A High Order Compact Scheme for a Thermal Wave Model of Bio-Heat Transfer with an Interface

2018 ◽  
Vol 11 (2) ◽  
pp. 321-337 ◽  
Author(s):  
Suruchi Singh
2020 ◽  
Vol 30 (12) ◽  
pp. 5143-5167
Author(s):  
Moataz Alosaimi ◽  
Daniel Lesnic ◽  
Jitse Niesen

Purpose This study aims to at numerically retrieve five constant dimensional thermo-physical properties of a biological tissue from dimensionless boundary temperature measurements. Design/methodology/approach The thermal-wave model of bio-heat transfer is used as an appropriate model because of its realism in situations in which the heat flux is extremely high or low and imposed over a short duration of time. For the numerical discretization, an unconditionally stable finite difference scheme used as a direct solver is developed. The sensitivity coefficients of the dimensionless boundary temperature measurements with respect to five constant dimensionless parameters appearing in a non-dimensionalised version of the governing hyperbolic model are computed. The retrieval of those dimensionless parameters, from both exact and noisy measurements, is successfully achieved by using a minimization procedure based on the MATLAB optimization toolbox routine lsqnonlin. The values of the five-dimensional parameters are recovered by inverting a nonlinear system of algebraic equations connecting those parameters to the dimensionless parameters whose values have already been recovered. Findings Accurate and stable numerical solutions for the unknown thermo-physical properties of a biological tissue from dimensionless boundary temperature measurements are obtained using the proposed numerical procedure. Research limitations/implications The current investigation is limited to the retrieval of constant physical properties, but future work will investigate the reconstruction of the space-dependent blood perfusion coefficient. Practical implications As noise inherently present in practical measurements is inverted, the paper is of practical significance and models a real-world situation. Social implications The findings of the present paper are of considerable significance and interest to practitioners in the biomedical engineering and medical physics sectors. Originality/value In comparison to Alkhwaji et al. (2012), the novelty and contribution of this work are as follows: considering the more general and realistic thermal-wave model of bio-heat transfer, accounting for a relaxation time; allowing for the tissue to have a finite size; and reconstructing five thermally significant dimensional parameters.


1998 ◽  
Vol 15 (4) ◽  
pp. 580-584
Author(s):  
Ji Zhongzhen ◽  
Li Jing

Sign in / Sign up

Export Citation Format

Share Document