Micro-Rocket System of Small Object Release Process Simulation

2014 ◽  
Vol 875-877 ◽  
pp. 994-997
Author(s):  
Ru Yi Tao ◽  
Yun Liu ◽  
Peng Li ◽  
Ming Huang
Keyword(s):  
Numerical Simulation ◽  
Process Simulation ◽  
Small Object ◽  
Release Process ◽  
Theoretical Methods ◽  
Object A ◽  
Solid Rocket ◽  
Release Model ◽  
Novel Model ◽  
Rocket System

To study the release process of micro-rocket system of small object, a novel model and numerical simulation is proposed. The structure and the work principle of the micro-rocket release system are explored. The release model is constructed using solid rocket theory, and including gap between objects and project canal. The theoretical methods are presented for the constructional design of micro-rocket releasing system of small object.

Dual Release Model to Evaluate Dissolution Profiles from Swellable Drug Polyelectrolyte Matrices

2020 ◽  
Vol 17 (6) ◽  
pp. 511-522 ◽  
Author(s):  
Alicia Graciela Cid ◽  
María Verónica Ramírez-Rigo ◽  
María Celeste Palena ◽  
Elio Emilio Gonzo ◽  
Alvaro Federico Jimenez-Kairuz ◽  
...  
Keyword(s):  
Experimental Data ◽  
Drug Release ◽  
Inflection Point ◽  
Release Profile ◽  
Experimental Point ◽  
Extended Model ◽  
Release Process ◽  
Proposed Model ◽  
Dual Release ◽  
Release Model

Background: Mathematical modeling in modified drug release is an important tool that allows predicting the release rate of drugs in their surrounding environment and elucidates the transport mechanisms involved in the process. Objective: The aim of this work was to develop a mathematical model that allows evaluating the release profile of drugs from polymeric carriers in which the swelling phenomenon is present. Methods: Swellable matrices based on ionic complexes of alginic acid or carboxymethylcellulose with ciprofloxacin were prepared and the effect of adding the polymer sodium salt on the swelling process and the drug release was evaluated. Experimental data from the ciprofloxacin release profiles were mathematically adjusted, considering the mechanisms involved in each stage of the release process. Results: A proposed model, named “Dual Release” model, was able to properly fit the experimental data of matrices presenting the swelling phenomenon, characterized by an inflection point in their release profile. This entails applying the extended model of Korsmeyer-Peppas to estimate the percentage of drug released from the first experimental point up to the inflection point and then a model called Lumped until the final time, allowing to adequately represent the complete range of the drug release profile. Different parameters of pharmaceutical relevance were calculated using the proposed model to compare the profiles of the studied matrices. Conclusion: The “Dual Release” model proposed in this article can be used to predict the behavior of complex systems in which different mechanisms are involved in the release process.

The Influence of Measured Trajectory Based Model Parameters Correcting on Simulation Precision of Power System Dynamic Frequency

2013 ◽  
Vol 448-453 ◽  
pp. 2545-2550
Author(s):  
Gang Mu ◽  
Ming Li ◽  
Jun An ◽  
Xing Wei Xu ◽  
Shuai Shao
Keyword(s):  
Numerical Simulation ◽  
Simulation Model ◽  
Process Simulation ◽  
Northeast China ◽  
Operation Mode ◽  
Measured Data ◽  
Model Parameters ◽  
Conservative Operation ◽  
Generator Frequency ◽  
Dynamic Frequency

Although numerical simulation is an important method of researching dynamic frequency process, obvious deviations have been found between numerical simulation and the measured trajectory in many accidents. And the existing simulation model and parameters cannot describe the actual dynamic process of frequency accurately. Research was carried out on the influence of four parameters to the dynamic frequency process, which based on the WSCC system. The four parameters include the inertia constant of generator, generator frequency coefficient, dead band and turbine intermediate superheating coefficient. Northeast China power grid and measured data are used to verify the above research conclusion. Checking the dynamic frequency process simulation model and parameters can improve the accuracy of dynamic frequency process simulation on the base of the measured trajectory and the physical characteristics of the parameters. It can also give efficient foundation for the setting work of UFLS, overcoming the previous conservative operation mode and so on.

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