scholarly journals Colorimetric determination of Chloramphenicol and metronidazole in pharmaceutical formulations after schiff-base formation with vanillin and anisaldehyde

2003 ◽  
Vol 9 (3) ◽  
Author(s):  
B. H. Ahmed ◽  
J. O. Onah
Keyword(s):  
Schiff Base ◽  
Pharmaceutical Formulations ◽  
Colorimetric Determination ◽  
Schiff Base Formation ◽  
Base Formation

Determination of Amphetamine by Schiff Base Formation and Quantitative Gas-Liquid Chromatography

1975 ◽  
Vol 58 (6) ◽  
pp. 1174-1177
Author(s):  
Charles C Clark
Keyword(s):  
Schiff Base ◽  
Internal Standard ◽  
Chromatographic Determination ◽  
Solid Matrix ◽  
Gas Liquid Chromatography ◽  
Solid Dosage Forms ◽  
Solid Dosage ◽  
Schiff Base Formation ◽  
Base Formation

Abstract A procedure was developed to determine amphetamine salts in solid dosage forms. Amphetamine was extracted from the solid matrix with dilute hydrochloric acid and reacted with cyclohexanone in a strongly basic aqueous methanolic solution. The Schiff base reaction product was extracted with hexane for gas chromatographic determination. Reaction time and optimum conditions were studied. Phcnethylamine, similarly treated, was used as an internal standard. Results compared favorably with those obtained by using USP methods.

Predictive chirality sensing via Schiff base formation

2019 ◽  
Vol 17 (27) ◽  
pp. 6699-6705 ◽  
Author(s):  
Samantha L. Pilicer ◽  
Michele Mancinelli ◽  
Andrea Mazzanti ◽  
Christian Wolf
Keyword(s):  
Schiff Base ◽  
Absolute Configuration ◽  
Chiral Amines ◽  
Schiff Base Formation ◽  
Base Formation

Determination of ee and absolute configuration of chiral amines is achieved with a sterically crowded Schiff base sensor.

Colorimetric Determination of Amoxicillin in Pure and some Pharmaceutical Formulations Via Reaction with Potassium Permanganate as Oxidant Reagent

2019 ◽  
Vol 10 (02) ◽  
Author(s):  
Abbas Shebeeb Al-kadumi ◽  
Sahar Rihan Fadhel ◽  
Mohammed Abdullah Ahmed ◽  
Luma Amer Musa
Keyword(s):  
Potassium Permanganate ◽  
Pharmaceutical Preparations ◽  
Pharmaceutical Formulations ◽  
Atomic Emission ◽  
Basic Medium ◽  
Photometric Method ◽  
Colorimetric Determination ◽  
Spectrophotometric Methods ◽  
Label Claim

We proposed two simple, rapid, and convenient spectrophotometric methods are described for the determination of Amoxicillin in bulk and its pharmaceutical preparations. They are based on the measurement of the flame atomic emission of potassium ion (in first method) and colorimetric determination of the green colored solution for manganite ion at 610 nm formed after reaction of Amoxicillin with potassium permanganate as oxidant agent (in the second method) in basic medium. The working conditions of the methods were investigated and optimized. Beer's law plot showed a good correlation in the concentration range of 5-45 μg/ml. The detection limits and relative standared deviations were (2.573, 2.814 μg/ml) (2.137, 2.498) for the flame emission photometric method and (1.844, 2.016 μg/ml) (1.645,1.932) for colorimetric methods for capsules and suspensions respectively. The methods were successfully applied to the determination of Amoxicillin in capsules and suspensions, and the obtained results were in good agreement with the label claim. No interference was observed from the commonly encountered additives and expectancies.

Schiff Base Formation upon Complexation of Tris(acetylacetonato)iron with N[(CH2CH2NH2)(CH2CH2OH)(CH2CH2CH2OH)]

2004 ◽  
Vol 630 (13-14) ◽  
pp. 2558-2561 ◽  
Author(s):  
F. Ekkehardt Hahn ◽  
Christoph Jocher ◽  
Thomas L�gger ◽  
Tania Pape
Keyword(s):  
Schiff Base ◽  
Schiff Base Formation ◽  
Base Formation
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