The sound makes the difference: the utility of real time sound analysis for health monitoring in pigs

2013 ◽  
pp. 407-418
Author(s):  
S. Ferrari ◽  
M. Silva ◽  
V. Exadaktylos ◽  
D. Berckmans ◽  
M. Guarino
Keyword(s):  
Real Time ◽  
Health Monitoring ◽  
Sound Analysis ◽  
The Difference

scholarly journals A “Smart” Biosensor-Enabled Intravascular Catheter and Platform for Dynamic Delivery of Propofol to “Close the Loop” for Total Intravenous Anesthesia

2021 ◽  
Vol 186 (Supplement_1) ◽  
pp. 370-377
Author(s):  
Edward Chaum ◽  
Ernő Lindner
Keyword(s):  
Real Time ◽  
Drug Distribution ◽  
Population Based ◽  
Pharmacokinetic Data ◽  
Drug Infusion ◽  
Blood Concentrations ◽  
The Usa ◽  
The Difference ◽  
Automated Delivery

ABSTRACT Background Target-controlled infusion anesthesia is used worldwide to provide user-defined, stable, blood concentrations of propofol for sedation and anesthesia. The drug infusion is controlled by a microprocessor that uses population-based pharmacokinetic data and patient biometrics to estimate the required infusion rate to replace losses from the blood compartment due to drug distribution and metabolism. The objective of the research was to develop and validate a method to detect and quantify propofol levels in the blood, to improve the safety of propofol use, and to demonstrate a pathway for regulatory approval for its use in the USA. Methods We conceptualized and prototyped a novel “smart” biosensor-enabled intravenous catheter capable of quantifying propofol at physiologic levels in the blood, in real time. The clinical embodiment of the platform is comprised of a “smart” biosensor-enabled catheter prototype, a signal generation/detection readout display, and a driving electronics software. The biosensor was validated in vitro using a variety of electrochemical methods in both static and flow systems with biofluids, including blood. Results We present data demonstrating the experimental detection and quantification of propofol at sub-micromolar concentrations using this biosensor and method. Detection of the drug is rapid and stable with negligible biofouling due to the sensor coating. It shows a linear correlation with mass spectroscopy methods. An intuitive graphical user interface was developed to: (1) detect and quantify the propofol sensor signal, (2) determine the difference between targeted and actual propofol concentration, (3) communicate the variance in real time, and (4) use the output of the controller to drive drug delivery from an in-line syringe pump. The automated delivery and maintenance of propofol levels was demonstrated in a modeled benchtop “patient” applying the known pharmacokinetics of the drug using published algorithms. Conclusions We present a proof-of-concept and in vitro validation of accurate electrochemical quantification of propofol directly from the blood and the design and prototyping of a “smart,” indwelling, biosensor-enabled catheter and demonstrate feedback hardware and software architecture permitting accurate measurement of propofol in blood in real time. The controller platform is shown to permit autonomous, “closed-loop” delivery of the drug and maintenance of user-defined propofol levels in a dynamic flow model.

scholarly journals A Modified KNN Algorithm for High-Performance Computing on FPGA of Real-Time m-QAM Demodulators

Electronics ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 627
Author(s):  
David Marquez-Viloria ◽  
Luis Castano-Londono ◽  
Neil Guerrero-Gonzalez
Keyword(s):  
Real Time ◽  
High Performance ◽  
Interference Mitigation ◽  
Parallel Implementation ◽  
Computational Time ◽  
Successful Implementation ◽  
Interchannel Interference ◽  
The Difference ◽  
High Level ◽  
Performance Computing

A methodology for scalable and concurrent real-time implementation of highly recurrent algorithms is presented and experimentally validated using the AWS-FPGA. This paper presents a parallel implementation of a KNN algorithm focused on the m-QAM demodulators using high-level synthesis for fast prototyping, parameterization, and scalability of the design. The proposed design shows the successful implementation of the KNN algorithm for interchannel interference mitigation in a 3 × 16 Gbaud 16-QAM Nyquist WDM system. Additionally, we present a modified version of the KNN algorithm in which comparisons among data symbols are reduced by identifying the closest neighbor using the rule of the 8-connected clusters used for image processing. Real-time implementation of the modified KNN on a Xilinx Virtex UltraScale+ VU9P AWS-FPGA board was compared with the results obtained in previous work using the same data from the same experimental setup but offline DSP using Matlab. The results show that the difference is negligible below FEC limit. Additionally, the modified KNN shows a reduction of operations from 43 percent to 75 percent, depending on the symbol’s position in the constellation, achieving a reduction 47.25% reduction in total computational time for 100 K input symbols processed on 20 parallel cores compared to the KNN algorithm.

The feasibility and validity of using a real time location system (RTLS) to measure bedside contact time

2021 ◽  
pp. 174498712110161
Author(s):  
Ann-Marie Cannaby ◽  
Vanda Carter ◽  
Thomas Hoe ◽  
Stephenson Strobel ◽  
Elena Ashtari Tafti ◽  
...  
Keyword(s):  
Real Time ◽  
Contact Time ◽  
Measured Data ◽  
Complete Agreement ◽  
Observation Data ◽  
The Real ◽  
Measured Time ◽  
The Difference ◽  
Hospital Wards ◽  
Location Systems

Background The association between the nurse-to-patient ratio and patient outcomes has been extensively investigated. Real time location systems have the potential capability of measuring the actual amount of bedside contact patients receive. Aims This study aimed to determine the feasibility and accuracy of real time location systems as a measure of the amount of contact time that nurses spent in the patients’ bed space. Methods An exploratory, observational, feasibility study was designed to compare the accuracy of data collection between manual observation performed by a researcher and real time location systems data capture capability. Four nurses participated in the study, which took place in 2019 on two hospital wards. They were observed by a researcher while carrying out their work activities for a total of 230 minutes. The amount of time the nurses spent in the patients’ bed space was recorded in 10-minute blocks of time and the real time location systems data were extracted for the same nurse at the time of observation. Data were then analysed for the level of agreement between the observed and the real time location systems measured data, descriptively and graphically using a kernel density and a scatter plot. Results The difference (in minutes) between researcher observed and real time location systems measured data for the 23, 10-minute observation blocks ranged from zero (complete agreement) to 5 minutes. The mean difference between the researcher observed and real time location systems time in the patients’ bed space was one minute (10% of the time). On average, real time location systems measured time in the bed space was longer than the researcher observed time. Conclusions There were good levels of agreement between researcher observation and real time location systems data of the time nurses spend at the bedside. This study confirms that it is feasible to use real time location systems as an accurate measure of the amount of time nurses spend at the patients’ bedside.

scholarly journals Arrays of Conformable Ultrasonic Lamb Wave Transducers for Structural Health Monitoring with Real-time Electronics

2014 ◽  
Vol 87 ◽  
pp. 1266-1269 ◽  
Author(s):  
L. Capineri ◽  
A. Bulletti ◽  
M. Calzolai ◽  
P. Giannelli ◽  
D. Francesconi
Keyword(s):  
Structural Health Monitoring ◽  
Real Time ◽  
Health Monitoring ◽  
Lamb Wave ◽  
Structural Health

scholarly journals Traffic sensor health monitoring using spatiotemporal graphical modeling

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Linjiang Wu ◽  
Chao Liu ◽  
Tingting Huang ◽  
Anuj Sharma ◽  
Soumik Sarkar
Keyword(s):  
Health Status ◽  
Real Time ◽  
Sensor Network ◽  
Health Monitoring ◽  
Series Data ◽  
Spatiotemporal Pattern ◽  
Graphical Modeling ◽  
Traffic Sensors ◽  
Wide Range ◽  
Sensor Health

Accurate traffic sensor data is essential for traffic operation management systems and acquisition of real-time traffic surveillance data depends heavily on the reliability of the traffic sensors (e.g., wide range detector, automatic traffic recorder). Therefore, detecting the health status of the sensors in a traffic sensor network is critical for the departments of transportation as well as other public and private entities, especially in the circumstances where real-time decision is required. With the purpose of efficiently determining the sensor health status and identifying the failed sensor(s) in a timely manner, this paper proposes a graphical modeling approach called spatiotemporal pattern network (STPN). Traffic speed and volume measurement sensors are used in this paper to formulate and analyze the proposed sensor health monitoring system and historical time-series data from a network of traffic sensors on the Interstate 35 (I-35) within the state of Iowa is used for validation. Based on the validation results, we demonstrate that the proposed approach can: (i) extract spatiotemporal dependencies among the different sensors which leads to an efficient graphical representation of the sensor network in the information space, and (ii) distinguish and quantify a sensor issue by leveraging the extracted spatiotemporal relationship of the candidate sensor(s) to the other sensors in the network.

Sign in / Sign up

Export Citation Format

Share Document