Association of serum copper level with fasting serum glucose in south Indian women with gestational diabetes mellitus

Abstract Objective The objective of this study was to assess the levels of serum myonectin and irisin in pregnant women with and without gestational diabetes mellitus (GDM). Method A total of 80 pregnant women participated in our study (which consisted of 40 patients with GDM, 40 participants as the control group). Myonectin and irisin levels were analyzed through the ELISA technique, in addition to metabolic parameters in the serum samples of the participants. Results It was found that the levels of irisin and myonectin were lower in the GDM group compared to the control group. Moreover, it was determined that the values of age (p<0.001), body mass index (p=0.001), gravida (p=0.001), parity (p = 0.016), fasting serum glucose (p=0.001), fasting serum insulin (p=0.007), postprandial serum glucose (p=0.006), HbA1c (p<0.001), HOMA-IR (p<0.001) were higher; HDL cholesterol (p<0.001) was lower. Insulin resistance was significantly higher in the GDM group. Conclusions Levels of myonectin and irisin were determined to be low in the GDM group. Our results have demonstrated that myonectin and irisin could play a role in the development of GDM and that irisin as well as myonectin could be a novel biomarker for GDM.

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Peri-conceptional diet patterns and risk of gestational diabetes mellitus in South Indian women

Proceedings of The Nutrition Society ◽

10.1017/s0029665121002974 ◽

2021 ◽

Vol 80 (OCE5) ◽

Author(s):

A. Mahendra ◽

S.H. Kehoe ◽

S.R. Crozier ◽

K. Kumaran ◽

G.V. Krishnaveni ◽

...

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Indian Women ◽

Diet Patterns ◽

South Indian

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Prevalence and associated risk factors of gestational diabetes mellitus

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20211559 ◽

2021 ◽

Vol 10 (5) ◽

pp. 2135

Author(s):

Irkm Sivasarupa ◽

Sivankumar Kumarapillai

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

South Asian ◽

Significant Risk ◽

Cross Sectional ◽

Indian Women ◽

South Indian ◽

Associated Risk Factors

Gracelyn et al conducted a cross-sectional hospital-based study regarding the prevalence and significant risk factors of gestational diabetes mellitus in South Indian women.1 This study is important at this time because of the high frequency of gestational diabetes in South Asian ethnic groups especially in South Indian women.

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Serum Glucose-Dependent Insulinotropic Polypeptide in Gestational Diabetes Mellitus

Metabolism ◽

10.1016/j.metabol.2020.154644 ◽

2021 ◽

Vol 116 ◽

pp. 154644

Author(s):

Oleksandr Zhelezniakov ◽

Natalia Zhelezniakova

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Serum Glucose

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Clinical profile, outcomes, and progression to type 2 diabetes among Indian women with gestational diabetes mellitus seen at a diabetes center in south India

Indian Journal of Endocrinology and Metabolism ◽

10.4103/2230-8210.131205 ◽

2014 ◽

Vol 18 (3) ◽

pp. 400 ◽

Cited By ~ 17

Author(s):

Mohan Viswanathan ◽

Harish Ranjani ◽

Balaji Bhavadharini ◽

RanjitMohan Anjana ◽

ManniMohanraj Mahalakshmi ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

South India ◽

Clinical Profile ◽

Indian Women ◽

Diabetes Center

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Prevalence of pregnancy induced thyroid disorders, diabetes and hypertension in a tertiary care teaching hospital: an observational study

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20193535 ◽

2019 ◽

Vol 8 (8) ◽

pp. 3201

Author(s):

Gowthami Mummalaneni ◽

Tamaraba Narasingarao ◽

Krishna Kumari Myneni

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Gestational Hypertension ◽

Tertiary Care ◽

Thyroid Disorders ◽

Gestational Period ◽

South Indian ◽

Wide Range ◽

Study Population

Background: Pregnancy induced thyroid disorders, gestational diabetes mellitus (GDM) and gestational hypertension are common problems in women with gestational period. Published literate shows wide range of prevalence in pregnancy induced disorders in other states of India, and as of now the exact prevalence in our study population is not studied. Hence, there present study was aimed to know the prevalence of pregnancy induced disorders in pregnant women in South Indian population.Methods: A total of 120 subjects were followed-up at the time of recruitment to entire gestational period. Standard guidelines were followed for the assessment of thyroid hormone levels, glucose tolerance test (OGTT) and blood pressure values at different intervals and positions. Apart from detailed clinical history has been taken and routine basic and obstetrical investigations were done.Results: Prevalence of thyroid dysfunction (15.0%), gestational diabetes mellitus (11.7%) and gestational hypertension (9.2%) was reported in the present study population. Subclinical hypothyroidism was highest prevalence amount thyroid disorders. Gestational diabetes subjects have mean blood glucose levels of 230.68±17.48 mg/dL with OGTT test. Gestational hypertensive patients had SBP of 152.4±10.8 and DBP of 96.6±6.4; pre-hypertensive subjects had SBP of 134.2±5.48 and DBP of 6.8±4.6 respectively.Conclusions: Our study findings were slightly higher than normal prevalence’s which are reported earlier by various authors. We suggested that early screening, diagnosis and treatment are warranted for the prevention of maternal and fetal complications in Indian population.

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