A cross sectional survey of adherence, perceived efficacy and side effects of methylphenidate among children at a teaching hospital in Sri Lanka

ObjectiveFollowing a switch from either a generic or branded antidepressant (venlafaxine) to a new generic, we investigated the factors associated with a preference for branded medicines, side effects reported following switching and efficacy ratings of the new generic drug.DesignA cross-sectional survey of patients switched to a new generic.SettingPatients accessing venlafaxine information online from the New Zealand government pharmaceuticals funding website.Participants310 patients, comprising 205 originally on branded venlafaxine and 105 previously taking a generic version.Main outcome measuresAn online questionnaire assessing demographic factors, perceived sensitivity to medicines, trust in pharmaceutical agencies, sources of switch information, preference for branded medicine, new medicine perceptions, side effects and efficacy ratings.ResultsPreference for branded medicine was significantly stronger in older patients (OR=1.04, 95% CI 1.01 to 1.05), those taking branded venlafaxine (OR=2.02, 95% CI 1.13 to 3.64) and patients with a higher perceived sensitivity to medicine (OR=1.23, 95% CI 1.06 to 1.19). Different factors predicted side effects in those switching from the branded and those switching from the generic venlafaxine. Trust in pharmaceutical agencies and the number of side effects were significant predictors of efficacy ratings of the new generic in both patients switching from a branded and those switching from a generic version of venlafaxine.ConclusionsIn patients switching from a branded medicine and those already taking a generic, different demographic and psychological factors are associated with preference for branded medicine, side effect reporting and perceived efficacy of the new drug. When switching to new generic, there appears to be a close bidirectional relationship between the experience of side effects and perceived drug efficacy. Trust in pharmaceutical agencies impacts directly on perceived efficacy and increasing such trust could reduce the nocebo response following a generic switch.

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Oxidative status in the β-thalassemia syndromes in Sri Lanka; a cross-sectional survey

Free Radical Biology and Medicine ◽

10.1016/j.freeradbiomed.2021.02.028 ◽

2021 ◽

Author(s):

Angela Allen ◽

Shiromi Perera ◽

Sachith Mettananda ◽

Rexan Rodrigo ◽

Lakshman Perera ◽

...

Keyword(s):

Sri Lanka ◽

Oxidative Status ◽

Cross Sectional Survey ◽

Cross Sectional

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Side effects following COVID-19 vaccination: A cross-sectional survey with age-related outcomes in Saudi Arabia

Journal Of Advanced Pharmacy Education And Research ◽

10.51847/1ufxsztr6m ◽

2021 ◽

Vol 11 (3) ◽

pp. 119-125

Author(s):

Ahlam Alghamdi ◽

Alnada Ibrahim ◽

Mohammed Alraey ◽

Afrah Alkazemi ◽

Isra Alghamdi ◽

...

Keyword(s):

Saudi Arabia ◽

Side Effects ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Age Related

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Medicinal plants’ use among patients with dyslipidemia: an Iranian cross-sectional survey

Journal of Complementary and Integrative Medicine ◽

10.1515/jcim-2018-0101 ◽

2018 ◽

Vol 16 (3) ◽

Cited By ~ 1

Author(s):

Mohammad Hashem Hashempur ◽

Seyed Hamdollah Mosavat ◽

Mojtaba Heydari ◽

Mesbah Shams

Keyword(s):

Side Effects ◽

Medicinal Plants ◽

Demographic Data ◽

Zingiber Officinale ◽

Cross Sectional Study ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Herbal Preparations ◽

Positive Effects ◽

High Prevalence

Abstract Background Despite growing demand for medicinal plants, there is little data about their use by patients with dyslipidemia. We aimed to determine the prevalence, pattern, and associated factors for the use of medicinal plants among patients with dyslipidemia. Methods A 17-item semi-structured questionnaire was filled out by 195 patients with dyslipidemia in a cross-sectional study carried out in two academic endocrinology clinics in Shiraz, Iran. The questionnaire comprised of three main domains of demographic data (6 questions), clinical data (2 of them), and data related to the use of medicinal plants (totally 9 questions). Results A total of 77.4% of patients took medicinal plants. The most common medicinal herbs used by dyslipidemic patients were Zataria multiflora, Cinnamomum zeylanicum, and Zingiber officinale. Duration of dyslipidemia was significantly longer in herbal users than non-herbal users (p=0.04). Patients believing that concomitant use of conventional drugs and herbal preparations had synergic positive effects in addition to those persuaded that herbal preparations possessed less side effects, were significantly more likely to use medicinal plants (p=0.008 and 0.005, respectively). Additionally, most of the medicinal herb users (87.4%) changed neither the pattern nor the dosage of their medications all during herbal preparations use. Conclusions This study demonstrated a high prevalence of medicinal plants’ use among patients with dyslipidemia, which was associated with the duration of dyslipidemia, patients’ viewpoints about herbal preparations’ synergic positive effects, and their fewer side effects.

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Patterns and perceived efficacy of herbal medicine for weight loss and maintenance: A cross-sectional survey from Jordan

European Journal of Integrative Medicine ◽

10.1016/j.eujim.2020.101086 ◽

2020 ◽

Vol 35 ◽

pp. 101086

Author(s):

Amal Akour ◽

Violet Kasabri ◽

Nailya Bulatova ◽

Suha Al Muhaissen ◽

Ruba Al Tarawneh ◽

...

Keyword(s):

Weight Loss ◽

Herbal Medicine ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Perceived Efficacy

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SEPTICEMIA;

The Professional Medical Journal ◽

10.29309/tpmj/2012.19.06.2465 ◽

2012 ◽

Vol 19 (06) ◽

pp. 808-811

Author(s):

SAEMA TEHSEEN ◽

AFIFA WAHEED ◽

NABEELA SHAMI

Keyword(s):

Study Design ◽

Teaching Hospital ◽

Public Awareness ◽

Developed Countries ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Number Of Patients ◽

Elective Termination ◽

Complete History ◽

Definite Role

Induced Miscarriage is defined as the elective termination of pregnancy before 24 weeks of gestation. Objectives: To determinethe frequency of sepsis associated with induced Miscarriage. Study Design: Cross-sectional survey. Setting: Department of Obstetrics andGynaecology, Unit-II, Ghurki Trust Teaching Hospital, Lahore. Duration of Study: Six months from 25-12-08 to 24-06-09. Materials andMethods: Total 110 cases were taken. Complete history including parity and mode of admission was taken. All information was recorded onspecially designed proforma. Results: A large number of patients turned out to be para 3-4 i.e. 87 (79%), 15 cases (13.7%) had the paritybetween 5-7 and only 8 cases (7.3%) were para 1-2 (Table-I).On analyzing the mode of admission it was found that 50 (45.4%) patients wereadmitted through out-patient department. 60 cases (54.6%) were admitted through emergency (Table-II). Finally the frequency of sepsisamongst women presenting with Miscarriage was calculated and it was found to be 25 (22.7%). 85 (77.3%) cases did not show any evidence ofsepsis (Table-III). Conclusions: Illegal Miscarriages are a major contribution to septic morbidity leading to a large number of maternal deathswhich is a dilemma in under developed countries like ours. Better public awareness and access to contraceptive measures has a definite role toplay in improving the outcome.

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Side Effects of mRNA-Based COVID-19 Vaccine: Nationwide Phase IV Study among Healthcare Workers in Slovakia

Pharmaceuticals ◽

10.3390/ph14090873 ◽

2021 ◽

Vol 14 (9) ◽

pp. 873

Author(s):

Abanoub Riad ◽

Barbora Hocková ◽

Lucia Kantorová ◽

Rastislav Slávik ◽

Lucia Spurná ◽

...

Keyword(s):

Side Effects ◽

Side Effect ◽

Healthcare Workers ◽

Large Scale ◽

Large Population ◽

Medical Attention ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Post Vaccination ◽

Phase Iv

mRNA-based COVID-19 vaccines such as BNT162b2 have recently been a target of anti-vaccination campaigns due to their novelty in the healthcare industry; nevertheless, these vaccines have exhibited excellent results in terms of efficacy and safety. As a consequence, they acquired the first approvals from drug regulators and were deployed at a large scale among priority groups, including healthcare workers. This phase IV study was designed as a nationwide cross-sectional survey to evaluate the post-vaccination side effects among healthcare workers in Slovakia. The study used a validated self-administered questionnaire that inquired about participants’ demographic information, medical anamneses, COVID-19-related anamnesis, and local, systemic, oral, and skin-related side effects following receiving the BNT162b2 vaccine. A total of 522 participants were included in this study, of whom 77% were females, 55.7% were aged between 31 and 54 years, and 41.6% were from Banska Bystrica. Most of the participants (91.6%) reported at least one side effect. Injection site pain (85.2%) was the most common local side effect, while fatigue (54.2%), headache (34.3%), muscle pain (28.4%), and chills (26.4%) were the most common systemic side effects. The reported side effects were of a mild nature (99.6%) that did not require medical attention and a short duration, as most of them (90.4%) were resolved within three days. Females and young adults were more likely to report post-vaccination side effects; such a finding is also consistent with what was previously reported by other phase IV studies worldwide. The role of chronic illnesses and medical treatments in post-vaccination side effect incidence and intensity requires further robust investigation among large population groups.

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Knowledge, Attitude & Practice Among Psoriasis Patients in India Towards Teledermatology During COVID-19 Pandemic

Dermatology and Dermatitis ◽

10.31579/2578-8949/088 ◽

2021 ◽

Vol 6 (4) ◽

pp. 01-13

Author(s):

Archana Mavoori ◽

Sudha Bala ◽

Rajiv Kumar Bandaru ◽

Aruna Kumari Yerra

Keyword(s):

Teaching Hospital ◽

Tertiary Care ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Tertiary Care Teaching Hospital ◽

Care Teaching ◽

Attitude And Practice ◽

Knowledge And Attitude ◽

Knowledge Attitude And Practice

Background: The current COVID-19 pandemic has imposed upon the entire community norms of social distancing and home quarantine. Follow up consultations in these times can be made through teledermatology through smart phones. Success of this technology in these hours of crisis depends upon the knowledge, attitude and behaviour of patients towards teledermatology. Follow up consultations done through teleconsultations will decrease risk of exposure to COVID-19 among psoriasis patients who need frequent follow ups. Aim: The main objective of this study is to assess the awareness, knowledge, attitude and practice of teledermatology through teledermatology among psoriasis patients at a tertiary care teaching hospital. Materials and Methods: A cross-sectional survey, from Psoriasis Clinic registry maintained in the outpatient department of DVL of a tertiary care teaching hospital in India is conducted. A pre-validated self-administered questionnaire is used for the survey to assess knowledge, attitude and practice of teledermatology. Analysis will be done as per study objectives using descriptive statistics for quantitative data and content analysis for qualitative data. Results: Out of 150 patients, 87(58%) were males and females were 63(42%). Most common age group to participate in the study was 36-45 years- 43(28.7%). Majority of participants were educated up to –graduate 53(35.3%). Males had higher knowledge and attitude scores compared to females. Most of the patients found using teleconsutations easy and convenient. Conclusion: Teledermatology is the need of the hour to be implemented in these hours of COVID-19 pandemic.

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FACTORS AFFECTING ADHERENCE TO RECOMMENDED MEDICATIONS AMONG PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) IN A SELECTED TEACHING HOSPITAL, SRI LANKA

International Journal of Research -GRANTHAALAYAH ◽

10.29121/granthaalayah.v7.i9.2019.553 ◽

2020 ◽

Vol 7 (9) ◽

pp. 16-29

Author(s):

I.M.M. Dassanayaka ◽

K.K.V.P. Dayananda ◽

Thamara D. Amarasekara

Keyword(s):

Sri Lanka ◽

Teaching Hospital ◽

Electronic Device ◽

Binary Logistic Regression ◽

Chronic Obstructive ◽

Binary Logistic Regression Analysis ◽

Cross Sectional ◽

Obstructive Pulmonary Disease ◽

Factors Affecting ◽

Drug Classes

Background: This study was conducted to determine the prevalence of adherence and factors affecting adherence to recommended medications among patients with COPD in a selected teaching hospital, Sri Lanka. Method: A descriptive cross-sectional design was used among conveniently selected (n=184) participants who attended to the Colombo South Teaching Hospital, Sri Lanka. Data were collected using a pre-tested (n=10) interviewer-administered questionnaire and Morisky Green Levine Scale from January to March 2019. Results: Most of the participants were male (108, 58.7%) and above 65 years old (108, 58.7%). Among all participants, 121 (65.8%) adhered to the recommended medications for COPD, and 63 participants (34.2%) were non-adhered. Demographic factors were not associated with adherence. Number of prescribed respiratory drug classes, number of respiratory medication on the last prescription, number of doses per day, vaccination (pneumococcal, influenza), using an electronic device to remember the time of administering medicine, (p<0.05) were significantly associated with adherence. According to the binary logistic regression analysis, clear and understandable written instructions in dispensing label (p<0.05) were significantly associated with adherence. Conclusions: Most of the participants adhered to the recommended medications for COPD. Health education interventions might enhance the sustainability of adherence to recommended medication among patients with COPD.

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Healthcare personnel knowledge, motivations, concerns and intentions regarding COVID-19 vaccines: a cross-sectional survey

10.1101/2021.02.19.21251993 ◽

2021 ◽

Author(s):

Vivek Jain ◽

Sarah B. Doernberg ◽

Marisa Holubar ◽

Beatrice Huang ◽

Carina Marquez ◽

...

Keyword(s):

Side Effects ◽

San Francisco ◽

Vaccine Uptake ◽

Healthcare Personnel ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Adult Age ◽

Raising Awareness ◽

Few Data ◽

The University

AbstractBackgroundHealthcare personnel (HCP) are prioritized for earliest SARS-CoV-2 vaccine administration, yet relatively few data exist on HCP’s knowledge, motivations, concerns, and intentions regarding COVID-19 vaccines.MethodsWe conducted a cross-sectional survey Nov.16-Dec.8, 2020 among HCP enrolled in a cohort study at three Northern California medical centers serving diverse roles including COVID-19 patient care. Eligible HCP were adult (age≥18) on-site employees of the University of California, San Francisco, San Francisco General Hospital, and Stanford Healthcare. A one-time electronically-administered survey was sent to cohort HCP on November 16, 2020 and responses analyzed.ResultsOverall, among 2,448 HCP invited, 2,135 completed the COVID-19 vaccine survey (87.2% response rate). HCPs had mean age 41 years, were 73% female, and had diverse jobs including COVID-19 patient contact. Enthusiasm for vaccination was overall strong, and more HCP (1,453, 69%) said they would definitely/likely receive vaccine if formally FDA-approved versus if approved via emergency use authorization only (785, 35%). While 541 (25%) respondents wanted to be among the earliest to receive vaccine, more desired vaccination after the first round (777, 36%) or >2 months after vaccinations began (389, 18%). Top factors increasing motivation for vaccination included perceiving risk from COVID-19 to self (1,382, 65%) or to family/friends (1355, 63%). Top concerns were vaccine side effects, cited by 596 (28%), and concerns about political involvement in FDA’s approval process (249, 12%).ConclusionsHCP were enthusiastic about COVID-19 vaccination for individual protection and protecting others, but harbored concerns about vaccine side effects. Our data may inform emerging vaccine education campaigns.Key PointsAmong 2,135 healthcare personnel surveyed, we found enthusiasm for COVID-19 vaccination both for individual benefit and protecting others. However, healthcare personnel rated their knowledge of COVID-19 vaccines as only moderate and harbored concerns about vaccine side effects. Education raising awareness of vaccine efficacy and side effects may help maximize vaccine uptake.

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