Serous tubal intraepithelial carcinoma: Emerging trend in ovarian neoplasm: A must know for a pathologist

2021 ◽  
Vol 10 (5) ◽  
pp. 225
Author(s):  
Banyameen Iqbal
Keyword(s):  
Ovarian Neoplasm ◽  
Serous Tubal Intraepithelial Carcinoma ◽  
Intraepithelial Carcinoma

scholarly journals Serous tubal intraepithelial carcinoma lesions are common in primary peritoneal serous carcinomas

2016 ◽  
Vol 141 ◽  
pp. 144-145
Author(s):  
M. Zakhour ◽  
A. Laury ◽  
J. Lester ◽  
B.J. Rimel ◽  
C. Walsh ◽  
...  
Keyword(s):  
Serous Tubal Intraepithelial Carcinoma ◽  
Intraepithelial Carcinoma

scholarly journals Serous Tubal Intraepithelial Carcinoma or Not? Metastases to Fallopian Tube Mucosa Can Masquerade as In Situ Lesions

2017 ◽  
Vol 141 (10) ◽  
pp. 1313-1315 ◽  
Author(s):  
Reena Singh ◽  
Kathleen R. Cho
Keyword(s):  
Fallopian Tube ◽  
De Novo ◽  
Data Sources ◽  
High Grade ◽  
Serous Tubal Intraepithelial Carcinoma ◽  
Different Types ◽  
Intraepithelial Carcinoma ◽  
A Site ◽  
Immunohistochemical Stains

Context.— Nonuterine high-grade serous carcinomas (HGSCs) are believed to arise most often from precursors in the fallopian tube referred to as serous tubal intraepithelial carcinomas (STICs). A designation of tubal origin has been suggested for all cases of nonuterine HGSC if a STIC is identified. Objective.— To highlight that many different types of nongynecologic and gynecologic carcinomas, including HGSC, can metastasize to the tubal mucosa and mimic de novo STIC. Data Sources.— A mini-review of several recently published studies that collectively examine STIC-like lesions of the fallopian tube. Conclusions.— The fallopian tube mucosa can be a site of metastasis from carcinomas arising elsewhere, and pathologists should exercise caution in diagnosing STIC without first considering the possibility of metastasis. Routinely used immunohistochemical stains can often be used to determine if a STIC-like lesion is tubal or nongynecologic in origin. In the context of uterine and nonuterine HGSC, STIC may represent a metastasis rather than the site of origin, particularly when widespread disease is present.

scholarly journals Stathmin 1 and p16INK4A are sensitive adjunct biomarkers for serous tubal intraepithelial carcinoma

2015 ◽  
Vol 139 (1) ◽  
pp. 104-111 ◽  
Author(s):  
Marián Novak ◽  
Jenny Lester ◽  
Alison M. Karst ◽  
Vinita Parkash ◽  
Michelle S. Hirsch ◽  
...  
Keyword(s):  
Serous Tubal Intraepithelial Carcinoma ◽  
Stathmin 1 ◽  
Intraepithelial Carcinoma
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