scholarly journals The outcomes of renal cell carcinoma in a single tertiary care facility in Saudi Arabia

2020 ◽  
Vol 12 (2) ◽  
pp. 163
Author(s):  
Lujain Alqurashi ◽  
Marwan Al-Hajeili ◽  
Ehab Alsayyed ◽  
Budoor Salman ◽  
Hibatallah Mashat ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Saudi Arabia ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Tertiary Care ◽  
Care Facility ◽  
Tertiary Care Facility

Radionecrosis after Treating Oral Cavity & Oropharyngeal SCC

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P43-P44
Author(s):  
Sundip H Patel ◽  
Mike Yao ◽  
Tara Brennan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care ◽  
Care Facility ◽  
Tertiary Care Facility ◽  
Pertinent Data ◽  
Associated Risk Factors ◽  
Oropharynx Squamous Cell Carcinoma

Objective 1) The primary goal of this study was to evaluate the incidence of radionecrosis among patients treated with radiation therapy for oral cavity & oropharynx squamous cell carcinoma at our institution. Many patients with oral cavity & oropharyngeal cancers receive radiation to preserve the tongue, knowing the risks of post-treatment radionecrosis. However, recent protocols have intensified chemo-radiotherapy in an effort to improve local control while possibly increasing risk. 2) Among those patients with radionecrosis, we also analyzed their cancer treatment regimen, associated risk factors, the severity of the radionecrosis and the resulting treatment they recieved. Methods We performed a retrospective review of all adult patients at our tertiary care facility with biopsy proven squamous cell carcinoma of the oral cavity & oropharynx from 1999 to 2007 who completed a full course of radiotherapy at our facility with at least 6 months follow-up. Medical charts were reviewed for the presence of radionecrosis as well as for other corresponding, pertinent data. Results After reviewing 241 patients, a total of 107 patients were included. 5 of 65 with oropharynx disease had radionecrosis, revealing an incidence of 7.7%. Among the oral cavity group there were 8 out of 42 patients with radionecrosis, revealing an incidence of 19%. The overall incidence among our treatment group was 12.1%. Conclusions Radiation-induced necrosis of the oral cavity & oropharynx is still a significant complication in the treatment of head and neck cancer and poses a higher risk in the oral cavity than the oropharynx.

scholarly journals Decadal Experience of Renal Cell Carcinoma from a Tertiary Care Teaching Institute in North India

2018 ◽  
Vol 9 (4) ◽  
pp. 558-564
Author(s):  
Singh Kawaljit ◽  
Sinha Rahul Janak ◽  
Gupta Ashok ◽  
Singh Vishwajeet
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Tertiary Care ◽  
North India ◽  
Care Teaching

scholarly journals Renal Cell Carcinoma Metastatic to the Sinonasal Cavity: A Review and Report of 8 Cases

2018 ◽  
Vol 97 (9) ◽  
pp. E6-E12 ◽  
Author(s):  
Pierre-Louis Bastier ◽  
Dorothée Dunion ◽  
Guillaume de Bonnecaze ◽  
Elie Serrano ◽  
Ludovic de Gabory
Keyword(s):  
Renal Cell Carcinoma ◽  
Overall Survival ◽  
Cell Carcinoma ◽  
Nasal Obstruction ◽  
Survival Data ◽  
Renal Cell ◽  
Tertiary Care ◽  
Local Treatment ◽  
Initial Presentation ◽  
Local Response

Renal cell carcinoma (RCC) metastatic in the sinonasal cavity is rare. In many cases, it represents the initial presentation of RCC. We conducted a retrospective chart review to report the clinical presentation, imaging, and treatment of RCC metastases in the sinonasal cavity at two tertiary care referral centers. Our population was made up of 8 patients—6 men and 2 women, aged 55 to 86 years (mean: 66.9; median: 63.5)—who had been diagnosed with cancer in the sinonasal cavity. The most common complaints were epistaxis, nasal obstruction, and diplopia. Cancers were located in the ethmoid sinus (n = 3), nasal cavity (n = 2), sphenoid sinus (n = 2), and maxillary sinus (n = 1). Local treatment involved resection and adjuvant radiotherapy in 4 patients, surgery alone in 2 patients, and radiotherapy alone in the other 2. The lesion was embolized before surgery in 4 cases. We also performed a critical review of similar published cases. Our literature review covered 53 cases of RCC metastatic to the sinonasal cavity, including ours. Metastases were the first presentation of RCC in 24 of these cases (45.3%); in our series, the metastases led to the diagnosis of the primary RCC in 3 cases (37.5%). In the 53 reported cases, metastatic resection was performed on 35 patients (66.0%). Survival data were available for 22 of these operated patients, and 17 of them achieved a complete local response. Adjunctive radiotherapy was not associated with a better local response. Overall survival was significantly better in patients who had an isolated metastasis rather than multiple metastases (p = 0.013). There was no difference in overall survival between patients whose metastasis represented the initial presentation of RCC and those whose metastasis did not (p = 0.95). We recommend that sinonasal metastasis be suspected in the event of unilateral nasal bleeding or nasal obstruction in patients diagnosed with RCC. Embolization may prevent abundant bleeding during removal. Surgery may improve the quality of life of these patients while decreasing nasal obstruction and bleeding.

scholarly journals A Prospective Study on the Incidence and Outcomes of Neonatal Thrombocytopenia at a Tertiary Care Facility in Central Saudi Arabia

2018 ◽  
Vol 18 (5) ◽  
pp. E3-E12
Author(s):  
Mohamed Eltawel ◽  
Talal AlHarbi ◽  
Khaled AlJamaan ◽  
Saif Alsaif ◽  
Yosra Ali ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Prospective Study ◽  
Tertiary Care ◽  
Care Facility ◽  
Tertiary Care Facility ◽  
Neonatal Thrombocytopenia ◽  
A Prospective Study

scholarly journals Renal cell carcinoma at the time of presentation: a 5-year radiological survey at a tertiary care cancer hospital

2020 ◽  
Vol 7 (5) ◽  
pp. 1657
Author(s):  
Muhammad Omer Altaf ◽  
Asma Riaz ◽  
Mehreen Shafqat ◽  
Hamd Zahra ◽  
Naila Iqbal ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Tertiary Care ◽  
Developed Countries ◽  
Nodal Metastasis ◽  
Male Predominance ◽  
Cancer Hospital ◽  
Stage 1 ◽  
Time Of Presentation

Background: Renal cell carcinoma (RCC) is associated with highest mortality rates of all the genitourinary tumors with increased incidence in the past few decades. It is heterogenous tumor with several histological types. Main diagnostic approach is radiological imaging followed by histopathology.Methods: It is a retrospective study conducted at a tertiary care cancer hospital in Pakistan. We reviewed the record of all the RCC patients in terms of age, gender, radiological manifestation of tumor size, polarity, laterality, stage including nodal status, metastasis and histological type.Results: Our study included 149 patients of RCC. Mean age of presentation was 57 years with a male predominance. The most common stage of presentation was stage 3 seen in 41% patients followed by stage 1 in 37% patients. nodal metastasis was observed in around 13% patients and distant metastasis in 8% patients. Also, majority of the patient had histological subtype of clear cell CA (63%) followed by papillary CA (33%).Conclusions: Epidemiological features of renal cell CA are observed over a period of 5 years representing our population. The current trends show variation from those observed in developed countries depicting the struggle of healthcare awareness in developing countries.

scholarly journals Histopathological Spectrum of Nephrectomies - A 10 Year Descriptive Study from a Tertiary Care Center in South India

2020 ◽  
Vol 7 (47) ◽  
pp. 2752-2756
Author(s):  
Bhavya P. Mohan ◽  
Jaylakshmy Payippat Leelamma ◽  
Letha Vilasiniamma ◽  
Suresh Bhat
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Care Center ◽  
Tertiary Care ◽  
Age Distribution ◽  
Age Groups ◽  
Renal Diseases ◽  
Malignant Tumours ◽  
Neoplastic Lesions

BACKGROUND Nephrectomy is the standard surgical treatment of neoplastic and non-neoplastic lesions in the kidney and provides more insight into the detailed histopathology of renal lesions. We wanted to identify the age groups, gender distribution and different histopathological types and subtypes of non-neoplastic and neoplastic lesions in nephrectomy specimens over a period of ten years. METHODS A retrospective analysis was done over a period of ten years (January 2006 to December 2015). All nephrectomy specimens received in the Department of Pathology, Government Medical College, Kottayam were recorded from histopathology registers and analysed with regard to age, gender and histopathological types. RESULTS A total of 532 lesions was encountered in our analysis. Males (61.8 %) were affected more than females (38.2 %). Lesions were more on the left side (50.8 %) than right side (49.2 %). Non-neoplastic lesions (53 %) outnumbered neoplastic lesions (47 %). Inflammatory and obstructive causes constituted the majority (43.8 %) in non-neoplastic lesions and renal cell carcinoma was the commonest neoplasm (71.2 %). CONCLUSIONS There is a wide age distribution of renal diseases in the present study. Inflammatory and obstructive conditions constituted the most common indication for nephrectomy, followed by malignant tumours. KEYWORDS Renal Cell Carcinoma, Nephrectomy, Pyelonephritis, Simple Renal Cyst, Wilms Tumour

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