Effects of Chromium Picolinate Supplementation on Growth Performance, Small Intestine Morphology and Antioxidant Status in Ducks Under Heat Stress Conditions

This study aimed to investigate the effects of dietary fumaric acid (FA) on growth performance, immune responses, immune organ index and antioxidant status in broilers under chronic heat stress (HS). A total of 200 21-day-old Ross 308 chicks were randomly assigned in a 2 × 2 factorial arrangement with two diets (basal diet or 10 g/kg FA diet) and two temperatures (thermoneutral or HS) for 21 days. On day 42, growth performance, immune organ index, immune function and antioxidative ability were determined. HS resulted in a significant reduction in final body weight (FBW), average daily feed intake (ADFI), average daily gain (ADG), antibody titres against sheep red blood cells (SRBC) and Newcastle disease virus, IgM, IgG, relative weights of spleen, thymus and bursa of Fabricius, but a significant increase in the feed conversion ratio (FCR), activities of total superoxide dismutase (T-SOD) and glutathione peroxidase (GPx) in the bursa, contents of malondialdehyde and total carbonyl (TC) in thymus and bursa (P < 0.05). Dietary supplementation of FA increased FBW, ADFI, ADG, antibody titres against SRBC, IgG, relative weights of spleen and bursa, activity of GPx in thymus and bursa, whereas it decreased the FCR and TC of thymus and bursa. These results suggest that dietary 10 g/kg FA had positive effects on growth performance and immune function through improving the antioxidative capacity of immune organs.

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Chronic heat stress regulates the relation between heat shock protein and immunity in broiler small intestine

Scientific Reports ◽

10.1038/s41598-020-75885-x ◽

2020 ◽

Vol 10 (1) ◽

Cited By ~ 1

Author(s):

Sharif Hasan Siddiqui ◽

Darae Kang ◽

Jinryong Park ◽

Mousumee Khan ◽

Kwanseob Shim

Keyword(s):

Body Weight ◽

Small Intestine ◽

Heat Stress ◽

Treatment Group ◽

Heat Shock ◽

Heat Shock Protein ◽

Growth Performance ◽

Control Group ◽

Immune Functions ◽

Negative Effect

Abstract Chronic heat stress is considered to decrease the immune functions which makes negative effect on broiler growth performance. Here, we investigated the relationship between chronic heat stress, growth performance, and immunity in the small intestine of broilers. The study included two groups (control and heat stressed group) with eight replications per group. Ten broilers of 20-day aged were allocated in each replication. On day 35, the treatment group was subdivided into two groups based on their body weights (heavy and low body weight). Although, there was only the control and treatment group on day 28. The growth performance decreased and expression of heat shock protein 70 (HSP70), HSP60, and HSP47 increased on days 28 and 35 in the chronic heat stress group as compared with those in the control group. The expression levels of HSPs were significantly higher in the low body weight group than in the control group. The genes HSP70 and HSP60 were significantly associated with pro- and anti-inflammatory cytokines in the small intestine of the broilers of the treatment group. Thus, HSP70 and HSP60 activated the adaptive immunity in the small intestines of the broilers from the treatment group to allow adaptation to chronic heat stress environment.

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