scholarly journals Role of Perfusion-Weighted Imaging in a Diffusion-Weighted-Imaging-Negative Transient Ischemic Attack

2017 ◽  
Vol 13 (2) ◽  
pp. 129 ◽  
Author(s):  
Sang Hun Lee ◽  
Hyun Wook Nah ◽  
Bum Joon Kim ◽  
Sung Ho Ahn ◽  
Jong S. Kim ◽  
...  
Keyword(s):  
Transient Ischemic Attack ◽  
Diffusion Weighted Imaging ◽  
Perfusion Weighted Imaging ◽  
Diffusion Weighted ◽  
Ischemic Attack

scholarly journals High‐resolution diffusion‐weighted imaging identifies ischemic lesions in a majority of transient ischemic attack patients

2019 ◽  
Vol 86 (3) ◽  
pp. 452-457 ◽  
Author(s):  
Benjamin Hotter ◽  
Ivana Galinovic ◽  
Claudia Kunze ◽  
Peter Brunecker ◽  
Gerhard J. Jungehulsing ◽  
...  
Keyword(s):  
High Resolution ◽  
Transient Ischemic Attack ◽  
Diffusion Weighted Imaging ◽  
Diffusion Weighted ◽  
Ischemic Attack

scholarly journals Optimal Timing of Diffusion-Weighted Imaging to Avoid False-Negative Findings in Patients With Transient Ischemic Attack

Stroke ◽  
2017 ◽  
Vol 48 (7) ◽  
pp. 1990-1992 ◽  
Author(s):  
Kenji Shono ◽  
Junichiro Satomi ◽  
Yoshiteru Tada ◽  
Yasuhisa Kanematsu ◽  
Nobuaki Yamamoto ◽  
...  
Keyword(s):  
Transient Ischemic Attack ◽  
Diffusion Weighted Imaging ◽  
False Negative ◽  
Optimal Timing ◽  
Diffusion Weighted ◽  
Negative Findings ◽  
Ischemic Attack

White matter hyperintensity volume predicts persistent cognitive impairment in transient ischemic attack and minor stroke

2016 ◽  
Vol 12 (3) ◽  
pp. 264-272 ◽  
Author(s):  
Leka Sivakumar ◽  
Parnian Riaz ◽  
Mahesh Kate ◽  
Thomas Jeerakathil ◽  
Christian Beaulieu ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
White Matter ◽  
Transient Ischemic Attack ◽  
Cognitive Assessment ◽  
Diffusion Weighted Imaging ◽  
Montreal Cognitive Assessment ◽  
White Matter Hyperintensity ◽  
Minor Stroke ◽  
Diffusion Weighted ◽  
Ischemic Attack

Background Temporary and permanent cognitive changes following transient ischemic attack/minor stroke have been described previously. It is unknown if persisting cognitive deficits in these patients are correlated with acute infarction identified using magnetic resonance imaging. Aims We tested the hypothesis that persistent cognitive impairment after transient ischemic attack/minor stroke can be predicted by the volume of diffusion-weighted imaging lesions. Methods Acute transient ischemic attack/minor stroke (NIH stroke scale score ≤ 3) patients were prospectively recruited within 72 h of onset. Patients underwent Montreal cognitive assessment and magnetic resonance imaging, including diffusion-weighted imaging and Fluid-Attenuated Inverse Recovery sequences, at baseline, days 7 and 30. Cognitive testing was repeated at day 90. Diffusion-weighted imaging lesion and Fluid-Attenuated Inverse Recovery chronic white matter hyperintensity volumes were measured planimetrically. Cognitive impairment was defined a priori as Montreal cognitive assessment score < 26. Results One hundred fifteen patients were imaged at a median (inter-quartile range) of 24.0 (16.6) h after onset. Acute ischemic lesions were present in 91 (79%) patients. Cognitive impairment rates were similar in patients with (47/91, 52%) and without diffusion-weighted imaging lesions (13/24, 54%; p = 0.83). Although linear regression indicated no relationship between acute diffusion-weighted imaging lesion volume and day 30 Montreal cognitive assessment scores (β = −0.163, [−2.243, 0.334], p = 0.144), white matter hyperintensity volumes at baseline were predictive of persistent cognitive deficits after 30 days (β = 2.24, [1.956, 45.369], p = 0.005). Conclusions In most transient ischemic attack/minor stroke patients who suffer acute cognitive impairment post event, deficits are temporary. Deficits after 30 days of onset are correlated with chronic white matter hyperintensity, suggesting subclinical cognitive impairment and/or impaired ability to compensate for the effects of acute ischemic infarcts.

Hyperacute Diffusion-Weighted Imaging Abnormalities in Transient Ischemic Attack Patients Signify Irreversible Ischemic Infarction

2005 ◽  
Vol 19 (6) ◽  
pp. 362-368 ◽  
Author(s):  
Yuichiro Inatomi ◽  
Kazumi Kimura ◽  
Toshiro Yonehara ◽  
Shodo Fujioka ◽  
Makoto Uchino
Keyword(s):  
Transient Ischemic Attack ◽  
Diffusion Weighted Imaging ◽  
Ischemic Infarction ◽  
Diffusion Weighted ◽  
Ischemic Attack

scholarly journals Higher Risk of Further Vascular Events Among Transient Ischemic Attack Patients With Diffusion-Weighted Imaging Acute Ischemic Lesions

Stroke ◽  
2004 ◽  
Vol 35 (10) ◽  
pp. 2313-2319 ◽  
Author(s):  
Francisco Purroy ◽  
Joan Montaner ◽  
Álex Rovira ◽  
Pilar Delgado ◽  
Manuel Quintana ◽  
...  
Keyword(s):  
Transient Ischemic Attack ◽  
Diffusion Weighted Imaging ◽  
Vascular Events ◽  
Diffusion Weighted ◽  
Ischemic Attack

scholarly journals Dual antiplatelet therapy reduced stroke risk in transient ischemic attack with positive diffusion weighted imaging

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Lu-lu Pei ◽  
Pei Chen ◽  
Hui Fang ◽  
Yuan Cao ◽  
Yi-nan Guo ◽  
...  
Keyword(s):  
High Risk ◽  
Antiplatelet Therapy ◽  
Transient Ischemic Attack ◽  
Diffusion Weighted Imaging ◽  
Stroke Risk ◽  
Proportional Hazards Model ◽  
Dual Antiplatelet Therapy ◽  
Cox Proportional Hazards Model ◽  
Diffusion Weighted ◽  
Ischemic Attack

Abstract Dual antiplatelet therapy (DAPT) reduced stroke risk in high-risk transient ischemic attack (TIA) patients assessed by ABCD2 score. Patients with positive diffusion-weighted imaging (DWI) were identified as imaging-based high-risk. The present study aims to investigate whether DAPT could reduce stroke risk in TIA with DWI positive. The study enrolled TIA patients within 72 h of onset from the prospective TIA database of the First Affiliated Hospital of Zhengzhou University. The predictive outcome was ischemic stroke at 90-day. The relationship between DAPT and stroke was analyzed in a cox proportional hazards model. The Kaplan–Meier curves of TIA patients with DAPT and monotherapy were plotted. Total of 661 TIA patients were enrolled, 279 of whom were DWI positive and 281 used DAPT. The 90-day stroke risk was higher in patients used monotherapy than those used DAPT in TIA with positive DWI (23.7% vs. 13.4%, p = 0.029). DAPT was associated with reduced stroke risk in TIA patients with positive DWI (hazard ratio [HR] = 0.54; 95% confidence interval [CI], 0.30–0.97; p = 0.037). However, the benefit didn’t exist in TIA patients with negative DWI (HR = 0.43; 95% CI, 0.14–1.33; p = 0.142). Early use of DAPT reduced stroke risk in TIA patients with positive DWI.

Sign in / Sign up

Export Citation Format

Share Document