scholarly journals The General Surgery Residents Perception for the Training Program at the King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia

2016 ◽  
Vol 04 (01) ◽  
Author(s):  
Osman A Hamour
Keyword(s):  
Saudi Arabia ◽  
Training Program ◽  
General Surgery ◽  
Research Center ◽  
King Faisal Specialist Hospital

scholarly journals Assessing frequency and clinical outcomes of BRCA mutated ovarian cancer in Saudi women

BMC Cancer ◽  
2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Naela Agha ◽  
Bader Alshamsan ◽  
Sharifa Al-Farsi ◽  
Heba Aly Ateya ◽  
Fahad A. Almugbel ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Saudi Arabia ◽  
Clinical Outcomes ◽  
Gene Mutations ◽  
Patient Characteristics ◽  
Research Center ◽  
Frequency Pattern ◽  
Saudi Women ◽  
Platinum Sensitive ◽  
King Faisal Specialist Hospital

Abstract Purpose BRCA gene mutations (BRCAm) have an impact on patients’ characteristics and clinical outcomes of ovarian cancer (OC). The frequency and patterns of BRCAm vary among countries and ethnicities. There are limited data from Saudi Arabia (SA); thus, this study aims to determine the frequency, pattern, and impact on patient characteristics and outcomes of BRCAm OC compared to wild-type BRCA (BRCAw) in Saudi women. Methods This retrospective study evaluated women diagnosed with non-mucinous OC, fallopian tube, or peritoneal carcinoma who had BRCA status tested in an accredited lab between January 2016 and December 2017. The associations between various parameters and BRCAm were estimated using logistic regression. Statistical analysis performed with SPSS (Version 27). Result Sixty-one women with a median age of 52 at diagnosis were analyzed. Germline BRCA mutations were found in 41% of cases (25/61). The most common deleterious germline BRCA1 mutation was c.1140dupG (39%). Most women (72%) had no family history of cancers and 82% had advanced stage. Regardless of BRCA mutations, an optimal overall response rate (ORR) to first-line treatment has been achieved although most cases relapsed (84%) and the majority were platinum-sensitive relapse (85%). Higher ORR to subsequent lines and better survival were obtained in women with BRCA-mutation. Conclusion The prevalence of BRCAm of OC was higher in Saudi women compared to regional and most of the international figures. The better clinical outcomes of BRCAm women agreed with the reported evidence. Further studies on BRCA mutations of OC and genetic counseling are highly recommended. Trial registration Trial approved by the Institutional Review Board of King Faisal Specialist Hospital and Research Center (RAC # 2171137) and conducted at King Faisal Specialist Hospital and Research Center, PO Box 3354, Riyadh 11,211, Saudi Arabia.

scholarly journals Assessing Frequency and Clinical Outcomes of BRCA Mutated Ovarian Cancer in Saudi Women

2021 ◽  
Author(s):  
Naela Agha ◽  
Bader Alshamsan ◽  
Sharifa Al-Farsi ◽  
Heba Aly Ateya ◽  
Fahed A Almugbel ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Saudi Arabia ◽  
Clinical Outcomes ◽  
Brca Mutation ◽  
Brca1 Mutation ◽  
Research Center ◽  
Brca Mutations ◽  
Frequency Pattern ◽  
Saudi Women ◽  
King Faisal Specialist Hospital

Abstract Purpose: BRCA gene mutations (BRCAm) had an impact on patients' characteristics and clinical outcomes of ovarian cancer (OC). The frequency and patterns of BRCAm vary among countries and ethnicities. There are limited data from Saudi Arabia (SA); thus, this study aims to determine the frequency, pattern, and impact on patient characteristics and outcomes of BRCAm OC compared to wild-type BRCA (BRCAw) in Saudi women.Methods: This retrospective study evaluated women diagnosed with non-mucinous OC, fallopian tube, or peritoneal carcinoma who had BRCA status tested in an accredited lab between January 2016 and December 2017. The associations between various parameters and BRCAm were estimated using logistic regression. Statistical analysis performed with SPSS (Version 27). Result: Sixty-one women with a median age of 52 at diagnosis were analyzed. Germline BRCA mutations were found in 41% of cases (25/61). The most common deleterious germline BRCA1 mutation was c.1140dupG (39%). Most women (72%) had no family history of cancers and 82% had advanced stage. Regardless of BRCA mutations, an optimal overall response rate (ORR) to first-line treatment has been achieved although most cases relapsed (84%) and the majority were platinum-sensitive relapse (85%). Higher ORR to subsequent lines and better survival were obtained in women with BRCA-mutation.Conclusion: The prevalence of BRCAm of OC was higher in Saudi women compared to regional and most of the international figures. The better clinical outcomes of BRCAm women agreed with the reported evidence. Further studies on BRCA mutations of OC and genetic counseling are highly recommended.Trial registration number and The addresses of the institution at which the work was performed:Trial approved by the Institutional Review Board of King Faisal Specialist Hospital and Research Center (RAC # 2171137) and conducted at King Faisal Specialist Hospital and Research Center, PO Box 3354, Riyadh 11211, Saudi Arabia.

scholarly journals The effectiveness of a proposed training program based on active learning to develop teaching skills of Shari'a Sciences’ teachers and their attitudes towards it at the kingdom of Saudi Arabia: فاعلية برنامج تدريبي مقترح قائم على التعلّم النشط في تنمية المهارات التدريسية لدى معلمي العلوم الشرعية واتجاهاتهم نحوه في المملكة العربية السعودية

2019 ◽  
Vol 3 (27) ◽  
Author(s):  
Fahad Ayed Al Radaddi , Amal Mahmoud Ali ,   Iman Mohamed Ma
Keyword(s):  
Saudi Arabia ◽  
Active Learning ◽  
Secondary School ◽  
Training Program ◽  
Learning Strategies ◽  
Positive Impact ◽  
Teaching Skills ◽  
Kingdom Of Saudi Arabia ◽  
Before And After ◽  
Planning Implementation

Research Goal: To measure the effectiveness of the use of a proposed training program based on active learning to develop teaching skills of Shari'a Sciences’ teachers and their attitudes towards it at the kingdom of Saudi Arabia. The Research depended on the descriptive approach during building the program that based on active learning strategies, as assign experimental method when applying the program to identify its effectiveness in developing teaching of Shari'a Sciences’ teachers for the secondary school in the city of Medina and their attitudes toward it in teaching. Research instruments: The Card Note of teaching skills consisted of (45) sub-skill divided into three main areas which are (planning, implementation and evaluation). The measure of the attitude towards active learning in teaching included (26) phrases, therefore, the program is based on active learning in developing the teaching skills. After the researcher has checked the sincerity of research instruments, he began to be apply it to a stratified random sample, which consisted of (34) teachers of Shari'a Sciences’ teachers for the secondary school. The research contain a number of appropriate statistical methods, which are arithmetic averages, standard deviations, (T) test for the associated groups, the coefficient of Peerson, ETA square, the equation of the Blak, the coefficient of alpha Cronbach and the equation of Cooper. After conducting statistical analyzes, the research found the existence of Statistical differences among the average performance of the research sample in the Card Note of teaching skills in (planning, implementation and evaluation) Separated and combined in the light of active learning before and after the proposed training program for the benefit of the telemetric. In the light of the findings, the research recommended: Taking advantage of the current research program in training Shari'a Sciences’ teachers in different stages of education, especially Secondary School Teachers, because of its positive impact on the development of their teaching skills, and benefit from the list of teaching skills of the current research when assessing teachers' performance during service.   ، ، ، 

scholarly journals Molecular patterns of β-thalassemia mutations of Saudi patients referred to King Faisal Specialist Hospital and Research Center

2017 ◽  
Vol 8 (3) ◽  
pp. 99 ◽  
Author(s):  
Ayman Mashi ◽  
Haitham Khogeer ◽  
Adnan khyatte ◽  
Halah Abalkhail ◽  
Salem Khalil
Keyword(s):  
Research Center ◽  
King Faisal Specialist Hospital ◽  
Molecular Patterns ◽  
Saudi Patients

scholarly journals Incidence of gastric carcinoma at King Faisal Specialist Hospital- Jeddah Saudi Arabia: a hospital-based study

2016 ◽  
Vol 3 (2) ◽  
pp. 606-611
Author(s):  
Raha Alahmadi ◽  
Osman Hamour ◽  
Al-Enizi H ◽  
Tashkandi A
Keyword(s):  
Saudi Arabia ◽  
Gastric Carcinoma ◽  
King Faisal Specialist Hospital
Sign in / Sign up

Export Citation Format

Share Document