scholarly journals Maternal Outcome of Pregnant Mothers with Hypertensive Disorder of Pregnancy at Hospitals in Wolaita Zone, Southern Ethiopia

2018 ◽  
Vol 04 (02) ◽  
Author(s):  
Mohammed Suleiman Obsa ◽  
Eskinder Wolka
Keyword(s):  
Maternal Outcome ◽  
Southern Ethiopia ◽  
Hypertensive Disorder ◽  
Hypertensive Disorder Of Pregnancy ◽  
Pregnant Mothers

scholarly journals Clinical Characteristics and Maternal Outcome of Obstetrics Patients Admitted to the Intensive Care Unit: Cross Sectional Observational Study

2021 ◽  
Vol 6 (2) ◽  
pp. 1-6
Author(s):  
Tulasi Reddy ◽  
K. Rekha Rani ◽  
M. Chandramathi
Keyword(s):  
Critical Care ◽  
Observational Study ◽  
Maternal Mortality ◽  
Maternal Outcome ◽  
Severe Illness ◽  
Hypertensive Disorder ◽  
Care Hospital ◽  
Age Group ◽  
Cross Sectional ◽  
Hypertensive Disorder Of Pregnancy

Background: According to UNICEF India, annually 44,000 women die due to preventable pregnancy related causes in India. Globally, this ratio is 830 maternal deaths daily according to a WHO newsletter from 2018. ICU / HDU facility provides simultaneous expert obstetrics care and critical medical care under one roof. The concept of ICU / HDU was introduced as a bridge between routine obstetric care and ICU / HDU in under to bypass and decrease the ICU / HDU burden. ICU / HDU care is required for women requiring more detailed observation, intervention including basic support for a single failing organ system, extended post-op care and those stepping down from higher levels of care. Awareness regarding ICU / HDU care and its benefits need to be improved. This study aims to study the maternal outcome of women admitted in tertiary care hospital, Karimnagar, Telangana. Methodology: This is cross sectional observational study was conducted in the department of obstetrics and gynaecology at Chalmeda Anand Rao Institute of Medical Sciences and hospital, Karimnagar, Telangana from June 2019 to March 2020 after obtaining clearance from the institutional scientific and ethical committees. In this study total 600 patients were recruited, out of these 150 patients not met the inclusion criteria & 450 women recruited for questionnaire based proforma, were selected for the study calculated by SPSS 20 software. They have been subjected to thorough history taking, general, obstetric examination and assessment of antenatal records & management & their outcome. Results: The mean age group is 25 yrs. Also found most admission in age group between 20 to 30 yr. Most of the cases were belong to low socioeconomic status (99.2%), Occupationally maximum were unskilled worker (98.3%) in present study, Most of the cases were have secondary level of education (91.6%). In this present study 180 were hypertensive disorder of pregnancy, followed by 128 were haemorrhage disorder of pregnancy, 108 were medical disorder of pregnancy & 34 were sepsis. Maternal mortality was 8.7% in this study. Conclusion: Commonest cause of mortality was hypertensive disorder of pregnancy & more than one diagnosis on admission were the other risk factors for ICU / HDU admission. A dedicated ICU / HDU will go a long way in reducing maternal mortality as the responses time from onset of acute severe illness to provision of high quality critical care will be substantially reduced. Keywords: ICU / HDU, Maternal Outcome, Mortality, Critical Care Unit.

Adverse Perinatal Outcomes Associated with Stage 1 Hypertension in Pregnancy: A Retrospective Cohort Study

2021 ◽  
Author(s):  
Elizabeth Norton ◽  
Frances Shofer ◽  
Hannah Schwartz ◽  
Lorraine Dugoff
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort ◽  
Perinatal Outcomes ◽  
Hypertensive Disorder ◽  
Hypertension In Pregnancy ◽  
Increased Risk ◽  
Hypertensive Disorder Of Pregnancy ◽  
Adverse Perinatal Outcomes ◽  
Stage 1 ◽  
In Pregnancy

Objective To determine if women who newly met criteria for stage 1 hypertension in early pregnancy were at increased risk for adverse perinatal outcomes compared with normotensive women. Study Design We conducted a retrospective cohort study of women who had prenatal care at a single institution and subsequently delivered a live infant between December 2017 and August 2019. Women with a singleton gestation who had at least two prenatal visits prior to 20 weeks of gestation were included. We excluded women with known chronic hypertension or other major maternal illness. Two groups were identified: (1) women newly diagnosed with stage 1 hypertension before 20 weeks of gestation (blood pressure [BP] 130–139/80–89 on at least two occasions) and (2) women with no known history of hypertension and normal BP (<130/80 mm Hg) before 20 weeks of gestation. The primary outcome was any hypertensive disorder of pregnancy; secondary outcomes were indicated preterm birth and small for gestational age. Generalized linear models were used to compare risk of adverse outcomes between the groups. Results Of the 1,630 women included in the analysis, 1,443 women were normotensive prior to 20 weeks of gestation and 187 women (11.5%) identified with stage 1 hypertension. Women with stage 1 hypertension were at significantly increased risk for any hypertensive disorder of pregnancy (adjusted risk ratio [aRR]: 1.86, 95% confidence interval [CI]: 1.12–3.04) and indicated preterm birth (aRR: 1.83, 95% CI: 1.12–3.02). Black women and obese women with stage 1 hypertension were at increased for hypertensive disorder of pregnancy compared with white women and nonobese women, respectively (aRR: 1.32, 95% CI: 1.11–1.57; aRR: 1.69, 95% CI: 1.39–2.06). Conclusion These results provide insight about the prevalence of stage 1 hypertension and inform future guidelines for diagnosis and management of hypertension in pregnancy. Future research is needed to assess potential interventions to mitigate risk. Key Points

scholarly journals Hypertension, pregnancy and weather: is seasonality involved?

2014 ◽  
Vol 60 (2) ◽  
pp. 105-110 ◽  
Author(s):  
Brena Melo ◽  
Melania Amorim ◽  
Leila Katz ◽  
Isabela Coutinho ◽  
José Natal Figueiroa
Keyword(s):  
Relative Humidity ◽  
Correlation Coefficient ◽  
Pearson Correlation ◽  
Hypertensive Disorder ◽  
Air Humidity ◽  
Hypertensive Disorders Of Pregnancy ◽  
Monthly Temperature ◽  
Hypertensive Disorders ◽  
Relative Air Humidity ◽  
Hypertensive Disorder Of Pregnancy

Objective: The present study aimed at assessing the association between environmental temperature and the relative humidity of the air with frequency of hypertensive disorders of pregnancy. Methods: A prospective and retrospective, descriptive, ecological study was held at a teaching maternity in Recife, Brazil. Data from all 26.125 pregnant women admitted between 2000 and 2006 were analysed and 5.051 had the diagnosis of hypertensive disorder of pregnancy. The incidence percentages were calculated monthly per deliveries. Data on mean monthly temperature and relative humidity of the air were collected and monthly comparisons were conducted. February was chosen as the reference month due to its lowest incidence of the disease. The relative chance of hypertensive disorders of pregnancy for each other month was estimated by odds ratio and Pearson's correlation coefficient was used to calculate the relation between the incidence of hypertensive disorders of pregnancy and the mean monthly temperature and relative air humidity. Results: February presented the lowest mean monthly incidence (9.95%) and August the highest (21.54%). Pearson correlation coefficient revealed a higher incidence of hypertensive disorders of pregnancy in the cooler months (r= -0.26; p=0.046) and no significant effect of relative air humidity (r=0.20; p=0.128). Conclusion: The incidence of hypertensive disorders of pregnancy may be affected by variations in temperature, increasing during cooler periods.

scholarly journals From animal models to patients: the role of placental microRNAs, miR-210, miR-126, and miR-148a/152 in preeclampsia

2020 ◽  
Vol 134 (8) ◽  
pp. 1001-1025 ◽  
Author(s):  
Sonya Frazier ◽  
Martin W. McBride ◽  
Helen Mulvana ◽  
Delyth Graham
Keyword(s):  
Animal Models ◽  
Cell Types ◽  
Rodent Model ◽  
Hypertensive Disorder ◽  
Model Studies ◽  
Genetic Components ◽  
Immune Mediated ◽  
Hypertensive Disorder Of Pregnancy

Abstract Placental microRNAs (miRNAs) regulate the placental transcriptome and play a pathological role in preeclampsia (PE), a hypertensive disorder of pregnancy. Three PE rodent model studies explored the role of placental miRNAs, miR-210, miR-126, and miR-148/152 respectively, by examining expression of the miRNAs, their inducers, and potential gene targets. This review evaluates the role of miR-210, miR-126, and miR-148/152 in PE by comparing findings from the three rodent model studies with in vitro studies, other animal models, and preeclamptic patients to provide comprehensive insight into genetic components and pathological processes in the placenta contributing to PE. The majority of studies demonstrate miR-210 is upregulated in PE in part driven by HIF-1α and NF-κBp50, stimulated by hypoxia and/or immune-mediated processes. Elevated miR-210 may contribute to PE via inhibiting anti-inflammatory Th2-cytokines. Studies report an up- and downregulation of miR-126, arguably reflecting differences in expression between cell types and its multifunctional capacity. MiR-126 may play a pro-angiogenic role by mediating the PI3K-Akt pathway. Most studies report miR-148/152 family members are upregulated in PE. Evidence suggests they may inhibit DNA methylation of genes involved in metabolic and inflammatory pathways. Given the genetic heterogeneity of PE, it is unlikely that a single placental miRNA is a suitable therapeutic target for all patients. Investigating miRNAs in PE subtypes in patients and animal models may represent a more appropriate approach going forward. Developing methods for targeting placental miRNAs and specific placental cell types remains crucial for research seeking to target placental miRNAs as a novel treatment for PE.

scholarly journals Analysis of the effectiveness of aspirin for the prevention of preeclampsia and alternative methods of prevention

2021 ◽  
Vol 20 (1) ◽  
pp. 70-75
Author(s):  
E. V. Kudryavceva ◽  
V. V. Kovalev ◽  
N. N. Bayazitova ◽  
N. M. Milyaeva ◽  
A. V. Kaumova
Keyword(s):  
Literature Review ◽  
Scientific Literature ◽  
Alternative Methods ◽  
Relative Reduction ◽  
Preventive Strategy ◽  
Hypertensive Disorder ◽  
Scientific Review ◽  
Continue Research ◽  
Potential Alternative ◽  
Hypertensive Disorder Of Pregnancy

Introduction. Preeclampsia is a hypertensive disorder of pregnancy that remains one of e leading causes of maternal and perinatal morbidity and mortality. The preventive strategy of prophylaxis with acetylsalicylic acid gives only a relative reduction in risk, and in a significant part of cases is ineffective. At the same time, the issue of preeclampsia prophylaxis is extremely relevant, since there are no effective methods for treating this condition, with the exception of the completion of gestation.Purpose of the study. Based on the scientific literature, to evaluate the effectiveness of aspirin in the prevention of preeclampsia and to determine the possible reasons for the lack of effectiveness of such prevention.Materials and methods. We conducted a search for scientific literature, as a result of which 39 sources were selected for the final scientific review (2010-2020). The PubMed, ResearchGate and Elibrary databases were used to search for scientific literature.Results and discussion. The article presents a literature review of the analysis of the effectiveness of aspirin for the prevention of preeclampsia over the past 5 years, describes the mechanism of action of aspirin, presents studies that confirm or refute the effectiveness of aspirin depending on the dosage and gestational age. Potential alternative agents for the prevention of preeclampsia in cases of aspirin ineffectiveness have been reviewed.Conclusion. Literature review data show that the effectiveness of aspirin for the prevention of preeclampsia depends on the chronobiological effect, compliance, gestational duration and dosage. It is necessary to continue research on the effectiveness of aspirin, and studies carried out on the Russian population will be of particular value for the Russian Federation.

scholarly journals Fear of Childbirth and Associated Factors Among Pregnant Mothers Who Attend Antenatal Care Service at Jinka Public Health Facilities, Jinka Town, Southern Ethiopia

2021 ◽  
pp. IJCBIRTH-D-20-00029
Author(s):  
Aynalem Yetwale ◽  
Eneyew Melkamu
Keyword(s):  
Antenatal Care ◽  
Health Center ◽  
Previous History ◽  
Southern Ethiopia ◽  
Systematic Sampling ◽  
Fear Of Childbirth ◽  
Childbirth Fear ◽  
Two Samples ◽  
History Of ◽  
Pregnant Mothers

BACKGROUNDWomen face many challenges from conception to postpartum, and fear of childbirth is one of the challenges the women encounter during pregnancy. This could have resulted from different perspectives and it could in turn lead to various pregnancy and childbirth problems. Thus, understanding childbirth fear and factors associated with this is of paramount importance and this study was aimed at addressing this issue.METHODOLOGYA facility-based cross-sectional study was done on 423 pregnant mothers who came for antenatal care services at Jinka hospital and Jinka health center. The study was conducted from June 1to 30, 2018. The sample size was calculated using the single population proportion formula and samples were taken after proportional allocation was done for the hospital and health center using the proportion allocation formula. Individual participants were selected with a systematic sampling technique using k-value of 2 for both the hospital and health center and the first participant was selected by the lottery method from the first two samples. Data were entered into epi-data version 3.1.1. and exported into statistical packages for social sciences version 21.0 for cleaning and further analysis. The level of significance was declared at a p value of less than 0.05 in multivariable logistic regression model. Narratives, figures, and tables were used to put the result.RESULTFrom 423 samples, two of the questionnaires were incomplete and thus 421 were used for analysis giving a response rate of 99.5%. Around a quarter of 102 (24.2%) mothers had fear of childbirth and the remaining 319 (75.8%) had no fear of childbirth. From the factors under consideration, history of previous pregnancy complications, previous history of labor and delivery complications, educational status, and depression status were significantly associated with a mother’s fear of childbirth.CONCLUSIONEven though it is physiological to have some fear of childbirth, the figure obtained is relatively higher. Factors found to have a significant effect on childbirth fear are those which could be tackled through improved health literacy and integrated maternal health services.

scholarly journals PERINATAL OUTCOME IN BABIES IN RELATION TO SEVERITY OF MATERNAL HYPERTENSION

2020 ◽  
Vol 4 (12) ◽  
Author(s):  
Jewel Maria George ◽  
Thomas Antony
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Perinatal Outcome ◽  
Neonatal Resuscitation ◽  
Categorical Variables ◽  
Hypertensive Disorder ◽  
Mortality Pattern ◽  
Male Predominance ◽  
Maternal Hypertension ◽  
Hypertensive Disorder Of Pregnancy

Background and objectives: Hypertensive disorder of pregnancy is a major cause of   maternal and neonatal mortality and morbidity worldwide. This study prospectively examined the immediate neonatal outcome of women with hypertensive disorder of pregnancy .Objectives were to study the effects of maternal hypertension on   APGAR score at birth and the need for neonatal resuscitation  as well as  to study neonatal morbidity profile and mortality pattern. Methods: Observational study was conducted on 125 babies born to mothers with hypertension in the neonatal intensive care unit of jubilee mission medical college. To study the effects of maternal hypertension and perinatal outcome, frequency and percentages were applied. Following parameters like prematurity, IUGR, low birth weight, hypoglycemia, hypocalcemia, hyperbilirubinemia will be studied .Chi square test will be applied for categorical variables and independent two sample t test will be applied for numerical variables. Results: Study population had male predominance.60% underwent LSCS.SGA babies maximum with eclampsia(45.5%),IUGR babies maximum with pre-eclampsia(9.4%).Prematurity seen in all babies born to eclamptic and 40.6% born to pre-eclamptic mothers(p-0.001).1 and 5minute APGAR were<7 in 15.9%,15.6%,18.2% and 12.2%,9.4%,9.1% of babies born to mothers with PIH, pre-eclampsia and eclampsia respectively. Other variables not statistically significant. Death was maximum in babies born to pre-eclamptic mothers (9.4 %). Conclusions: Maternal hypertension was associated with higher risk of adverse perinatal outcomes; necessitating need to strengthen prevention, early diagnosis and management of pregnancy-induced hypertension. Keywords: APGAR; prematurity; low birth weight; hypoglycemia; hyperbilirubinemia; hypocalcemia; respiratory distress  

scholarly journals Hypertensive disorders of pregnancy: A five-year review in Babcock University Teaching Hospital, Ilishan-Remo, Ogun State, Nigeria

2020 ◽  
Vol 3 (1) ◽  
pp. 67-72
Author(s):  
Olufemi Adebawojo ◽  
Adebayo Akadri ◽  
John Imaralu
Keyword(s):  
Cesarean Section ◽  
Teaching Hospital ◽  
University Teaching ◽  
Elective Cesarean Section ◽  
Delivery Mode ◽  
Hypertensive Disorder ◽  
Ogun State ◽  
Hypertensive Disorders ◽  
Hypertensive Disorder Of Pregnancy ◽  
The Mean

Objective: To determine the prevalence and outcome of hypertensive disorder of pregnancy in Babcock University Teaching Hospital, Ilishan-Remo, Ogun State Nigeria Method: This was a retrospective descriptive study of all documented cases of hypertensive disorder of pregnancy between the 1st of June 2012 and 31st May, 2017. Information such as age, parity, booking status, level of education, blood pressure at presentation, urinalysis at presentation, gestational age at presentation, and delivery, mode of delivery, baby’s birth weight was extracted from patients’ case files. Result: There were 1,118 deliveries during the study period out of which 55 (4.9%) patients had hypertensive disorders in pregnancy. The mean age was 31.5years ±48.1 and mean parity, 1.2± 1.1.  The mean systolic and diastolic blood pressures were 180.4 ± 1.88mmHg and 105.1± 1.5mmHg, respectively. Thirty-four (75.5%) of the women had preeclampsia/ eclampsia, while 7 (15.5%) had gestational hypertension. Most women were delivered preterm (22 patients, 48.7%).  The majority of them (33, 73.3%) were delivered by cesarean section, out of which 2 (4.4%) were elective cesarean section and 31 patients (68.8%) were emergency cesarean section. The case fatality rate was 1.8%. Conclusion: Pre-eclampsia was the most prevalent t hypertensive disorder of pregnancy.  It was more prevalent among primigravidae patients and the most common complication was preterm delivery. Strengthening antenatal care services will enable early identification of cases. Prompt referral of cases for specialist care will help in reducing the adverse outcomes associated with the condition.

CLINICAL CHARACTERISTICS AND FETO-MATERNAL OUTCOMES IN PREGNANT WOMEN WITH COVID -19 INFECTIONS

2021 ◽  
pp. 30-32
Author(s):  
Gulshan Bano ◽  
Anubha Prashad ◽  
Rakhee Soni ◽  
Mohammed Mishal
Keyword(s):  
Pregnant Women ◽  
Cesarean Delivery ◽  
Clinical Features ◽  
Clinical Characteristics ◽  
Maternal Outcomes ◽  
Hypertensive Disorder ◽  
Co Morbidity ◽  
Hypertensive Disorder Of Pregnancy ◽  
The Mean ◽  
In Pregnancy

Background and objectives:-COVID-19 is ongoing pandemic, caused by novel Corona Virus. There is very scarce information is available about clinical features and feto-maternal outcomes of COVID-19 in pregnancy. Therefore, this study was aimed to determine clinical characteristics and feto-maternal outcomes of pregnant women with COVID-19. Methods- In this retrospective study, we included all pregnant women admitted with COVID-19 over three months. Clinical features, laboratory ndings and feto-maternal outcomes were assessed.Results:-The mean age of the patients was 24 years. Hypertensive disorder of pregnancy was most common associated co-morbidity. Majority of patients (81%) were asymptomatic. Lymphocytopenia was seen in 58% of the patients and 47% had elevated levels of CRP. All patients who presented in rst trimester had spontaneous abortion. There is relatively higher rate of preterm birth (21%) and cesarean delivery(43%). All the neonates were tested negative for COVID-19. Conclusion;- There is relatively higher rate of cesarean delivery. Overall feto-maternal outcome was good and there was no evidence of vertical transmission.

Sign in / Sign up

Export Citation Format

Share Document