scholarly journals Assessment of c-reactive protein level in oral submucous fibrosis and oral squamous cell carcinoma patient

2021 ◽  
Vol 13 (5) ◽  
pp. 748
Author(s):  
Geeta Sharma ◽  
Randhir Kumar ◽  
SharibAbdus Salam ◽  
Prashant Bhasin ◽  
NishantKumar Tewari ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Protein Level ◽  
Oral Submucous Fibrosis ◽  
C Reactive Protein ◽  
Squamous Cell Carcinoma Patient ◽  
Reactive Protein ◽  
Submucous Fibrosis

scholarly journals Association between the C-reactive protein/albumin ratio and prognosis in patients with oral squamous cell carcinoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kenji Yamagata ◽  
Satoshi Fukuzawa ◽  
Naomi Ishibashi-Kanno ◽  
Fumihiko Uchida ◽  
Hiroki Bukawa
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Prognostic Marker ◽  
Squamous Cell ◽  
Inflammatory Markers ◽  
Outcome Variable ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Significant Difference

AbstractThe systemic inflammatory response is known to be associated with poor outcomes in patients with various types of cancer. The C-reactive protein (CRP)/albumin (Alb) ratio (CAR) has been reported as a novel inflammation-based prognostic marker. We have evaluated the prognostic value of inflammatory markers for patients with oral squamous cell carcinoma (OSCC). The study population included 205 patients treated with OSCC between 2013 and 2018. The primary predictor variable was the inflammatory markers. The primary outcome variable was overall survival (OS). Univariate and multivariate analyses were performed using a Cox proportional hazards model to identify independent prognostic factors. The CAR had the highest area under the curve (AUC) values compared with other markers in the receiver operating characteristic (ROC) curve analysis. The cutoff value for CAR was 0.032 (AUC 0.693, P < 0.001). There was a significant difference in OS when patients were stratified according to CAR, with 79.1% for CAR < 0.032 and 35% for CAR ≥ 0.032 (P < 0.001). Cox multivariate analysis identified independent predictive factors for OS: age (hazard ratio [HR] 2.155, 95% confidence interval [CI] 1.262–3.682; P = 0.005), stage (HR 3.031, 95% CI 1.576–5.827; P = 0.001), and CAR (HR 2.859, 95% CI 1.667–4.904; P < 0.001). CAR (≥ 0.032 vs. < 0.032) is a good prognostic marker in patients with OSCC in terms of age and stage.

Oral squamous cell carcinoma in the background of oral submucous fibrosis is a distinct clinicopathological entity with better prognosis

2017 ◽  
Vol 46 (6) ◽  
pp. 448-453 ◽  
Author(s):  
Amol Ramchandra Gadbail ◽  
Minal Chaudhary ◽  
Madhuri Gawande ◽  
Alka Hande ◽  
Sachin Sarode ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis

scholarly journals The prevalence of oral squamous cell carcinoma with oral submucous fibrosis

2020 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Mohd Saalim ◽  
Kaustubh Sansare ◽  
FrenyR Karjodkar ◽  
Satyapal Johaley ◽  
IbrahimK Ali ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis
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