scholarly journals Discordance between ambulatory versus clinic blood pressure according to global cardiovascular risk group

2015 ◽  
Vol 30 (5) ◽  
pp. 610-619 ◽  
Author(s):  
Jinho Shin ◽  
Sung Ha Park ◽  
Ju Han Kim ◽  
Sang Hyun Ihm ◽  
Kwang-il Kim ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Risk Group ◽  
Clinic Blood Pressure ◽  
Global Cardiovascular Risk

scholarly journals Multiple Myeloma Patients Undergoing Carfilzomib: Development and Validation of a Risk Score for Cardiovascular Adverse Events Prediction

Cancers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1631
Author(s):  
Anna Astarita ◽  
Giulia Mingrone ◽  
Lorenzo Airale ◽  
Fabrizio Vallelonga ◽  
Michele Covella ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Risk Assessment ◽  
Multiple Myeloma ◽  
Cardiovascular Risk ◽  
High Risk ◽  
Adverse Events ◽  
Risk Score ◽  
Risk Group ◽  
High Risk Group ◽  
Cardiovascular Risk Assessment

Cardiovascular adverse events (CVAEs) are linked to Carfilzomib (CFZ) therapy in multiple myeloma (MM); however, no validated protocols on cardiovascular risk assessment are available. In this prospective study, the effectiveness of the European Myeloma Network protocol (EMN) in cardiovascular risk assessment was investigated, identifying major predictors of CVAEs. From January 2015 to March 2020, 116 MM patients who had indication for CFZ therapy underwent a baseline evaluation (including blood pressure measurements, echocardiography and arterial stiffness estimation) and were prospectively followed. The median age was 64.53 ± 8.42 years old, 56% male. Five baseline independent predictors of CVAEs were identified: office systolic blood pressure, 24-h blood pressure variability, left ventricular hypertrophy, pulse wave velocity value and global longitudinal strain. The resulting ‘CVAEs risk score’ distinguished a low- and a high-risk group, obtaining a negative predicting value for the high-risk group of 90%. 52 patients (44.9%) experienced one or more CVAEs: 17 (14.7%) had major and 45 (38.7%) had hypertension-related events. In conclusion, CVAEs are frequent and a specific management protocol is crucial. The EMN protocol and the risk score proved to be useful to estimate the baseline risk for CVAEs during CFZ therapy, allowing the identification of higher-risk patients.

scholarly journals Global Cardiovascular Risk Associated With Hypertension and Extent of Treatment and Control According to Risk Group

2012 ◽  
Vol 25 (5) ◽  
pp. 561-567 ◽  
Author(s):  
N. D. Wong ◽  
J. Dede ◽  
V. H. Chow ◽  
K. S. Wong ◽  
S. S. Franklin
Keyword(s):  
Cardiovascular Risk ◽  
Risk Group ◽  
Global Cardiovascular Risk ◽  
And Control

416 EFFECT OF A HIGH GLUCORAPHANIN BROCCOLI DIET ON BLOOD PRESSURE AND THE CARDIOVASCULAR RISK PROFILE OF AN AT RISK GROUP

2012 ◽  
Vol 30 ◽  
pp. e123 ◽  
Author(s):  
Charlotte N. Armah ◽  
Maria H. Traka ◽  
Jack R. Dainty ◽  
Joanne F. Doleman ◽  
John F. Potter ◽  
...  
Keyword(s):  
Blood Pressure ◽  
At Risk ◽  
Cardiovascular Risk ◽  
Risk Group ◽  
Risk Profile ◽  
Cardiovascular Risk Profile

Blood pressure and antihypertensive therapy according to the global cardiovascular risk level in Italy: the CHECK Study

2010 ◽  
Vol 17 (5) ◽  
pp. 562-568 ◽  
Author(s):  
Alessandro Filippi ◽  
Manuela Casula ◽  
Elena Tragni ◽  
Ovidio Brignoli ◽  
Claudio Cricelli ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Antihypertensive Therapy ◽  
Risk Level ◽  
Global Cardiovascular Risk

scholarly journals Enhanced blood pressure variability in a high cardiovascular risk group of African Americans: FIT4Life Study

2010 ◽  
Vol 4 (4) ◽  
pp. 187-195 ◽  
Author(s):  
Praveen Veerabhadrappa ◽  
Keith M. Diaz ◽  
Deborah L. Feairheller ◽  
Kathleen M. Sturgeon ◽  
Sheara Williamson ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
African Americans ◽  
Blood Pressure Variability ◽  
Risk Group ◽  
High Cardiovascular Risk

P635The addition of yoga to aerobic exercise programs reduces global cardiovascular risk

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
A Pandey ◽  
N Huq ◽  
M Chapman ◽  
A Fongang ◽  
P Poirer
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Cardiovascular Risk ◽  
Risk Score ◽  
Cardiovascular Event ◽  
Intervention Program ◽  
Organ Damage ◽  
Control Group ◽  
Global Cardiovascular Risk ◽  
End Organ Damage

Abstract Introduction Regular physical activity may modulate the inflammatory process and be cardio-protective. Yoga is a form of exercise that may have cardiovascular benefits. The effects of yoga on global cardiovascular risk have not been adequately described. The purpose of this study is to determine whether the addition of yoga to a regular exercise regimen reduces global cardiovascular risk. Methods Sixty consecutive individuals with essential hypertension were recruited in a lifestyle intervention program. All individuals with known hypertensive end organ damage, known cardiovascular diseases, as well as those taking medications/supplements that affected blood pressure, blood sugar, cholesterol or vascular inflammation were excluded. Participants were randomized to either a yoga group or similar duration stretching control group. Participants, over the 3-month intervention regimen, performed 15 minutes of either yoga or stretching in addition to 30 minutes of aerobic exercises thrice weekly. Blood pressure, cholesterol levels and hs-CRP were measured, and Reynold's Global Cardiovascular Risk Score was calculated at baseline and at the end of the 3-month intervention program. Results At screening, there were no statistically significant differences between the groups in any measured parameters or the 10-year risk of a cardiovascular event as measured by the Reynolds Risk Score. (8.2 vs. 9.0%; yoga vs. control group) After the 3-month intervention period, there was a statistically significantly greater decrease in the Reynold's Risk Score in the yoga vs. the control group. (7.0 vs. 8.4%, p=0.003, relative reduction 13.2 vs. 6.5%, p<0.0001) Baseline and 3 Month Outcomes Conclusions In patients with essential hypertension on no medications and with no known end organ damage, the practice of yoga incorporated into a 3-month exercise intervention program was associated with significant greater improvement in the Reynold's Risk of a 10-year cardiovascular event, when compared to the control stretching group. If these results are validated in more diverse populations over a longer duration of follow up, yoga may represent an important addition to traditional cardiovascular disease prevention programs.

Abstract WMP59: Premorbid Blood Pressure Control of Incident Transient Ischaemic Attacks and Strokes; Prevalence and Determinants; Analysis of Individual Patient Data over 10 Years

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Chamila Mettananda ◽  
Lixin Li ◽  
Gary Lau ◽  
Rose Wharton ◽  
Linda Bull ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
High Risk ◽  
Blood Pressure Control ◽  
Risk Group ◽  
Pressure Control ◽  
High Risk Group ◽  
High Risk Patients ◽  
Transient Ischaemic Attacks ◽  
Risk Patients

Background: Uncontrolled blood pressure is the most important modifiable risk factor for strokes. Aims and Methods: We determined the prevalence and determinants of blood pressure control in patients with incident transient ischaemic attacks(TIA) and strokes from 2002-2012 in a population-based cohort(Oxford Vascular Study). Controlled blood pressure(BP) was defined as having BP<140/90mmHg and was studied in different cardiovascular risk groups according to the Framingham 10-year general cardiovascular risk(CV-Risk) predicted at time of event and 10years pre-event; low(≤ 10%), moderate(11-19%) and high(≥ 20%) risk. We also studied the associations of controlled BP adjusted for age and sex. Results: Among 1741 patients with incident TIA/strokes, 1051 (60.4%) had known hypertension, of which 891 (84.8%) were on anti-hypertensive treatment. However, only 698 (40.1%) of all and 306 (29.1%) of treated patients had controlled BP. On predicted 10-year CV-Risk at event, 861 (72.5%) of 1188 (77.0%) in high risk group had known hypertension, of which 758 (88.0%) were on treatment. However, only 346 (29.1%) of all in high-risk group and 190 (25.1%) of treated high risk patients had controlled BP. In contrast, 120 (88.2%) of 136 (8.8%) in low risk group had controlled BP. Risk stratification without scoring for BP showed consistent results except the number in high-risk group dropped to 863 (55.9%). Analysis with CV-risk 10years pre-event also showed similar trends. Age(adjusted OR=0.97, 95%CI=0.97-0.98, p<0.001), high CV-risk at event/10years pre-event (0.97, 0.95-0.99, p<0.013, 0.95-0.99, p=0.008), being treated for hypertension(0.43, 0.35-0.52, p<0.001), BMI≥ 30Kg/m2(0.72, 0.55-0.92, p=0.010) and high total cholesterol(0.91, 0.84-0.99, p<0.026) were negatively associated with controlled BP. However history of atrial fibrillation(1.35, 1.03-1.77, p=0.030) and physical dependency(modified-Rankin-Scale>2; 1.54, 1.15-2.06, p<0.001) were positively associated with controlled BP. Conclusions: Premorbid blood pressure control in patients with incident TIA/strokes was inadequate especially in high-risk patients. Controlling BP to targets in elderly and high CV-risk patients would be important in reducing incident TIA/strokes.

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