Left Is Not Right – Callosal Disconnection Syndrome

2021 ◽  
Vol 69 (4) ◽  
pp. 1142
Author(s):  
Jidhin Raj ◽  
Jacob George ◽  
Neethu Suresh ◽  
Ajay Radhakrishnan
Keyword(s):  
Disconnection Syndrome

scholarly journals The Role of White Matter Disconnection in the Symptoms Relating to the Anarchic Hand Syndrome: A Single Case Study

2021 ◽  
Vol 11 (5) ◽  
pp. 632
Author(s):  
Valentina Pacella ◽  
Giuseppe Kenneth Ricciardi ◽  
Silvia Bonadiman ◽  
Elisabetta Verzini ◽  
Federica Faraoni ◽  
...  
Keyword(s):  
White Matter ◽  
Single Case ◽  
Brain Lesion ◽  
Structural Connectivity ◽  
Disconnection Syndrome ◽  
Neuroimaging Data ◽  
Neuropsychological Investigation ◽  
Anterior Posterior

The anarchic hand syndrome refers to an inability to control the movements of one’s own hand, which acts as if it has a will of its own. The symptoms may differ depending on whether the brain lesion is anterior, posterior, callosal or subcortical, but the relative classifications are not conclusive. This study investigates the role of white matter disconnections in a patient whose symptoms are inconsistent with the mapping of the lesion site. A repeated neuropsychological investigation was associated with a review of the literature on the topic to identify the frequency of various different symptoms relating to this syndrome. Furthermore, an analysis of the neuroimaging regarding structural connectivity allowed us to investigate the grey matter lesions and white matter disconnections. The results indicated that some of the patient’s symptoms were associated with structures that, although not directly damaged, were dysfunctional due to a disconnection in their networks. This suggests that the anarchic hand may be considered as a disconnection syndrome involving the integration of multiple antero-posterior, insular and interhemispheric networks. In order to comprehend this rare syndrome better, the clinical and neuroimaging data need to be integrated with the clinical reports available in the literature on this topic.

Dysexecutive behaviour following deep brain lesions – A different type of disconnection syndrome?

Cortex ◽  
2012 ◽  
Vol 48 (1) ◽  
pp. 97-119 ◽  
Author(s):  
Martin Krause ◽  
Neil Mahant ◽  
Katya Kotschet ◽  
Victor S. Fung ◽  
Daniel Vagg ◽  
...  
Keyword(s):  
Brain Lesions ◽  
Disconnection Syndrome ◽  
Deep Brain

Callosal disconnection syndrome after ischemic stroke of the corpus callosum due to meningococcal meningitis: A case report

2016 ◽  
Vol 369 ◽  
pp. 119-120 ◽  
Author(s):  
Nicola A. Marchi ◽  
Radek Ptak ◽  
Corinne Wetzel ◽  
Maria I. Vargas ◽  
Armin Schnider ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Case Report ◽  
Corpus Callosum ◽  
Meningococcal Meningitis ◽  
Disconnection Syndrome

Improvement in callosal disconnection syndrome with recovery of callosal connectivity

Neurocase ◽  
2021 ◽  
pp. 1-9
Author(s):  
Keisuke Morihara ◽  
Kazuo Kakinuma ◽  
Erena Kobayashi ◽  
Nobuko Kawakami ◽  
Wataru Narita ◽  
...  
Keyword(s):  
Disconnection Syndrome

Abstract 1122‐000205: Bilateral ACA Stroke ‐ A Case Report of an Unusual Presentation

2021 ◽  
Vol 1 (S1) ◽  
Author(s):  
Tejeswi Suryadevara ◽  
Bhavya Narapureddy ◽  
Carlos Y Lopez ◽  
Karen C Albright
Keyword(s):  
Case Report ◽  
Brain Magnetic Resonance Imaging ◽  
Whole Body ◽  
Rapid Improvement ◽  
Stroke Registry ◽  
Disconnection Syndrome ◽  
Leg Weakness ◽  
Anatomic Variants ◽  
Computed Tomography Angiogram ◽  
Cerebrovascular Risk

Introduction : Bilateral ACA strokes are rare, with one stroke registry reporting 2 cases out of 1490 strokes (1). These strokes are even less common in the absence of anatomic variants, such as an azygos ACA. Diagnosis may be difficult given the variability in clinical presentation. Methods : This is a case report. Results : A 51‐year‐old right handed man with no cerebrovascular risk factors on no antithrombotic medications presented two hours from last known well with complaints of generalized weakness, inability to speak or move, and feeling numb all‐over during intercourse. He reported rapid improvement in symptoms. Emergency room exam was notable for right leg weakness (3/5) and left leg plegia with intact sensation. Hoover’s sign was positive in the left leg and the patient was able to bear some weight while standing with a two‐person assist. A computed tomography angiogram (CTA) of his head and neck was preliminarily interpreted as normal. No azygos ACA or single internal carotid artery origin for the ACAs were present. His exam improved to an isolated left foot dorsiflexor and plantar flexor weakness. The decision was made not to use thrombolytics based on his symptoms and exam which were improving and not entirely consistent with acute stroke. Brain magnetic resonance imaging demonstrated bilateral parasagittal acute strokes. It was later noted the that non‐contrast head CT demonstrated bilateral hyperdense ACAs. Conclusions : This case demonstrates the difficulty in diagnosing bilateral ACA infarcts in a previously healthy adult in the setting of whole‐body numbness and positive Hoover’s sign. In retrospect, his transient inability to speak or move may have been transient akinetic mutism or callosal disconnection syndrome. Additionally, this case emphasizes the importance of evaluating for the hyperdense ACA sign (2) in patients complaining of bilateral leg weakness.

Absence of Disconnection Syndrome after Early Callosotomy

1995 ◽  
pp. 225-240 ◽  
Author(s):  
Maryse Lassonde ◽  
Hannelore Sauerwein ◽  
Guy Geoffroy ◽  
Claude Mercier
Keyword(s):  
Disconnection Syndrome

scholarly journals The Role of White Matter Disconnection in the Symptoms Relating to the Anarchic Hand Syndrome: A Single Case Study

2021 ◽  
Author(s):  
Valentina Pacella ◽  
Giuseppe Kenneth Ricciardi ◽  
Silvia Bonadiman ◽  
Elisabetta Verzini ◽  
Federica Faraoni ◽  
...  
Keyword(s):  
White Matter ◽  
Single Case ◽  
Brain Lesion ◽  
Structural Connectivity ◽  
Disconnection Syndrome ◽  
Neuroimaging Data ◽  
Neuropsychological Investigation ◽  
Anterior Posterior

The anarchic hand syndrome refers to an inability to control the movements of one’s own hand which acts as if it had a will of its own. The symptoms may differ depending on whether the brain lesion is anterior, posterior, callosal or subcortical, but the relative classifications are not conclusive. This study investigates the role of white matter disconnections in a patient whose symptoms are inconsistent with the mapping of the lesion site. A repeated neuropsychological investigation was associated with a review of the literature on the topic to identify the frequency of various different symptoms relating to this syndrome. Furthermore, an analysis of the neuroimaging regarding structural connectivity allowed us to investigate the grey matter lesions and white matter disconnections. The results indicated that some of the patient’s symptoms were associated with structures that, although not directly damaged, were dysfunctional due to a disconnection in their networks. This suggests that the anarchic hand may be considered as a disconnection syndrome involving the integration of multiple antero-posterior, insular and interhemispheric networks. In order to comprehend this rare syndrome better, the clinical and neuroimaging data need to be integrated with the clinical reports available in the literature on the topic.

The Ecomedical Disconnection Syndrome

1999 ◽  
Vol 29 (1) ◽  
pp. 41 ◽  
Author(s):  
Peter J. Whitehouse
Keyword(s):  
Disconnection Syndrome

Is Alzheimer's disease a disconnection syndrome?

2007 ◽  
Vol 45 (14) ◽  
pp. 3315-3323 ◽  
Author(s):  
X. Delbeuck ◽  
F. Collette ◽  
M. Van der Linden
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Disconnection Syndrome
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