Metformin revisited: Does this regulator of AMP-activated protein kinase secondarily affect bone metabolism and prevent diabetic osteopathy

Antonio Desmond McCarthy; Ana María Cortizo; Claudia Sedlinsky

doi:10.4239/wjd.v7.i6.122

Metformin revisited: Does this regulator of AMP-activated protein kinase secondarily affect bone metabolism and prevent diabetic osteopathy

World Journal of Diabetes ◽

10.4239/wjd.v7.i6.122 ◽

2016 ◽

Vol 7 (6) ◽

pp. 122 ◽

Cited By ~ 23

Author(s):

Antonio Desmond McCarthy ◽

Ana María Cortizo ◽

Claudia Sedlinsky

Keyword(s):

Protein Kinase ◽

Bone Metabolism ◽

Amp Activated Protein Kinase ◽

Affect Bone Metabolism

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Caloric restriction and CB1 blockade activate AMP-activated protein kinase and mediate cardio-protection in a model of premature cardiac senescence

The Thoracic and Cardiovascular Surgeon ◽

10.1055/s-0034-1367259 ◽

2014 ◽

Vol 62 (S 01) ◽

Author(s):

B. Niemann ◽

H. Issa ◽

L. Li ◽

R.-E. Silber ◽

A. Böning ◽

...

Keyword(s):

Protein Kinase ◽

Caloric Restriction ◽

Cardio Protection ◽

Amp Activated Protein Kinase

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Activators of AMP-activated protein kinase regulate adipocyte aldosterone secretion and mineralocorticoid receptor signalling

Endocrine Abstracts ◽

10.1530/endoabs.37.oc5.3 ◽

2015 ◽

Author(s):

Anna White ◽

Aurelie Nguyen Dinh Cat ◽

Augusto Montezano ◽

Ian Salt ◽

Rhian Touyz

Keyword(s):

Protein Kinase ◽

Mineralocorticoid Receptor ◽

Aldosterone Secretion ◽

Receptor Signalling ◽

Amp Activated Protein Kinase

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Chronic activation of AMP-activated protein kinase increases monocarboxylate transporter 2 and 4 expression in skeletal muscle

Journal of Animal Science ◽

10.2527/jas2017.1457 ◽

2017 ◽

Vol 95 (8) ◽

pp. 3552

Author(s):

E. M. England ◽

H. Shi ◽

S. K. Matarneh ◽

E. M. Oliver ◽

E. T. Helm ◽

...

Keyword(s):

Skeletal Muscle ◽

Protein Kinase ◽

Monocarboxylate Transporter ◽

Chronic Activation ◽

Amp Activated Protein Kinase

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Faculty Opinions recommendation of AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1002927.191006 ◽

2003 ◽

Author(s):

Bruce Kemp

Keyword(s):

Protein Kinase ◽

Protein Stability ◽

Transcriptional Activity ◽

Dimer Formation ◽

Amp Activated Protein Kinase

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Faculty Opinions recommendation of Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1007772.194210 ◽

2003 ◽

Author(s):

Bruce Kemp

Keyword(s):

Protein Kinase ◽

Amp Activated Protein Kinase

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Faculty Opinions recommendation of Evaluation of the role of AMP-activated protein kinase and its downstream targets in mammalian hibernation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1022352.346456 ◽

2005 ◽

Author(s):

Bruce Kemp

Keyword(s):

Protein Kinase ◽

Downstream Targets ◽

Amp Activated Protein Kinase ◽

Mammalian Hibernation

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Faculty Opinions recommendation of Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1047636.497621 ◽

2006 ◽

Author(s):

Michael Clark

Keyword(s):

Protein Kinase ◽

Ldl Receptor ◽

Accelerated Atherosclerosis ◽

Amp Activated Protein Kinase ◽

Deficient Mice

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Faculty Opinions recommendation of AMP-activated protein kinase phosphorylates and desensitizes smooth muscle myosin light chain kinase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1115415.571445 ◽

2008 ◽

Author(s):

Steve Rattigan

Keyword(s):

Smooth Muscle ◽

Protein Kinase ◽

Light Chain ◽

Myosin Light Chain Kinase ◽

Myosin Light Chain ◽

Smooth Muscle Myosin ◽

Amp Activated Protein Kinase ◽

Muscle Myosin

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Faculty Opinions recommendation of Structural insight into the autoinhibition mechanism of AMP-activated protein kinase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1161309.621803 ◽

2009 ◽

Author(s):

David Grahame Hardie

Keyword(s):

Protein Kinase ◽

Structural Insight ◽

Amp Activated Protein Kinase ◽

Insight Into

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Faculty Opinions recommendation of AMP-activated protein kinase response to contractions and treatment with the AMPK activator AICAR in young adult and old skeletal muscle.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1164233.624931 ◽

2009 ◽

Author(s):

Roberto Bottinelli

Keyword(s):

Skeletal Muscle ◽

Young Adult ◽

Protein Kinase ◽

Amp Activated Protein Kinase

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