Multimodal Imaging Characterization of Arteriolosclerotic Plaques in Retinal Vein Occlusion

2021 ◽  
Vol 52 (12) ◽  
pp. 650-657
Author(s):  
Maria Vittoria Cicinelli ◽  
Saena Arifeen Sadiq ◽  
Shubhendu Mishra ◽  
Lee M. Jampol ◽  
Rukhsana G. Mirza
Keyword(s):  
Retinal Vein Occlusion ◽  
Multimodal Imaging ◽  
Vein Occlusion ◽  
Imaging Characterization

Multimodal imaging characterization of peripheral drusen

2020 ◽  
Vol 258 (3) ◽  
pp. 543-549
Author(s):  
Eleonora Corbelli ◽  
Enrico Borrelli ◽  
Mariacristina Parravano ◽  
Riccardo Sacconi ◽  
Marta Gilardi ◽  
...  
Keyword(s):  
Multimodal Imaging ◽  
Imaging Characterization

scholarly journals Characterization of microvascular tortuosity in retinal vein occlusion utilizing optical coherence tomography angiography

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Hyungwoo Lee ◽  
Myung Ae Kim ◽  
Hyung Chan Kim ◽  
Hyewon Chung
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Vein Occlusion ◽  
Optical Coherence Tomography Angiography ◽  
Branch Length ◽  
Optical Coherence ◽  
Branch Number ◽  
Affected Area ◽  
Vein Occlusion ◽  
Capillary Plexus

Abstract We investigated the characteristics of microvessel tortuosity in branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO) and their associations with visual outcomes using optical coherence tomography angiography (OCTA). Thirty-four BRVO and 21 CRVO patients and 31 healthy subjects were included. From OCTA, the branch number (BN), mean branch length (BL), mean Euclidean length (EL), vessel density (VD) and vessel tortuosity (VT) were quantified. In BRVO eyes, compared with that in the controls, the affected area of the deep capillary plexus (DCP) showed a decreased BN and VD, an increased BL, and unchanged VT. The nonaffected area of the DCP showed decreases in BN, VD and VT. The affected area of the superficial capillary plexus (SCP) showed higher VT. In CRVO eyes, the DCP showed a lower BN, VD and VT, while the SCP showed a lower BN and greater BL and EL. Improved visual acuity (VA) after 1 year in BRVO eyes was associated with decreases in BN, BL, VD and VT in the affected area in the DCP and lower VT in the nonaffected area of the SCP; in CRVO eyes, improved VA was associated with a higher BL and EL in the DCP. VT, BL, and EL may be new microvascular markers associated with changes in VA in BRVO and CRVO.

Multimodal Imaging Characterization of Intracardiac Thrombus and Myxoma

2008 ◽  
Vol 85 (6) ◽  
pp. 2162 ◽  
Author(s):  
Farzan Filsoufi ◽  
Joanna Chikwe ◽  
Javier G. Castillo ◽  
Javier Sanz
Keyword(s):  
Multimodal Imaging ◽  
Intracardiac Thrombus ◽  
Imaging Characterization

Multimodal imaging of two cases of retinal vein occlusion secondary to Waldenstrom macroglobulinemia

2021 ◽  
pp. 112067212199138
Author(s):  
Lidia Remolí Sargues ◽  
Javier Montero Hernández ◽  
Catalina Navarro Palop ◽  
Clara Monferrer Adsuara ◽  
Verónica Castro Navarro ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Vein Occlusion ◽  
Multimodal Imaging ◽  
Vision Loss ◽  
Optical Coherence ◽  
Waldenström Macroglobulinemia ◽  
Vein Occlusion ◽  
Waldenstrom Macroglobulinemia ◽  
Intravitreal Dexamethasone ◽  
Intraretinal Hemorrhages

Purpose: To report multimodal imaging characteristics of two cases of retinal vein occlusion (RVO) secondary to Waldenstrom macroglobulinemia (WM). Case report: Case 1: An 82-year-old woman presented with vision loss. She had a history of WM. Best-corrected visual acuity (BCVA) was 20/100 Snellen equivalent in the right eye (OD) and 20/63 in the left eye (OS). Fundoscopy showed bilateral hemorrhages in posterior pole and along superotemporal arcade. Fluorescein angiography illustrated no macular leakage. Optical coherence tomography (OCT) revealed macular edema (ME). Optical coherence tomography angiography (OCTA) demonstrated abnormalities in choriocapillaris. A diagnosis of bilateral branch RVO was made and ME was treated with intravitreal dexamethasone, achieving stability. Case 2: A 65-year-old man presented with venous dilation, tortuosity, and intraretinal hemorrhages. BCVA was 20/20 in both eyes (OU). OCT showed ME and hyperreflective dots in choroid. A diagnosis of bilateral central RVO was made. Laboratory evaluation and bone narrow biopsy confirmed a diagnosis of WM. After that, our patient consulted because of vision loss. BCVA was 20/400 in OU. Fundoscopy and OCT demonstrated a worsening of the intraretinal hemorrhages and the ME. OCTA showed damage of choriocapillaris. Thus, intravitreal dexamethasone and plasmapheresis was advised. Two months after, BCVA was 20/40 in the OD and 20/32 in the OS. Also, fundoscopy and OCT improved. Conclusion: Early treatment of WM is truly important, with the aim of achieving a decrease in IgM levels in order to avoid toxic effect over the RPE that results in refractory ME.

scholarly journals Multimodal Imaging of Microvascular Abnormalities in Retinal Vein Occlusion

2021 ◽  
Vol 10 (3) ◽  
pp. 405
Author(s):  
Yoshio Hirano ◽  
Norihiro Suzuki ◽  
Taneto Tomiyasu ◽  
Ryo Kurobe ◽  
Yusuke Yasuda ◽  
...  
Keyword(s):  
Retinal Vein Occlusion ◽  
Multimodal Imaging ◽  
Ex Vivo ◽  
Imaging Modalities ◽  
Retinal Layer ◽  
Vascular Networks ◽  
Vein Occlusion ◽  
High Resolution Images ◽  
Endothelial Growth Factor

The technologies of ocular imaging modalities such as optical coherence tomography (OCT) and OCT angiography (OCTA) have progressed remarkably. Of these in vivo imaging modalities, recently advanced OCT technology provides high-resolution images, e.g., histologic imaging, enabling anatomical analysis of each retinal layer, including the photoreceptor layers. Recently developed OCTA also visualizes the vascular networks three-dimensionally, which provides better understanding of the retinal deep capillary layer. In addition, ex vivo analysis using autologous aqueous or vitreous humor shows that inflammatory cytokine levels including vascular endothelial growth factor (VEGF) are elevated and correlated with the severity of macular edema (ME) in eyes with retinal vein occlusion (RVO). Furthermore, a combination of multiple modalities enables deeper understanding of the pathology. Regarding therapy, intravitreal injection of anti-VEGF drugs provides rapid resolution of ME and much better visual improvements than conventional treatments in eyes with RVO. Thus, the technologies of examination and treatment for managing eyes with RVO have progressed rapidly. In this paper, we review the multimodal imaging and therapeutic strategies for eyes with RVO with the hope that it provides better understanding of the pathology and leads to the development of new therapies.

scholarly journals Pediatric Central Retinal Vein Occlusion and Macular Edema Secondary to Isolated Retinal Racemose Hemangioma

2018 ◽  
Vol 3 (1) ◽  
pp. 45-48
Author(s):  
Omar Moinuddin ◽  
Matthew G. J. Trese ◽  
Cagri G. Besirli
Keyword(s):  
Macular Edema ◽  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Multimodal Imaging ◽  
Vision Loss ◽  
Late Complications ◽  
Vein Occlusion ◽  
Endothelial Growth Factor ◽  
Racemose Hemangioma ◽  
Central Retinal Vein

Isolated retinal racemose hemangioma is a rare disorder that may lead to vision loss due to late complications, most commonly central retinal vein occlusion (CRVO). We describe the longitudinal clinical course using multimodal imaging of a 13-year-old girl diagnosed with CRVO and macular edema in the setting of isolated retinal racemose hemangioma treated with intravitreal antivascular endothelial growth factor.

scholarly journals Multimodal Imaging of Cotton Wool Spots in Branch Retinal Vein Occlusion

2015 ◽  
Vol 54 (1) ◽  
pp. 48-56 ◽  
Author(s):  
Marion R. Munk ◽  
Gerlinde Matt ◽  
Magdalena Baratsits ◽  
Roman Dunavoelgyi ◽  
Wolfgang Huf ◽  
...  
Keyword(s):  
Retinal Vein Occlusion ◽  
Branch Retinal Vein Occlusion ◽  
Multimodal Imaging ◽  
Cotton Wool ◽  
Cotton Wool Spots ◽  
Vein Occlusion

Platelet Coagulant Activities and Retinal Vein Thrombosis

1977 ◽  
Vol 38 (02) ◽  
pp. 0399-0406 ◽  
Author(s):  
Peter N. Walsh ◽  
Richard E. Goldberg ◽  
Richard L. Tax ◽  
Larry E. Magargal
Keyword(s):  
Platelet Aggregation ◽  
Venous Thrombosis ◽  
Retinal Vein Occlusion ◽  
Serotonin Release ◽  
Platelet Factor ◽  
Trigger Mechanism ◽  
Local Conditions ◽  
Plasma Coagulation ◽  
Vein Thrombosis ◽  
Vein Occlusion

SummaryTo determine whether platelets play a role in the pathogenesis of retinal vein occlusion (RVO), platelets and coagulation were evaluated in 28 patients with RVO. Platelet coagulant activities concerned with the initiation and early stages of intrinsic coagulation were 2–4 fold increased in 9 patients with acute primary RVO but not in patients with acute secondary (10 patients) or chronic (9 patients) RVO. Platelet factor 3 activity, platelet aggregation, serotonin release by platelets and plasma coagulation were normal in all patients. Platelets may provide a trigger mechanism for venous thrombosis in the eye when local conditions permit.

Sign in / Sign up

Export Citation Format

Share Document