Mechanism Study of Excess Sludge Disintegration by Stirred Ball Mill

2012 ◽  
Vol 518-523 ◽  
pp. 3403-3407 ◽  
Author(s):  
Jin Chi Liu ◽  
Tong Zhu ◽  
Jie Li ◽  
Zhan Min He ◽  
Yi Ming Zhang ◽  
...  
Keyword(s):  
Ball Mill ◽  
Large Scale ◽  
Mechanism Study ◽  
Excess Sludge ◽  
Disintegration Rate ◽  
Disintegration Time ◽  
Stirred Ball Mill

Stirred ball mill(SBM) method is one of the usually method which applied in large scale application cases of sludge disintegration. This study focuses on investigation the mechanism of sludge disintegration by SBM method. Besides analysis general indicators of SCOD, TN, TP and calculated the disintegration rate of COD (DDCOD). The result indicated the SCOD and DDCOD increased with the disintegration time. As DDCOD increased to the highest of 18.6% at the treated time of 60min, it shown that SBM was not more efficient in disintegration of biomass into so smaller particle that easily dissolved in water.

Anaerobic digestion and dewatering characteristics of mechanically disintegrated excess sludge

1997 ◽  
Vol 36 (11) ◽  
pp. 129-136 ◽  
Author(s):  
Julia Kopp ◽  
Johannes Müller ◽  
Norbert Dichtl ◽  
Jörg Schwedes
Keyword(s):  
Anaerobic Digestion ◽  
Ball Mill ◽  
Anaerobic Degradation ◽  
Excess Sludge ◽  
Particle Structure ◽  
Disintegration Rate ◽  
Digestion Time ◽  
Stirred Ball Mill ◽  
High Pressure Homogenizer ◽  
Cell Disintegration

Mechanical cell disintegration and its influence on anaerobic digestion was investigated using four different methods. Methods to describe the degree of cell-disruption were developed and the release of organic components into the sludge water was measured. The best results were optained using a stirred ball mill and a high-pressure homogenizer. The influence of disintegration rate and digestion time on the performance of the anaerobic process and the dewatering characteristics were investigated. The degradation is accelerated and the digestion time can be reduced, especially when using immobilised microorganisms. It could be shown that the mechanical disintegration results in a disruption of particle structure and an increase of polymer-demand. As a result of better anaerobic degradation the density and dewatering results of disintegrated sludges are improved in comparison to non-treated sludges.

scholarly journals Comparison of Some Physical Parameters of Whole and Scored Lisinopril and Lisinopril/Hydrochlorthiazide Tablets

2008 ◽  
Vol 8 (4) ◽  
pp. 391-395 ◽  
Author(s):  
Edina Vranić ◽  
Alija Uzunović
Keyword(s):  
Large Scale ◽  
Testing Procedure ◽  
Physical Parameters ◽  
Hardness Testing ◽  
Disintegration Time ◽  
Adequate Dose ◽  
Response Information ◽  
Tablet Splitting ◽  
Good Patient Compliance ◽  
Accepted Practice

Tablets are one of the most popular and preferred solid dosage forms because they can be accurately dosed, easily manufactured and packaged on a large scale, have good physical and chemical stability, and can contribute to good patient compliance given their ease of administration. The ability to match doses to patients depends on the availability of multiple dose sizes and adequate dose-response information. These are not always provided, so splitting of the tablets is sometimes necessary, Tablet splitting is an accepted practice in dispensing medication, It has been used when a dosage form of the required strength is not available commercially. The aim of our study was to compare some physical parameters of whole and scored lisinopril and lisinopril/hydrochlorthiazide tablets and to accept or exclude their influence on the obtaining of required dosage.According to the results obtained, we may conclude that tablets from batch “I” “IL “III” and “IV” satisfied pharmacopeial requirements concerning crushing strength, friability, disintegration time and mass uniformity. The hardness testing showed acceptable reproducibility and indicate that the data variation was primarily from the irreversible changes in the structure of tablet samples. The act of compacting powders stores energy within the tablets, by shifting or compressing the intermolecular bonds within the particles. The tablets have a natural tendency to relax once pressure is removed, and this tendency works against the interparticle bonding formed during compression. Hardness testing procedure causes irreversible changes in this structure.

Abstract 262: Derivation of Duchenne Muscular Dystrophy Disease Specific Cardiomyocytes From Patient Urine

2013 ◽  
Vol 113 (suppl_1) ◽  
Author(s):  
Xuan Guan ◽  
David L Mack ◽  
Claudia M Moreno ◽  
Fernando Santana ◽  
Charles E Murry ◽  
...  
Keyword(s):  
Stem Cells ◽  
Human Urine ◽  
Large Scale ◽  
Lentiviral Vector ◽  
Cellular Reprogramming ◽  
Urine Samples ◽  
Pcr Analysis ◽  
Scale Production ◽  
Mechanism Study

Introduction: Human somatic cells can be reprogrammed into primitive stem cells, termed induced pluripotent stem cells (iPSCs). These iPSCs can be extensively expanded in vitro and differentiated into multiple functional cell types, enabling faithful preservation of individual’s genotype and large scale production of disease targeted cellular components. These unique cellular reagents thus hold tremendous potential in disease mechanism study, drugs screening and cell replacement therapy. Due to the genetic mutation of the protein dystrophin, many DMD patients develop fatal cardiomyopathy with no effective treatment. The underlying pathogenesis has not been fully elucidated. Hypothesis: We tested the hypothesis that iPSCs could be generated from DMD patients’ urine samples and differentiated into cardiomyocytes, recapitulating the dystrophic phenotype. Methods: iPSCs generation was achieved by introducing a lentiviral vector expressing Oct4, Sox2, c-Myc and Klf4 into cells derived from patient’s (n=1) and healthy volunteers’ (n=3) urine. Cardiomyocytes were derived by sequentially treating iPSCs with GSK3 inhibitor CHIR99021 and Wnt inhibitor IWP4. Differentiated cardiomyocytes were subjected to calcium imaging, electrophysiology recording, Polymerase Chain Reaction (PCR) analysis, and immunostaining. Results: iPSCs were efficiently generated from human urine samples and further forced to differentiate into contracting cardiomyocytes. PCR analysis and immunostaining confirmed the expression of a panel of cardiac markers. Both normal and patient iPSC derived cardiomyocytes exhibited spontaneous and field stimulated calcium transients (up to 2Hz), as well as action potentials with ventricular-like and nodal-like characteristics. Anti-dystrophin antibodies stained normal iPSC-derived cardiomyocyte membranes but did not react against DMD iPSC-derived cardiomyocytes. Conclusions: Cardiomyocytes can be efficiently generated from human urine, through the cellular reprogramming technology. DMD cardiomyocytes retained the patient’s genetic information and manifested a dystrophin-null phenotype. Functional assessments are underway to determine differences that may exist between genotypes.

Breakage behavior of quartz in a laboratory stirred ball mill

1998 ◽  
Vol 100 (1) ◽  
pp. 69-73 ◽  
Author(s):  
Zhenhua Ma ◽  
Sian Hu ◽  
Shaoming Zhang ◽  
Xinzhang Pan
Keyword(s):  
Ball Mill ◽  
Stirred Ball Mill ◽  
Breakage Behavior

Effect of grinding aids on the grinding energy consumed during grinding of calcite in a stirred ball mill

2010 ◽  
Vol 23 (1) ◽  
pp. 54-57 ◽  
Author(s):  
H. Choi ◽  
W. Lee ◽  
D.U. Kim ◽  
S. Kumar ◽  
S.S. Kim ◽  
...  
Keyword(s):  
Ball Mill ◽  
Grinding Aids ◽  
Stirred Ball Mill
Sign in / Sign up

Export Citation Format

Share Document