scholarly journals EFFICACY OF ACETIC ACID VERSUS CIPROFLOXACIN EAR DROPS IN ACHIEVING DRY EARS IN CHRONIC SUPPURATIVE OTITIS MEDIA IN ADULT POPULATION OF ISLAMABAD, PAKISTAN: A NON-RANDOMIZED CONTROL TRIAL

2020 ◽  
Vol 17 (3) ◽  
pp. 90-94
Author(s):  
Arslan Akhtar ◽  
Syed Maisam Ali ◽  
Syed Ali Naqi ◽  
Tabassum Aziz ◽  
Wajih-ud-din Shinwari ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Otitis Media ◽  
Adult Population ◽  
Chronic Suppurative Otitis Media ◽  
Control Group ◽  
Chi Square ◽  
Suppurative Otitis Media ◽  
Acid Versus ◽  
Experimental Group ◽  
Ear Drops

Background: Chronic suppurative otitis media (CSMO) is an important cause of preventable hearing loss, particularly in developing world. The objective of this trial was to compare efficacy of 2% acetic acid versus 0.3% ciprofloxacin ear drops in achieving dry ears in CSMO in adult population of Islamabad, Pakistan. Materials & Methods: This trial was conducted at Department of ENT, HBS Medical College, Islamabad, Pakistan from March 2018 to February 2019. With alpha 5%, beta 20% and power of study 80%, sample size was calculated 47 for each group. All adult patients of CSOM, having ear discharge for more than three months were eligible. Patients with aural poly, external auditory canal pathology, ear malignancy, having mastoid surgery in preceding 12 months or having used antibiotics in last one week were excluded. Experimental group received 2% acetic acid, twice daily while control group received 0.3% ciprofloxacin eardrops twice daily. At two weeks, achievement of dry ears was noted. Sex and age in years were matching variables. Primary end point was achieving dry ears, which was compared between the two groups using McNemar chi-square test. Results: Experimental group included 30 (63.8%) men and 17 (36.2%) women and control group included 32 (68%) men and 15 (32%) women. Mean age of experimental group 36±2.14 years was matching to the control group 36±2.59 years. Dry ears were achieved in 35 (74.47%) patients in experimental group and in 11 (23.40%) patients in control group. The efficacy of 2% acetic acid was significantly higher than 0.3% ciprofloxacin eardrops in achieving dry ears (p

Efficacy of Acetic Acid Irrigation in Management of Chronic Suppurative Otitis Media “A Prospective Study

2021 ◽  
Vol 15 (10) ◽  
pp. 3300-3303
Author(s):  
Nasir Riaz ◽  
Shakaib Faiz ◽  
Danish Hassnain ◽  
Ayesha Fayyaz ◽  
Tarique Khan ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Suppurative Otitis Media ◽  
Acid Versus ◽  
Acid Irrigation ◽  
Group A ◽  
Group B ◽  
A Prospective Study ◽  
Systemic Antibiotics

Background: Prior to surgical management of chronic suppurative otitis media (CSOM) for the dry ear medical management is necessary. CSOM is a biofilm disease and due to this has antibiotic resistance. The pillar of its treatment included aural cleaning according to standard protocols, application of topical germ free antiseptic and use of antimicrobials. Acetic acid due to its ability in reducing the pH may be effective in reducing the growth of microorganisms. Objective: The aim of the study was to compare the efficacy of irrigation with acetic acid versus systemic antibiotics in CSOM patients. Materials & Methods: A total of 134 patients, who came to the ENT department of Sheikh Zayed Hospital, Lahore between 1st April 2020 to 30th September 2020, who had CSOM, of age 15 to 55 years and both genders were included in the study. The patients were divided randomly into two groups. Group A patients received aural toilets and irrigation with acetic acid and Group B received 500 mg of ciprofloxacin twice a day for 2 weeks. Results: The mean age (in years) of the patients in Group A was 37.45±7.32 and in Group B, it was 37.96±7.57. The efficacy of irrigation with acetic acid versus systemic antibiotics was 89.55% and 68.66% respectively and this difference between the two groups was found to be statistically significant (p=0.003). Conclusion: Irrigation with acetic acid was better than systemic antibiotics in managing patients with CSOM. Key words: Acetic acid, CSOM, Middle ear

scholarly journals Anterior epitympanic attic antrum space obstruction and symptom onset associated with myringosclerosis in benign chronic suppurative otitis media

2020 ◽  
Vol 8 (6) ◽  
pp. 2013
Author(s):  
Zulfikar Naftali ◽  
Suprihati . ◽  
Dharmana E. ◽  
Setyawan H.
Keyword(s):  
Tympanic Membrane ◽  
Otitis Media ◽  
Middle Ear ◽  
Symptom Onset ◽  
Chronic Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Control Group ◽  
Chi Square ◽  
Suppurative Otitis Media ◽  
Control Approach

Background: The AAA (Anterior epitympanic, Attic, and Antrum) space is the space between the mastoid and middle ear which functions to balance the pressure in both organs (buffer). Pathological tissue in the AAA cavity due to chronic infection would disrupt the buffer function and could change the morphology of the mucosa in the tympanic membrane and middle ear. Obstruction in the AAA space measured subjectively by observing the smoothness of the flow using saline solution has been shown to be associated with a plaque in the tympanic membrane (myringosclerosis) in Chronic Otitis Media (COM) patients. This study aims to determine the relationship between AAA space obstructions with myringosclerosis using CT-Scan for an objective result.Methods: Retrospective study with case-control approach used in this study. Case criterias are Chronic Suppurative Otitis Media (CSOM) patients with myringosclerosis, both men and women and age 15-50 years, while the control group are benign CSOM patients without myringosclerosis. Data were analyzed with the chi-square test to prove the association between the AAA space status and length of symptom onset with myringosclerosis.Results: During January 2017-December 2019 there were 33 respondents, 19 cases and 14 controls, 21 men and 12 women with an average age of 35 years (cases) and 23.5 years (control). The length of symptom onset more than 5 years (p <0.05, OR 6.94 with CI 0.5-1.5) and AAA space obstruction (p <0.05 OR 34.25 with CI 0.8-1.8) has been shown to be associated with myringosclerosis in people with benign CSOM.Conclusions: AAA space obstruction and symptom onset more than 5 years significantly associated with myringosclerosis. 

The effect of topical ciprofloxacin and steroid-containing ear drops for chronic suppurative otitis media on the internal ear

2009 ◽  
Vol 267 (1) ◽  
pp. 35-41 ◽  
Author(s):  
Zeliha Kapusuz ◽  
Erol Keles ◽  
Hayrettin Cengiz Alpay ◽  
Turgut Karlidag ◽  
Irfan Kaygusuz ◽  
...  
Keyword(s):  
Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Suppurative Otitis Media ◽  
Ear Drops

scholarly journals Impact of Educational Program on the Management of Chronic Suppurative Otitis Media among Children

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Yousseria Elsayed Yousef ◽  
Essam A. Abo El-Magd ◽  
Osama M. El-Asheer ◽  
Safaa Kotb
Keyword(s):  
Risk Factors ◽  
Otitis Media ◽  
Educational Program ◽  
Chronic Suppurative Otitis Media ◽  
Control Group ◽  
Suppurative Otitis Media ◽  
Complete Cure ◽  
Group I ◽  
Group Ii ◽  
The Impact

Background. Chronic suppurative otitis media (CSOM) remains one of the most common childhood chronic infectious diseases worldwide, affecting diverse racial and cultural groups in both developing and industrialized countries.Aim of the Study. This study aimed to assess the impact of educational program on the management of children with CSOM.Subjects and Methods. An experimental study design was used. This study included 100 children of both sexes of 2 years and less of age with CSOM. Those children were divided into 3 groups: group I: it involved 50 children with CSOM (naive) who received the designed educational program; control group: it involved 50 children who were under the traditional treatment and failed to respond; group II: those children in the control group were given the educational program and followed up in the same way as group I and considered as group II.Tools of the Study. Tool I is a structured questionnaire interview sheet for mothers. It consists of four parts: (1) personal and sociodemographic characteristics of child and (2) data about risk factors of otitis media (3) assessment of maternal practice about care of children with suppurative otitis medi (4) diagnostic criteria for suppurative otitis media. Tool II is the educational program: an educational program was developed by the researchers based on the knowledge and practices needs. This study was carried out through a period of 9 months starting from September 2013 to May 2014. The educational program was implemented for mothers of children with CSOM in the form of 5 scheduled sessions at the time of diagnosis, after one week, 1, 3, and 6 months.Results. There were significant differences between children who received the educational program and control group regarding the response to treatment after one and 3 months. The percentages of complete cure increased progressively 32%, 60%, and 84% after 1, 3, and 6 months in group I while they were 24%, 44%, and 64% in group II, respectively. Cure (dry perforation) was 64%, 36%, and 12% among children of group I after 1, 3, and 6 months while it was 64%, 44%, and 24% in group II, respectively. The percentages of compliance to the educational program improved with time in both groups: 44%, 64%, and 80% in group I and 32%, 48%, and 56% in group II after 1, 3, and 6 months, respectively. The percentages of cure were statistically significantly higher among children with complete compliance with the educational program in both groups in comparison to those with incomplete compliance (P= 0.000 for both).Conclusions. From this study we can conclude that the majority of children with CSOM had one or more risk factors for occurrence of the disease; the educational program is effective for management of CSOM (whether cure or complete cure); the higher the compliance of mothers with the program the higher the response rate; regular followup and explanation of the importance of the program played an important role in the compliance with the program.

Effect of chronic suppurative otitis media on distortion product otoacoustic emission input–output functions in conventional and ultra-high frequencies

2019 ◽  
Vol 133 (11) ◽  
pp. 995-1004
Author(s):  
S I Kirubaharane ◽  
S Palani ◽  
A Alexander ◽  
A Sreenivasan
Keyword(s):  
Otitis Media ◽  
Otoacoustic Emissions ◽  
Otoacoustic Emission ◽  
Chronic Suppurative Otitis Media ◽  
Distortion Product Otoacoustic Emissions ◽  
Control Group ◽  
Clinical Group ◽  
Distortion Product Otoacoustic Emission ◽  
Suppurative Otitis Media ◽  
Distortion Product

AbstractBackgroundDetection and valid measurements of distortion product otoacoustic emissions are not influenced by cochlear status alone, but also by middle-ear status. There is a need to understand the use of ultra-high frequency distortion product otoacoustic emissions in cases of abnormal distortion product otoacoustic emission findings for conventional frequencies related to the middle-ear condition.MethodThe present study investigated distortion product otoacoustic emission input–output functions in conventional and ultra-high frequencies in: 37 adults with chronic suppurative otitis media (clinical group) and 37 adults with normal hearing sensitivity (control group).ResultsThere were significant reductions in distortion product otoacoustic emission amplitude and mean signal-to-noise ratio in the clinical group compared to the control group, especially for conventional frequencies.ConclusionThere was a significant reduction in the rate of ears with measurable distortion product otoacoustic emissions in the clinical group, especially for conventional frequencies. The effect of chronic suppurative otitis media was more pronounced in the conventional frequency range compared to the smaller effect seen in the ultra-high frequency range.

Biofilm presence in humans with chronic suppurative otitis media

2009 ◽  
Vol 141 (5) ◽  
pp. 567-571 ◽  
Author(s):  
Michael Robert Lee ◽  
Karen Sue Pawlowski ◽  
Amber Luong ◽  
Alexis Dorian Furze ◽  
Peter Sargent Roland
Keyword(s):  
Otitis Media ◽  
Middle Ear ◽  
Group Versus ◽  
Laser Scanning Microscopy ◽  
Chronic Suppurative Otitis Media ◽  
Control Group ◽  
Middle Ear Surgery ◽  
Suppurative Otitis Media ◽  
Female Ratio ◽  
Significant Difference

Objective: To study the presence of biofilm formation in humans with chronic suppurative otitis media (CSOM). Study Design: Cross-sectional study. Setting: Tertiary academic hospital. Subjects and Methods: Patients undergoing middle ear surgery between July 2006 and March 2008. Tissue samples were obtained from 25 patients, of which 20 specimens were successfully processed for this study. The remaining samples were not analyzed due to sample damage or loss during preparation. Of the 20 specimens studied, 10 were harvested as the experimental group from patients with CSOM and the other 10 harvested as controls from patients undergoing otologic surgery for acoustic neuroma, cochlear implant, or routine tympanoplasty. Ages ranged from 26 to 74 years (mean 45 yrs). Male-to-female ratio was 2:3. Scanning electron microscopy and confocal laser scanning microscopy were used to identify the presence of biofilms. Live-dead staining was used to assess whether bacteria present were viable. The outcome measured was the presence of adherent biofilms on middle ear mucosa. Results: Biofilms were present in six of 10 samples (60%) from the CSOM group, but only in one of 10 control samples (10%). Comparative analysis revealed a statistically significant difference ( P < 0.05) in the presence of biofilms in specimens from the CSOM group versus the control group. Conclusion: Biofilms were statistically more common in patients with CSOM compared with control patients.

Systemic absorption of gentamicin ear drops

1997 ◽  
Vol 111 (10) ◽  
pp. 960-962 ◽  
Author(s):  
K. M. J. Green ◽  
D. W. P. Lappin ◽  
J. W. A. Curley ◽  
J. P. de Carpentier
Keyword(s):  
Otitis Media ◽  
Otitis Externa ◽  
Chronic Suppurative Otitis Media ◽  
Systemic Absorption ◽  
Suppurative Otitis Media ◽  
Ear Drops

AbstractAminoglycoside-containing topical preparations are commonly used in the treatment of chronic suppurative otitis media and otitis externa. We report a case where systemic absorption of topical Gentisone HC™ occurred producing a serum gentamicin level of 6.2 μg/ml.

scholarly journals Influence of Tympanosclerosis on Graft Uptake and Hearing Status in Patients Undergoing Underlay Myringoplasty

1970 ◽  
Vol 7 (2) ◽  
pp. 116-119
Author(s):  
PL Prasad ◽  
H Bhattarai
Keyword(s):  
Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Control Group ◽  
P Value ◽  
Suppurative Otitis Media ◽  
Hearing Gain ◽  
Hearing Status ◽  
Health Research Council ◽  
And Control

Background: To assess the influence of tympanosclerosis on graft uptake and hearing status in patients undergoing underlay myringoplasty. Methods: Patients ≥12 years of age with the diagnosis of chronic suppurative otitis media tubo-tympanic type were included in this study. All patients participated in the study had undergone pre and postoperative pure tone audiometric evaluation and were divided into two groups, a study and a control, depending on the presence or absence of tympanosclerotic plaques. All patients underwent underlay myringoplasty and follow up was done after 10 weeks to note graft uptake and postoperative hearing evaluation. Results: Graft uptake was noted to be 96.1% in study group and 94.9% in control group. Similarly, graft uptake was noted in 96.36% where tympanosclerotic plaques were completely removed and in 95.23% where tympanosclerotic plaques were either partially removed or left as such. Post 0perative average hearing gain in study and control group was 12.1dB and 15.9dB respectively. While comparing postoperative hearing gain in cases where tympanosclerotic plaques were completely removed to those in whom tympanosclerotic plaques were either completely removed or left as such, it was 12.31dB in former and 13.67dB in later group, which was statistically non significant with P value of 0.83. Conclusions: Tympanosclerotic plaques, if removed as far as practicable, has no effect on either graft uptake and post operative hearing results in patient under going underlay myringoplasty. Key words: chronic suppurative otitis media tubo tympani type; puretone; audiogram; tympanosclerosis. DOI: 10.3126/jnhrc.v7i2.3019 Journal of Nepal Health Research Council Vol.7(2) Apr 2009 116-119

Sign in / Sign up

Export Citation Format

Share Document