Affinity Maturation of an Epidermal Growth Factor Receptor Targeting Human Monoclonal Antibody ER414 by CDR Mutation

Immune Network ◽

10.4110/in.2012.12.4.155 ◽

2012 ◽

Vol 12 (4) ◽

pp. 155 ◽

Author(s):

Ki-Hwan Chang ◽

Min-Soo Kim ◽

Gwang-Won Hong ◽

Mi-Sun Seo ◽

Yong-Nam Shin ◽

...

Keyword(s):

Monoclonal Antibody ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Human Monoclonal Antibody ◽

Growth Factor Receptor ◽

Affinity Maturation ◽

Receptor Targeting ◽

Epidermal Growth

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Combined Epidermal Growth Factor Receptor Targeting with the Tyrosine Kinase Inhibitor Gefitinib (ZD1839) and the Monoclonal Antibody Cetuximab (IMC-C225)

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-04-0870 ◽

2004 ◽

Vol 10 (19) ◽

pp. 6487-6501 ◽

Author(s):

Pablo Matar ◽

Federico Rojo ◽

Raúl Cassia ◽

Gema Moreno-Bueno ◽

Serena Di Cosimo ◽

...

Keyword(s):

Monoclonal Antibody ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Receptor Targeting ◽

Epidermal Growth

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A phase 1 study of MM-121 (a fully human monoclonal antibody targeting the epidermal growth factor receptor family member ErbB3) in combination with cetuximab and irinotecan in patients with advanced cancers.

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.3076 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. 3076-3076 ◽

Author(s):

James M. Cleary ◽

Autumn Jackson McRee ◽

Bert H. O'Neil ◽

Sunil Sharma ◽

Joseph Pearlberg ◽

...

Keyword(s):

Monoclonal Antibody ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase 1 ◽

Human Monoclonal Antibody ◽

Growth Factor Receptor ◽

Phase 1 Study ◽

Epidermal Growth ◽

Receptor Family

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Conversion of a murine monoclonal antibody A13 targeting epidermal growth factor receptor to a human monoclonal antibody by guided selection

Experimental & Molecular Medicine ◽

10.3858/emm.2012.44.1.005 ◽

2012 ◽

Vol 44 (1) ◽

pp. 52 ◽

Author(s):

Ki-Hwan Chang ◽

Min-Soo Kim ◽

Gwang-Won Hong ◽

Yong-Nam Shin ◽

Se-Ho Kim

Keyword(s):

Monoclonal Antibody ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Human Monoclonal Antibody ◽

Growth Factor Receptor ◽

Murine Monoclonal Antibody ◽

Epidermal Growth

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Novel human monoclonal antibody against epidermal growth factor receptor as an imaging probe for hepatocellular carcinoma

Nuclear Medicine Communications ◽

10.1097/mnm.0b013e3283531d68 ◽

2012 ◽

Vol 33 (7) ◽

pp. 719-725 ◽

Author(s):

Chizuru Sogawa ◽

Atsushi B. Tsuji ◽

Chisato Yoshida ◽

Masayuki Inubushi ◽

Takako Furukawa ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Monoclonal Antibody ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Human Monoclonal Antibody ◽

Growth Factor Receptor ◽

Imaging Probe ◽

Epidermal Growth

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IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody for treatment of head and neck cancer

Seminars in Oncology ◽

10.1053/sonc.2002.35644 ◽

2002 ◽

Vol 29 (5 Suppl 14) ◽

pp. 18-30 ◽

Author(s):

Roy S. Herbst ◽

Waun Ki Hong

Keyword(s):

Monoclonal Antibody ◽

Epidermal Growth Factor Receptor ◽

Head And Neck Cancer ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Head And Neck ◽

Neck Cancer ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Receptor Monoclonal Antibody

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Inability of anti-epidermal growth factor receptor monoclonal antibody to block “autocrine” growth stimulation in transforming growth factor-secreting melanoma cells.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)71296-2 ◽

1984 ◽

Vol 259 (19) ◽

pp. 11895-11900

Author(s):

J E Kudlow ◽

M J Khosravi ◽

M S Kobrin ◽

W W Mak

Keyword(s):

Monoclonal Antibody ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Transforming Growth Factor ◽

Growth Factor Receptor ◽

Growth Stimulation ◽

Autocrine Growth ◽

Epidermal Growth ◽

Receptor Monoclonal Antibody

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Cetuximab: an IgG1 monoclonal antibody for the treatment of epidermal growth factor receptor-expressing tumours

Expert Opinion on Pharmacotherapy ◽

10.1517/14656566.5.7.1621 ◽

2004 ◽

Vol 5 (7) ◽

pp. 1621-1633 ◽

Author(s):

Yves Humblet

Keyword(s):

Monoclonal Antibody ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Igg1 Monoclonal Antibody ◽

Epidermal Growth

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Development of EMab-51, a Sensitive and Specific Anti-Epidermal Growth Factor Receptor Monoclonal Antibody in Flow Cytometry, Western Blot, and Immunohistochemistry

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy ◽

10.1089/mab.2017.0028 ◽

2017 ◽

Vol 36 (5) ◽

pp. 214-219 ◽

Author(s):

Shunsuke Itai ◽

Mika K. Kaneko ◽

Yuki Fujii ◽

Shinji Yamada ◽

Takuro Nakamura ◽

...

Keyword(s):

Monoclonal Antibody ◽

Flow Cytometry ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Western Blot ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Receptor Monoclonal Antibody

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Phase 1 study of anti-epidermal growth factor receptor monoclonal antibody in patients with solid tumors

mAbs ◽

10.4161/mabs.3.1.14021 ◽

2011 ◽

Vol 3 (1) ◽

pp. 67-75 ◽

Author(s):

Chong Wang ◽

Xiaohui He ◽

Bo Zhou ◽

Jing Li ◽

Bohua Li ◽

...

Keyword(s):

Monoclonal Antibody ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Solid Tumors ◽

Phase 1 ◽

Growth Factor Receptor ◽

Phase 1 Study ◽

Epidermal Growth ◽

Receptor Monoclonal Antibody

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Intratumoral infusion of the monoclonal antibody, mAb 425, against the epidermal-growth-factor receptor in patients with advanced malignant glioma

Cancer Immunology Immunotherapy ◽

10.1007/s002620050368 ◽

1997 ◽

Vol 44 (3) ◽

pp. 157-164 ◽

Author(s):

P. Wersäll ◽

I. Ohlsson ◽

P. Biberfeld ◽

V. P. Collins ◽

S. von Krusenstjerna ◽

...

Keyword(s):

Monoclonal Antibody ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Malignant Glioma ◽

Growth Factor Receptor ◽

Epidermal Growth

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