Trimester-specific reference ranges for thyroid function tests in South Indian women

2019 ◽  
Vol 16 (1) ◽  
pp. 51
Author(s):  
MahmoodDhahir Al-Mendalawi
Keyword(s):  
Thyroid Function ◽  
Specific Reference ◽  
Reference Ranges ◽  
Thyroid Function Tests ◽  
Indian Women ◽  
Function Tests ◽  
South Indian

Trimester-specific reference ranges for thyroid function tests in South Indian women

2018 ◽  
Vol 15 (3) ◽  
pp. 117
Author(s):  
Vijaya Sarathi ◽  
KSandhya Rani ◽  
Sunanda Tirupati ◽  
KDileep Kumar
Keyword(s):  
Thyroid Function ◽  
Specific Reference ◽  
Reference Ranges ◽  
Thyroid Function Tests ◽  
Indian Women ◽  
Function Tests ◽  
South Indian

scholarly journals Changes of Thyroid Function Tests in Pregnancy and Contribution of Trimester Specific Reference Ranges to Diagnosis

2015 ◽  
Vol 35 (1) ◽  
pp. 43-48
Author(s):  
Özlem ÇAKIR MADENCİ ◽  
Nihal YÜCEL ◽  
Lale KÖROĞLU DAĞDELEN ◽  
Gülşen MUTLUOĞLU ◽  
Hasan Emin KAYA ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Specific Reference ◽  
Reference Ranges ◽  
Thyroid Function Tests ◽  
Function Tests ◽  
In Pregnancy

scholarly journals Trimester-Specific Reference Ranges for Thyroid Hormones in Iranian Pregnant Women

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Ladan Mehran ◽  
Atieh Amouzegar ◽  
Hossein Delshad ◽  
Sahar Askari ◽  
Mehdi Hedayati ◽  
...  
Keyword(s):  
Thyroid Hormones ◽  
Pregnant Women ◽  
Thyroid Function ◽  
Final Analysis ◽  
Reference Intervals ◽  
Specific Reference ◽  
Reference Ranges ◽  
Thyroid Function Tests ◽  
Thyroid Disorder ◽  
Function Tests

Background. Due to many physiological changes during pregnancy, interpretation of thyroid function tests needs trimester-specific reference intervals for a specific population. There is no normative data documented for thyroid hormones on healthy pregnant women in Iran. The present survey was conducted to determine trimester-specific reference ranges for serum TSH, thyroxine (TT4), and triiodothyronine (TT3).Methods. The serum of 215 cases was analyzed for measurement of thyroid function tests by immunoassay method of which 152 iodine-sufficient pregnant women without thyroid autoantibodies and history of thyroid disorder or goiter were selected for final analysis. Reference intervals were defined as 5th and 95th percentiles.Results. Reference intervals in the first, second, and third trimesters were as follows: TSH (0.2–3.9, 0.5–4.1, and 0.6–4.1 mIU/l), TT4 (8.2–18.5, 10.1–20.6, and 9–19.4 μg/dl), and TT3 (137.8–278.3, 154.8–327.6, and 137–323.6 ng/dl), respectively. No correlation was found between TSH and TT4 or TT3. Significant correlation was found between TT4 and TT3 in all trimesters (r=0.35,P<0.001).Conclusion. The reference intervals of thyroid function tests in pregnant women differ among trimesters. Applying trimester-specific reference ranges of thyroid hormones is warranted in order to avoid misclassification of thyroid dysfunction during pregnancy.

Young adult reference ranges for thyroid function tests on the Centaur immunoassay analyser

2006 ◽  
Vol 63 (4) ◽  
pp. 163-165 ◽  
Author(s):  
M. Alqahatani ◽  
W. Tamimi ◽  
M Aldaker ◽  
F. Alenzi ◽  
H. Tamim ◽  
...  
Keyword(s):  
Young Adult ◽  
Thyroid Function ◽  
Reference Ranges ◽  
Thyroid Function Tests ◽  
Function Tests

Gestation specific reference intervals for thyroid function tests in pregnancy

2016 ◽  
Vol 54 (8) ◽  
Author(s):  
Süleyman Akarsu ◽  
Filiz Akbiyik ◽  
Eda Karaismailoglu ◽  
Zeliha Gunnur Dikmen
Keyword(s):  
Pregnant Women ◽  
Thyroid Function ◽  
First Trimester ◽  
Reference Intervals ◽  
Specific Reference ◽  
Thyroid Function Tests ◽  
Second Trimester ◽  
Third Trimester ◽  
The Third ◽  
Function Tests

AbstractThyroid function tests are frequently assessed during pregnancy to evaluate thyroid dysfunction or to monitor pre-existing thyroid disease. However, using non-pregnant reference intervals can lead to misclassification. International guidelines recommended that institutions should calculate their own pregnancy-specific reference intervals for free thyroxine (FT4), free triiodothyronine (FT3) and thyroid-stimulating hormone (TSH). The objective of this study is to establish gestation-specific reference intervals (GRIs) for thyroid function tests in pregnant Turkish women and to compare these with the age-matched non-pregnant women.Serum samples were collected from 220 non-pregnant women (age: 18–48), and 2460 pregnant women (age: 18–45) with 945 (39%) in the first trimester, 1120 (45%) in the second trimester, and 395 (16%) in the third trimester. TSH, FT4 and FT3 were measured using the Abbott Architect i2000SR analyzer.GRIs of TSH, FT4 and FT3 for first trimester pregnancies were 0.49–2.33 mIU/L, 10.30–18.11 pmol/L and 3.80–5.81 pmol/L, respectively. GRIs for second trimester pregnancies were 0.51–3.44 mIU/L, 10.30–18.15 pmol/L and 3.69–5.90 pmol/L. GRIs for third trimester pregnancies were 0.58–4.31 mIU/L, 10.30–17.89 pmol/L and 3.67–5.81 pmol/L. GRIs for TSH, FT4 and FT3 were different from non-pregnant normal reference intervals.TSH levels showed an increasing trend from the first trimester to the third trimester, whereas both FT4 and FT3 levels were uniform throughout gestation. GRIs may help in the diagnosis and appropriate management of thyroid dysfunction during pregnancy which will prevent both maternal and fetal complications.

Changes in Thyroid Function Across Adolescence: A Longitudinal Study

2020 ◽  
Vol 105 (4) ◽  
pp. e1162-e1170 ◽  
Author(s):  
Purdey J Campbell ◽  
Suzanne J Brown ◽  
Phillip Kendrew ◽  
Michelle Lewer ◽  
Ee Mun Lim ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Twin Study ◽  
Specific Reference ◽  
Sexually Dimorphic ◽  
Reference Ranges ◽  
Thyroid Function Tests ◽  
Longitudinal Analyses ◽  
Free Triiodothyronine ◽  
Longitudinal Twin Study ◽  
Abbott Architect

Abstract Objective There are no large, longitudinal studies of thyroid function across adolescence. The aims of this study were to examine longitudinal trends in thyrotropin (TSH), free triiodothyronine (fT3) and free thyroxine (fT4) and determine age-specific reference ranges. Methods Thyroid function was assessed in 3415 participants in the Brisbane Longitudinal Twin Study at ages 12, 14, and 16, using the Abbott ARCHITECT immunoassay. Longitudinal analyses were adjusted for body mass index and puberty. Results In girls, mean fT4 (± SE) increased between age 12 and 14 (by 0.30 ± 0.08 pmol/L; P &lt; 0.001), while remaining unchanged in boys; from age 14 to 16, fT4 increased in both girls (by 0.42 ± 0.07 pmol/L; P &lt; 0.001) and boys (0.64 ± 0.07 pmol/L, P &lt; 0.001). There was a slight increase in fT3 from age 12 to 14 years in girls (by 0.07 ± 0.03 pmol/L; P = 0.042), with a more marked increase in boys (0.29 ± 0.03 pmol/L; P &lt; 0.001), followed by a decrease from age 14 to 16 in both sexes (girls, by 0.53 ± 0.02 pmol/L; P &lt; 0.001; boys, by 0.62 ± 0.03 pmol/L; P &lt; 0.001). From age 12 to 14, TSH showed no significant change in girls or boys, then levels increased from age 14 to 16 in both sexes (in girls, by 4.9%, 95% CI: 2.4%-10.3%, P = 0.020; in boys, by 7.2%, 95% CI: 3.0%-11.6%, P = 0.001). Reference ranges differed substantially from adults, particularly for fT4 and fT3. Conclusions Thyroid function tests in adolescents display complex, sexually dimorphic patterns. Implementation of adolescence-specific reference ranges may be appropriate.

scholarly journals Reference Ranges for Thyroid Function Tests in Premature Infants Beyond the First Week of Life

2001 ◽  
Vol 21 (8) ◽  
pp. 531-536 ◽  
Author(s):  
Susan J Clark ◽  
Douglas D Deming ◽  
Janet R Emery ◽  
Linda M Adams ◽  
Esther I Carlton ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Premature Infants ◽  
Reference Ranges ◽  
Thyroid Function Tests ◽  
Function Tests

Reference ranges for newer thyroid function tests in premature infants

1995 ◽  
Vol 126 (1) ◽  
pp. 122-127 ◽  
Author(s):  
Linda M. Adams ◽  
Janet R. Emery ◽  
Susan J. Clark ◽  
Esther I. Carlton ◽  
Jerald C. Nelson
Keyword(s):  
Thyroid Function ◽  
Premature Infants ◽  
Reference Ranges ◽  
Thyroid Function Tests ◽  
Function Tests

Trimester-specific reference intervals of thyroid function tests in Turkish pregnants

2019 ◽  
Vol 36 (5) ◽  
pp. 413-416
Author(s):  
Oktay Bulur ◽  
Zeliha Atak ◽  
Derun Taner Ertugrul ◽  
Esin Beyan ◽  
Emre Gunakan ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Reference Intervals ◽  
Specific Reference ◽  
Thyroid Function Tests ◽  
Function Tests
Sign in / Sign up

Export Citation Format

Share Document