpA) and/or ankylosing spondylitis (AS). We aimed to assess whether such patients fulfilled criteria for SpA and/or AS.Methods.For 5 months in 2008, all patients (n = 314) referred to a tertiary care physical medicine and rehabilitation facility in France were consecutively screened. A total of 185 hospitalized for non-specific cLBP were prospectively assessed. Forty patients fulfilling inclusion criteria were consecutively enrolled and included in 2 groups according to MRI findings: Modic I (n = 15) and non-Modic I (n = 25). MRI findings were assessed independently by 2 spine specialists and a radiologist. HLA-B27 status was determined. Data were collected on clinical measurements and fulfillment of Amor criteria (AC) and modified New York criteria (mNYC). All assessors were blinded to HLA-B27 status.Results.Whatever the Modic group, no patient fulfilled AC or mNYC, and mean total scores were comparable [3 ± 2 (range 0–22; p = 0.977), 1 ± 1 (range 0–3; p = 1.000), and 0 ± 0 (range 0–1; p = 1.000) for AC and clinical and radiological mNYC, respectively]. HLA-B27 status was similar in both groups [n = 2 (13%) vs n = 0 (0%); p = 0.135].Conclusion.Patients with cLBP and Modic I vertebral endplate signal changes on lumbar MRI do not fulfill widely used and validated criteria for SpA and/or AS. Such cases are clinically distinct from SpA and AS.

scholarly journals Pattern of Lumbar MRI Changes in Patients with Chronic Low Back Pain in a Tertiary Care Center

2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Rupesh Sharma ◽  
Awadhesh Tiwari ◽  
Rajeev Dwivedi
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Care Center ◽  
Tertiary Care ◽  
Low Back ◽  
Tertiary Care Center ◽  
Mri Findings ◽  
Common Cause ◽  
Mri Changes

Introduction: Chronic low back pain (LBP) is a common cause of disability worldwide. Magnetic resonance imaging (MRI) is an excellent non-invasive imaging modality for morphologic evaluation of the lumbar spine in patients with chronic low back pain because of its high contrast resolution and lack of ionizing radiation. This study was done to see the patterns of MRI changes in patients with chronic low back pain in a tertiary care center in Western Nepal. Methods: This was a cross-sectional study conducted on patients presenting with chronic low back pain. Eleven MRI parameters were noted and analyzed. Chi square test and Fisher’s Exact test were employed to see the associations between the various MRI findings. Results: A total of 108 patients were evaluated during the study period. MRI changes were noted in over 95% of the cases. Degenerative changes were the most common cause of low back pain, disc bulge being the most common MRI finding. A significant association was found between radiculopathy and decreased lumbar lordosis and vertebral endplate changes. Conclusion: MRI is an invaluable tool in the evaluation of chronic LBP because of its high resolution and lack of ionizing radiation. Significant MRI findings are noted in most of the cases of chronic LBP, degenerative changes being the most common and ranging from congenital to malignant lesions.

scholarly journals Assessment of Vitamin D Levels in Patients Presenting With Chronic Low Back Pain at a Tertiary Care Hospital

Cureus ◽  
2020 ◽  
Author(s):  
Mukesh Kumar ◽  
Masroor Ahmed ◽  
Ghulam Hussain ◽  
Muhammad Bux ◽  
Naveed Ahmed ◽  
...  
Keyword(s):  
Vitamin D ◽  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Low Back ◽  
Vitamin D Levels

scholarly journals ASSOCIATION OF LOW BACK PAIN AND SCIATICA WITH SIGNAL CHANGES IN THE VERTEBRAL ENDPLATE

2020 ◽  
Vol 19 (3) ◽  
pp. 213-217
Author(s):  
ALBERTO OFENHEJM GOTFRYD ◽  
DÉLIO EULÁLIO MARTINS FILHO ◽  
MARCELO WAJCHENBERG ◽  
MICHEL KANAS ◽  
SAULO DE TARSO DE SÁ PEREIRA SEGUNDO ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Type I ◽  
Low Back ◽  
Vertebral Endplate ◽  
Level Of Evidence ◽  
Signal Changes ◽  
Treatment Responses

ABSTRACT Objective To evaluate whether vertebral endplate signal changes (VESCs) influence the prognosis of patients submitted to conservative or surgical treatment for low back pain and lumbosciatica. Methods Study with 241 patients who underwent conservative treatment, infiltration or surgery with 12 months of follow-up. They were evaluated for pain by the Visual Analog Scale for Pain (VAS), for function by the Roland Morris questionnaire and for quality of life by the EuroQoI5 (EQ-5D). Results The VESCs did not have a significant effect on the treatment responses for the VAS (F = 0.03; P = 0.97), Roland Morris (F = 0.51; P = 0.60) and EQ-5D (F = 2.67; P = 0.07) variables, nor was there any interaction between VESC and treatment for VAS (F = 2.15; P = 0.08), Roland Morris (F = 1.55; P = 0.19) and EQ-5D (F = 2.15; P = 0.08). There was a significant effect for all treatments, however, the effect of the surgical procedure was superior when compared to the others (P <0.001). The VESC frequency was 48.33% for type 0, 29.17% for type I and 22.50% for type II. Conclusions The presence of VESC and its different types is not associated with a worse prognosis, nor was a higher prevalence of VESC observed in the patients with low back pain and lumbosciatica. Level of Evidence II; Retrospective cohort study.

scholarly journals Compensation of MRI findings in asymptomatic patients with chronic low back pain

2018 ◽  
pp. 141-146
Author(s):  
Levent ADIYEKE ◽  
Suavi Aydoğmuş ◽  
Özge Yapici Uğurlar ◽  
Tahir Mutlu Duymuş ◽  
Tolga Keçeci
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Low Back ◽  
Mri Findings ◽  
Asymptomatic Patients

scholarly journals High-sensitivity C-reactive protein in chronic low back pain with vertebral end-plate modic signal changes

2007 ◽  
Vol 57 (7) ◽  
pp. 1311-1315 ◽  
Author(s):  
François Rannou ◽  
Walid Ouanes ◽  
Isabelle Boutron ◽  
Bianca Lovisi ◽  
Fouad Fayad ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
High Sensitivity ◽  
Low Back ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
End Plate ◽  
Signal Changes

scholarly journals Osteitis CondensansIlii - A Rare Presentation

2017 ◽  
Vol 28 (2) ◽  
pp. 89-91
Author(s):  
Fauzia Sobhan ◽  
MSZ Khan ◽  
AKMAU Doza ◽  
Ameena Khandakar ◽  
MK Hassan
Keyword(s):  
Primary Care ◽  
Low Back Pain ◽  
Back Pain ◽  
Ankylosing Spondylitis ◽  
Chronic Low Back Pain ◽  
Primary Care Physicians ◽  
Inflammatory Arthritis ◽  
Unmarried Woman ◽  
Low Back ◽  
Rare Presentation

We presented a case of 45 years old unmarried woman who complaints of chronic low back pain and diagnosed as a case of Osteitis CondensansIlii (OCI). We are discussing this rare presentation of OCI to increase awareness among the specialty and primary care physicians, as it may be confused with other conditions like- Ankylosing Spondylitis (AS) and inflammatory arthritis. It also prevents misdiagnosis and extensive investigations that not only increase anxiety but are of little benefit.Medicine Today 2016 Vol.28(2): 89-91

scholarly journals Do Patients of Chronic Low Back Pain have Psychological Comorbidities?

2021 ◽  
Author(s):  
Kritika Singhal ◽  
Krishna Prasad Muliyala ◽  
Abhijit P. Pakhare ◽  
Prateek Behera ◽  
John Ashutosh Santoshi
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Sleep Quality ◽  
Chronic Low Back Pain ◽  
Tertiary Care ◽  
Hospital Setting ◽  
Low Back ◽  
Vas Score ◽  
Psychological Comorbidities ◽  
Anxiety Depression

Abstract Background Individuals with chronic pain have been reported to have an increased incidence of psychological morbidities. We aimed to examine the prevalence of anxiety, depression, disability, alexithymia, insomnia, and sleep quality in patients having chronic low back pain (LBP) and study their association with the severity of pain and any disability arising from it. Methods This descriptive study was conducted in a tertiary care teaching hospital setting. Fifty adults with nonspecific LBP of > 6-week duration were included. Study instruments employed were patient health questionnaire-9 for depression, generalized anxiety disorder-7 for anxiety, visual analogue scale (VAS) score for pain, Oswestry disability index (ODI) to assess disability, Toronto alexithymia scale-20 for alexithymia, and insomnia severity index and Pittsburgh sleep quality index for insomnia. Descriptive results were expressed as numbers, means, and proportions. Association study between variables was performed using Fisher’s exact test. Results Mean ODI score was 31.54% (95% CI, 26.09–36.99); mean VAS score was 6.08 (95% CI, 5.35–6.81). Insomnia of varying severity was found in 29 patients. Sleep quality was reported as good by 23 patients. One patient had alexithymia. There was significant association between the level of disability and depression, anxiety, insomnia, and sleep quality. The severity of pain had significant association with insomnia but the association with anxiety, depression, alexithymia, and sleep quality was not significant. Conclusions Patients with chronic LBP do have associated psychological comorbidities of varying extent. A “patient-centric” approach when treating patients with chronic LBP is necessary, so that appropriate evaluation of psychiatric and psychosocial comorbidities, sleep problems, and quality of life is done as part of their routine management to ensure the desired outcomes.

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