scholarly journals Acute kidney injury network criteria as a prognostic factor in cirrhotic patients with spontaneous bacterial peritonitis

2018 ◽  
Vol 30 (4) ◽  
pp. 264
Author(s):  
Hazem Hakim El-Beltagy El-Menshawy ◽  
Salah El-Gamal ◽  
NeveenF Abbas ◽  
Omar El-Metwally
Keyword(s):  
Acute Kidney Injury ◽  
Prognostic Factor ◽  
Spontaneous Bacterial Peritonitis ◽  
Kidney Injury ◽  
Acute Kidney Injury Network ◽  
Bacterial Peritonitis ◽  
Cirrhotic Patients

scholarly journals Predictors of Development of Hepatorenal Syndrome in Hospitalized Cirrhotic Patients with Acute Kidney Injury

2021 ◽  
Vol 10 (23) ◽  
pp. 5621
Author(s):  
Roula Sasso ◽  
Ahmad Abou Yassine ◽  
Liliane Deeb
Keyword(s):  
Acute Kidney Injury ◽  
Spontaneous Bacterial Peritonitis ◽  
Hepatorenal Syndrome ◽  
Kidney Injury ◽  
Alcoholic Cirrhosis ◽  
Clinical Feature ◽  
Decompensated Liver Cirrhosis ◽  
Bacterial Peritonitis ◽  
Cirrhotic Patients ◽  
End Stage

Hepatorenal syndrome (HRS) is a type of acute kidney injury (AKI), occurring in patients with decompensated liver cirrhosis and is associated with high mortality. We aim to describe the predictors associated with the development of HRS in cirrhotic patients with AKI. We retrospectively analyzed 529 cirrhotic patient encounters with AKI across all Northwell Health institutions between 1 January 2015 and 31 December 2018. We performed multivariate analyses to determine independent predictors of development of HRS. Alcoholic cirrhosis was the most common identified etiology of cirrhosis. The mean Model for End-Stage Liver Disease Scorewas18 (±7). Ascites was the most commonly identified clinical feature of portal hypertension. Infection was identified in 38.4% of patients with urinary tract infection/pyelonephritis being the most common. Spontaneous bacterial peritonitis occurred in 5.9% of patients. The most common cause of AKI was pre-renal. Hepatorenal syndrome was identified in 9.8% of patient encounters. Predictors of HRS were history of ascites, serum creatinine >2.5 mg/dL, albumin <3 g/dL, bilirubin >2 mg/dL and spontaneous bacterial peritonitis. We demonstrate strong predictors for the development of HRS which can aid clinicians to attain an early diagnosis of HRS, leading to prompt and targeted management and improving outcomes.

Acute Kidney Injury Network Criteria as a Predictor of Hospital Mortality in Cirrhotic Patients With Ascites

2012 ◽  
Vol 46 (3) ◽  
pp. e21-e26 ◽  
Author(s):  
Juliana Ribeiro de Carvalho ◽  
Cristiane Alves Villela-Nogueira ◽  
Ronir Raggio Luiz ◽  
Paula Lustosa Guzzo ◽  
Juliana Maria da Silva Rosa ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Hospital Mortality ◽  
Kidney Injury ◽  
Acute Kidney Injury Network ◽  
Cirrhotic Patients

Trends in Hospitalization, Acute Kidney Injury, and Mortality in Patients With Spontaneous Bacterial Peritonitis

2019 ◽  
Vol 53 (2) ◽  
pp. e68-e74 ◽  
Author(s):  
Kalpit Devani ◽  
Paris Charilaou ◽  
Palashkumar Jaiswal ◽  
Nirav Patil ◽  
Dhruvil Radadiya ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Spontaneous Bacterial Peritonitis ◽  
Kidney Injury ◽  
Bacterial Peritonitis

Urinary neutrophil gelatinase-associated lipocalin for diagnosis of spontaneous bacterial peritonitis

2019 ◽  
Vol 49 (3) ◽  
pp. 189-192 ◽  
Author(s):  
Tamer R Fouad ◽  
Eman Abdelsameea ◽  
Maha Elsabaawy ◽  
M. Ashraf Eljaky ◽  
Soha Zaki El-shenawy ◽  
...  
Keyword(s):  
Spontaneous Bacterial Peritonitis ◽  
Univariate Analysis ◽  
Kidney Injury ◽  
Meld Score ◽  
Urinary Ngal ◽  
Hepatitis C Infection ◽  
Bacterial Peritonitis ◽  
Neutrophil Gelatinase Associated Lipocalin ◽  
Cirrhotic Patients ◽  
Neutrophil Gelatinase

Cirrhotic patients with ascites are at high risk of developing spontaneous bacterial peritonitis (SBP). After exclusion of patients with acute kidney injury (AKI) or other infections, urinary neutrophil gelatinase-associated lipocalin (NGAL) levels were compared between two matched groups of Egyptian cirrhotic patients with ascites, mostly secondary to hepatitis C infection (98%). Group 1 had SBP (n = 41) and group 2 did not (n = 45). By univariate analysis, urinary-NGAL, high total bilirubin, serum creatinine, international normalised ratio and the Model of End-Stage Liver Disease (MELD) score and low platelet count were all significantly correlated with the presence of SBP, but only urinary-NGAL could independently predict development of SBP ( P = 0.001). Urinary-NGAL at a cut-off value of 1225 pg/mL, showed a sensitivity of 95% and a specificity of 76%, and is therefore a most useful tool.

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