Chronic Cocaine Abuse: Evidence for Adverse Effects on Health and Functioning

1984 ◽  
Vol 14 (10) ◽  
pp. 733-743 ◽  
Author(s):  
Arnold M Washton ◽  
Mark S Gold
Keyword(s):  
Adverse Effects ◽  
Cocaine Abuse ◽  
Chronic Cocaine

Adverse effects of cocaine abuse.

1984 ◽  
Author(s):  
Arnold M. Washton ◽  
Andrew Tatarsky
Keyword(s):  
Adverse Effects ◽  
Cocaine Abuse

scholarly journals Left ventricular hypertrophy associated with chronic cocaine abuse.

Circulation ◽  
1991 ◽  
Vol 84 (3) ◽  
pp. 1130-1135 ◽  
Author(s):  
M E Brickner ◽  
J E Willard ◽  
E J Eichhorn ◽  
J Black ◽  
P A Grayburn
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Cocaine Abuse ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Chronic Cocaine

scholarly journals Effects of Alcohol in Chronic Cocaine Abuse: A Follow Up Study

2016 ◽  
Vol 02 (01) ◽  
Author(s):  
Monica Rosselli ◽  
Chad Paul Simmers
Keyword(s):  
Cocaine Abuse ◽  
Follow Up Study ◽  
Chronic Cocaine

scholarly journals Dynamic interaction of genetic risk factors and cocaine abuse in the background of Parkinsonism – a case report

BMC Neurology ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Anett Illés ◽  
Péter Balicza ◽  
Viktor Molnár ◽  
Renáta Bencsik ◽  
István Szilvási ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Report ◽  
Dopamine Transporter ◽  
Environmental Risk ◽  
Cocaine Abuse ◽  
Environmental Risk Factors ◽  
Hand Tremor ◽  
Dopamine Transporter Imaging ◽  
Risk Variant ◽  
Chronic Cocaine

Abstract Background Parkinsonism is a complex multifactorial neurodegenerative disorder, in which genetic and environmental risk factors may both play a role. Among environmental risk factors cocaine was earlier ambiguously linked to Parkinsonism. Former single case reports described Parkinsonism in chronic cocaine users, but an epidemiological study did not confirm an increased risk of Parkinson’s disease. Here we report a patient, who developed Parkinsonism in young age after chronic cocaine use, in whom a homozygous LRRK2 risk variant was also detected. Case presentation The patient was investigated because of hand tremor, which started after a 1.5-year period of cocaine abuse. Neurological examination suggested Parkinsonism, and asymmetrical pathology was confirmed by the dopamine transporter imaging study. The genetic investigations revealed a homozygous risk allele in the LRRK2 gene. After a period of cocaine abstinence, the patient’s symptoms spontaneously regressed, and the dopamine transporter imaging also returned to near-normal. Conclusions This case report suggests that cocaine abuse indeed might be linked to secondary Parkinsonism and serves as an example of a potential gene-environmental interaction between the detected LRRK2 risk variant and cocaine abuse. The reversible nature of the DaTscan pathology is a unique feature of this case, and needs further evaluation, whether this is incidental or can be a feature of cocaine related Parkinsonism.

scholarly journals Dilated cardiomyopathy secondary to chronic cocaine abuse: a case report

2013 ◽  
Vol 6 (1) ◽  
pp. 536 ◽  
Author(s):  
Chad J Cooper ◽  
Sarmad Said ◽  
Haider Alkhateeb ◽  
Emmanuel Rodriguez ◽  
Remi Trien ◽  
...  
Keyword(s):  
Case Report ◽  
Dilated Cardiomyopathy ◽  
Cocaine Abuse ◽  
Chronic Cocaine

The Neuropsychiatry of Chronic Cocaine Abuse

1998 ◽  
Vol 10 (3) ◽  
pp. 280-289 ◽  
Author(s):  
Karen I. Bolla ◽  
Jean-Lud Cadet ◽  
Edythe D. London
Keyword(s):  
Cocaine Abuse ◽  
Chronic Cocaine
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