Pathways to Improving Patient Safety and Reduced Cost: The Implementation of Clinical Effectiveness Guidelines for 2 Congenital Cardiac Anomalies

The relentless surges of global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections that caused the Covid-19 disease had pressured researchers and regulators to develop effective treatments quickly. While studying these therapies amid the pandemic, threats to patient care were reported, including (1) maintaining adequate safeguards as clinical effectiveness and safety data evolves, (2) risks from online counterfeit medications, and (3) disruption of the global pharmaceutical supply chain. This article discusses these patient safety threats and suggests strategies that promote patient safety, foster medication intelligence, and mitigate drug shortages. As the world continues to develop safe and effective treatments for Covid-19, patient safety is paramount. In response to the World Health Organization (WHO) Global Safety Challenge: Medication Without Harm, leaders must establish effective approaches to improve medication safety during the pandemic. Successfully integrating these leadership strategies with current practices allows pharmacy leaders to implement robust systems to reduce errors, prevent harm, and advocate for patient safety.

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Congenital cardiac anomalies and imperforate anus: A hospital's experience

Journal of Cardiovascular Disease Research ◽

10.1016/j.jcdr.2013.02.003 ◽

2013 ◽

Vol 4 (1) ◽

pp. 34-36 ◽

Cited By ~ 1

Author(s):

Jamal S. Kamal ◽

Ahmad S. Azhar

Keyword(s):

Imperforate Anus ◽

Cardiac Anomalies ◽

Congenital Cardiac Anomalies

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Primary versus Staged Closure of Exomphalos Major: Cardiac Anomalies Do Not Affect Outcome

European Journal of Pediatric Surgery ◽

10.1055/s-0037-1603088 ◽

2017 ◽

Vol 28 (03) ◽

pp. 279-284 ◽

Cited By ~ 2

Author(s):

Clare Rees ◽

Lucinda Tullie ◽

Agostino Pierro ◽

Edward Kiely ◽

Joe Curry ◽

...

Keyword(s):

Intensive Care ◽

Length Of Stay ◽

Primary Closure ◽

Single Center ◽

Fascial Defect ◽

Pentalogy Of Cantrell ◽

Cardiac Anomalies ◽

Intensive Care Stay ◽

Congenital Cardiac Anomalies ◽

Liver Herniation

Aim The objective of the study is to describe management of exomphalos major and investigate the effect of congenital cardiac anomalies. Methods A single-center retrospective review (with audit approval) was performed of neonates with exomphalos major (fascial defect ≥ 5cm ± liver herniation) between 2004 and 2014.Demographic and operative data were collected and outcomes compared between infants who had primary or staged closure. Data, median (range), were analyzed appropriately. Results A total of 22 patients were included, 20 with liver herniation and 1 with pentalogy of Cantrell. Gestational age was 38 (30–40) weeks, birth weight 2.7 (1.4–4.6) kg, and 13 (60%) were male. Two were managed conservatively due to severe comorbidities, 5 underwent primary closure, and 15 had application of Prolene (Ethicon Inc) mesh silo and serial reduction. Five died, including two managed conservatively, none primarily of the exomphalos. Survivors were followed up for 38 months (2–71). Cardiac anomalies were present in 20 (91%) patients: 8 had minor and 12 major anomalies. Twelve (55%) patients had other anomalies. Primary closure was associated with shorter length of stay (13 vs. 85 days, p = 0.02), but infants had similar lengths of intensive care stay, duration of parenteral feeds, and time to full feeds. Infants with cardiac anomalies had shorter times to full closure (28 vs. 62 days, p = 0.03), but other outcomes were similar. Conclusion Infants whose defect can be closed primarily have a shorter length of stay, but other outcomes are similar. Infants with more significant abdominovisceral disproportion are managed with staged closure; the presence of major cardiac anomalies does not affect surgical outcome.

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from imagination to reality: How much can interventional cardiologists do for congenital cardiac anomalies?

Catheterization and Cardiovascular Diagnosis ◽

10.1002/ccd.1810340312 ◽

1995 ◽

Vol 34 (1) ◽

pp. 46-47

Author(s):

Carlos E. Ruiz ◽

Ranae L. Larsen ◽

He Ping Zhang

Keyword(s):

Cardiac Anomalies ◽

Congenital Cardiac Anomalies

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Age of puppies at referral to veterinary cardiology specialists for murmur investigation

Acta Veterinaria Scandinavica ◽

10.1186/s13028-021-00603-0 ◽

2021 ◽

Vol 63 (1) ◽

Author(s):

Lynn Bernadette Rovroy ◽

Viktor Szatmári

Keyword(s):

Medical Records ◽

Digital Archive ◽

Cardiac Anomaly ◽

Time Interval ◽

Health Examination ◽

Cardiac Auscultation ◽

Congenital Cardiac Anomaly ◽

Cardiac Anomalies ◽

Veterinary Practitioner ◽

Congenital Cardiac Anomalies

Abstract Background Cardiac auscultation is an important screening test at the first health examination of puppies because most clinically relevant congenital cardiac anomalies cause a loud murmur from birth. This retrospective study aimed to investigate the age at which dogs with suspected congenital cardiac anomalies were referred to a veterinary cardiology specialist for murmur investigation. A secondary aim was to establish the time interval between the visit to the cardiologist and the first available murmur documentation. The digital archive of a veterinary teaching hospital was searched for dogs with congenital cardiac anomalies and puppies with innocent murmurs during a 5-year period. Dogs had to be referred because of a murmur, and they had to undergo physical examination and echocardiography by a veterinary cardiology specialist. The health certificate section of the pet passport, and the medical records from the referring veterinarian, were reviewed to identify the date when the murmur was first documented. Results Of the 271 included dogs, 94% had a congenital cardiac anomaly and 6% had an innocent murmur. The dogs’ median age was 190 days when they were examined by the cardiologist. Only 10% of the dogs were referred by the breeder’s veterinarian, while 90% of the dogs were referred by the new owner’s veterinarian. The median age of the first available murmur documentation by a first opinion veterinary practitioner was 95 days. Conclusions Only 10% of the puppies in the present study were referred to a veterinary cardiology specialist for murmur investigation before they were sold to a new owner. Referral prior to re-homing would have been feasible if the murmur had been detected and documented by the breeder’s veterinarian, if referral was offered by the breeder’s veterinarian and the referral was accepted by the breeder.

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ANGIOCARDIOGRAPHY IN INFANTS AND CHILDREN

PEDIATRICS ◽

10.1542/peds.6.1.20 ◽

1950 ◽

Vol 6 (1) ◽

pp. 20-32

Author(s):

JOHN D. KEITH ◽

JOHN D. MUNN

Keyword(s):

Infants And Children ◽

Newborn Period ◽

Cardiac Anomalies ◽

Congenital Cardiac Anomalies ◽

In Infants And Children

An apparatus is described which permits taking four roentgenograms/sec. Its use in angiocardiography is demonstrated by a series of cases with congenital cardiac anomalies. This method of investigation has proved most useful in studying the cyanotic group and in demonstrating shunts from right to left. A variety of different technics may, however, yield useful information in the noncyanotic group also. The procedures outlined are most valuable in the newborn period where congenital cardiac anomalies are so commonly encountered and where their differentiation is particularly difficult. The information collected in this manner has been, in many instances, a help to the surgeons in planning suitable surgery.

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