scholarly journals Antiallergic effect of an aqueous leaf extract of Pistia stratiotes in murine model of ovalbumin-induced allergic conjunctivitis

2014 ◽  
Vol 6 (4) ◽  
pp. 274 ◽  
Author(s):  
GeorgeAsumeng Koffuor ◽  
Samuel Kyei ◽  
EmmanuelA Asiamah ◽  
ClementNsobire Atobiga ◽  
Agnes Awuah ◽  
...  
Keyword(s):  
Murine Model ◽  
Allergic Conjunctivitis ◽  
Leaf Extract ◽  
Pistia Stratiotes ◽  
Antiallergic Effect ◽  
Aqueous Leaf Extract

scholarly journals Cytotoxic and Genotoxic Evaluation of the Aqueous and Hydroalcoholic Leaf and Bark Extracts of Crataegus oxyacantha in Murine Model

Plants ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2217
Author(s):  
Fany Renata Aguilera-Rodríguez ◽  
Ana Lourdes Zamora-Perez ◽  
Clara Luz Galván-Moreno ◽  
Rosalinda Gutiérrez-Hernández ◽  
Claudia Araceli Reyes Estrada ◽  
...  
Keyword(s):  
Murine Model ◽  
Leaf Extract ◽  
Micronucleus Test ◽  
Genotoxic Effects ◽  
Cytotoxic Effects ◽  
Blood Smears ◽  
Polychromatic Erythrocytes ◽  
Aqueous Leaf Extract ◽  
Peripheral Blood Smears ◽  
Sampling Times

Crataegus oxyacantha has been mainly used in traditional medicine for the treatment of cardiovascular diseases. However, its safety profile has not been fully established, since only the genotoxic effects of C. oxyacantha fruit have been described. Therefore, the objective of this work was evaluating the cytotoxicity and genotoxicity of the aqueous and hydroalcoholic leaf and bark extracts of C. oxyacantha by means of the micronucleus test in a murine model. Doses of 2000, 1000, and 500 mg/kg of both extracts were administered orally for 5 days in mice of the Balb-C strain. Peripheral blood smears were performed at 0, 24, 48, 72, and 96 h after each administration. The number of polychromatic erythrocytes (PCEs), micronucleated polychromatic erythrocytes (MNPCEs), and micronucleated erythrocytes (MNEs) was determined at the different sampling times. Our results showed that the leaf and bark of C. oxyacantha increase the number of MNEs at the 2000 mg/kg dose, and only the aqueous leaf extract decreases the number of PCEs at the same dose. Therefore, the aqueous and hydroalcoholic leaf and bark extracts of C. oxyacantha showed genotoxic effects, and only the aqueous leaf extract exhibited cytotoxic effects.

Protective influence of Carica papaya L. aqueous leaf extract against hyperuricemia and acute renal injury in a murine model

2016 ◽  
Author(s):  
Pacifico Eric Calderon ◽  
Chrizarah San Juan ◽  
Mary Grace San Pedro ◽  
Ariane Marie Reyes ◽  
Patrick Jerome Salom ◽  
...  
Keyword(s):  
Murine Model ◽  
Renal Injury ◽  
Leaf Extract ◽  
Carica Papaya ◽  
Acute Renal Injury ◽  
Aqueous Leaf Extract

scholarly journals Safety and antidiarrheal activity of Priva adhaerens aqueous leaf extract in a murine model

2014 ◽  
Vol 157 ◽  
pp. 251-256 ◽  
Author(s):  
Miriam Nansunga ◽  
Ambrose Barasa ◽  
Justus Abimana ◽  
Paul E. Alele ◽  
Josephine Kasolo
Keyword(s):  
Murine Model ◽  
Leaf Extract ◽  
Aqueous Leaf Extract ◽  
Antidiarrheal Activity

Cytoprotective and antiadhesive effects of aqueous leaf extract from Orthosiphon aristatus against uropathogenic E. coli

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381 ◽  
Author(s):  
S Sarshar ◽  
MR Asadi Karam ◽  
M Habibi ◽  
S Bouzari ◽  
X Qin ◽  
...  
Keyword(s):  
Leaf Extract ◽  
E Coli ◽  
Aqueous Leaf Extract

Insecticidal Activities of the Leaf Extract of the Invasive Alien Plant, Chromolaena odorata (L.) (Asteraceae) Against Macrotermes species (Termites)

2019 ◽  
Vol 35 (1) ◽  
pp. 145-153
Author(s):  
O. Uyi, ◽  
I.G. Amolo ◽  
A.D. Adetimehin
Keyword(s):  
Leaf Extract ◽  
Insect Pests ◽  
Chromolaena Odorata ◽  
Leaf Extracts ◽  
Alien Plant ◽  
Biological Efficacy ◽  
Invasive Alien Plant ◽  
Impregnation Technique ◽  
Aqueous Leaf Extract ◽  
Worker Caste

Several studies have demonstrated the biological efficacy of leaf, stem and root powders or extracts of Chromolaena odorata (L.) King and Robinson against insect pests but those that are focused on the biological efficacy of aqueous leaf extracts against Macrotermes species are scanty. Current management of termites with synthetic insecticides is being discouraged due to human and environmental hazards. Therefore, the insecticidal effectiveness of aqueous leaf extract C. odorata against Macrotermes species was investigated. Five concentrations (0, 2.5, 5.0, 7.5 and 10.0% (w/v)) of the aqueous extract of C. odorata plant were evaluated for repellency and toxicity on the worker caste of Macrotermes species following standard procedures. The filter paper impregnation technique was used for the bioassay. Percentage repellency was monitored for 30 minutes and mortality recorded at 12, 24 and 36 hours post exposure. The leaf extract of C. odorata significantly repelled 95% of Macrotermes species at the highest concentration of 10% (w/v) after 30 minutes post treatment exposure. Mortality of Macrotermes species was independent of treatment concentration, but dependent on duration of exposure. All treatment concentrations of aqueous leaf extract of C. odorata caused significant mortality against Macrotermes species ranging between 94% and 98% compared to the control; indicating very great potential for adoption and use in the management of Macrotermes species.

Green Synthesis of Silver Nanoparticles by Allamanda cathartica L. Leaf Extract and Evaluation for Antimicrobial Activity

2013 ◽  
Vol 6 (4) ◽  
pp. 2260-2268
Author(s):  
M. Linga Rao ◽  
Bhumi G ◽  
Savithramma N
Keyword(s):  
Antimicrobial Activity ◽  
Silver Nanoparticles ◽  
Leaf Extract ◽  
Fusarium Species ◽  
Inhibition Zone ◽  
Fungal Species ◽  
Green Technology ◽  
Metallic Silver ◽  
Synthesis Of Nanoparticles ◽  
Aqueous Leaf Extract

Silver nanoparticles (SNPs) exhibit tremendous applications in medicine as antimicrobial agent.  The use of different parts of plants for the synthesis of nanoparticles is considered as a green technology as it does not involve any harmful chemicals.  In the present study, we report a rapid biosynthesis of silver nanoparticles from aqueous leaf extract of medicinal plant Allamanda cathartica.  The active phytochemicals present in the plant were responsible for the quick reduction of silver ion to metallic silver nanoparticles. The reduced silver nanoparticles were characterized by using UV-Vis spectrophotometry, Scanning Electron Microscope (SEM), Energy Dispersive Analysis of X-ray (EDAX) and Atomic Force Microscopy (AFM).  The spherical shaped silver nanoparticles were observed and it was found to 19-40 nm range of size.  These phytosynthesized SNPs were tested for their antimicrobial activity and it analyzed by measuring the inhibitory zone. A. cathartica aqueous leaf extract of SNPs showed highest toxicity to Pseudomonas followed by Klebsiella, Bacillus and E. coli and lowest toxicity towards Proteus. In fungal species, highest inhibition zone was noted against Rhizopus followed by Curvularia, Aspergillus flavus and Aspergillus niger and minimum inhibition zone was observed against Fusarium species.  These results suggest a promising potential of Indian plant-based green chemistry for production of SNPs for biomedical and nanotechnology applications.

Synthesis and characterization of TiO2 NPs by aqueous leaf extract of Coleus aromaticus and assess their antibacterial, larvicidal, and anticancer potential

2021 ◽  
pp. 111335
Author(s):  
Mathiyazhagan Narayanan ◽  
Paramasivam Vigneshwari ◽  
Devarajan Natarajan ◽  
Sabariswaran Kandasamy ◽  
Mishal Alsehli ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Synthesis And Characterization ◽  
Tio2 Nps ◽  
Aqueous Leaf Extract ◽  
Coleus Aromaticus

scholarly journals Oral acute and sub-chronic toxicity assessment of aqueous leaf extract of Simarouba glauca DC (Paradise tree)

2021 ◽  
Vol 8 ◽  
pp. 239-247
Author(s):  
SD. E. Osagie-Eweka ◽  
N.E.J. Orhue ◽  
E.K.I. Omogbai ◽  
F.C. Amaechina
Keyword(s):  
Leaf Extract ◽  
Chronic Toxicity ◽  
Toxicity Assessment ◽  
Aqueous Leaf Extract ◽  
Simarouba Glauca
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