scholarly journals Intestinal Strictures Post-Necrotising Enterocolitis: Clinical Profile and Risk Factors

2014 ◽  
Vol 3 (4) ◽  
Author(s):  
Nilkant Phad ◽  
Amit Trivedi ◽  
David Todd ◽  
Anil Lakkundi
Keyword(s):  
Risk Factors ◽  
Bowel Resection ◽  
Significant Proportion ◽  
Acute Stage ◽  
Necrotising Enterocolitis ◽  
Clinical Profile ◽  
Prolonged Hospitalisation ◽  
X Ray ◽  
Intestinal Stricture ◽  
Median Interval

Background: Intestinal stricture is an important complication of necrotising enterocolitis (NEC). We aimed to describe clinical profile and identify the risk factors for post-NEC intestinal strictures.Method: A retrospective study of infants with NEC over 10 year period.Results: Of the 61 infants with NEC, 18 (29.5%) developed intestinal strictures. Leucocytosis and longer length of bowel resection during acute stage of NEC was associated with a later diagnosis of intestinal stricture. Infants with NEC who did not develop stricture had non-specific intestinal dilatation on abdominal x-ray during acute NEC. Intestinal strictures were diagnosed at a median interval of 34 days after NEC. Majority of strictures (67%) occurred in the colon. A significant proportion (77%) of infants with intestinal stricture had associated co-morbidities. No mortality occurred in infants with intestinal strictures.Conclusion: The incidence of post-NEC intestinal stricture is high but development of stricture is difficult to predict. Leucocytosis during NEC and length of bowel resected at surgery may be associated with development of post-NEC intestinal stricture. A substantial number of infants with post-NEC intestinal stricture fail to thrive, have co-morbidities and need prolonged hospitalisation.

scholarly journals A STUDY ON CLINICAL PROFILE OF THE PATIENTS WITH CONGESTIVE HEART FAILURE

2020 ◽  
pp. 76-78
Author(s):  
Dharmendra Prasad ◽  
Mahendra Kumar ◽  
Raj Kumar Deepak ◽  
Sumit Kumar ◽  
Debarshi Jana
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Ventricular Hypertrophy ◽  
Prospective Observational Study ◽  
Left Ventricular ◽  
Clinical Profile ◽  
X Ray ◽  
Medical College ◽  
Multiple Risk Factors ◽  
Chest X Ray

Background: Heart failure (HF) is a common cardiovascular condition whose prevalence and incidence is increasing in the recentpast. Multiple risk factors involved in its genesis makes it more complex in the prevention and management. Objective: The present study aimed to assess the clinical profile of the patients suffering with heart failure. Methods: Prospective observational study was undertaken among the patients admitted in the Medical unit of Govt. Medical College and Hospital, Bettiah during October 2018 and September 2019. Patients fulfilling EuropeanSociety of Cardiology (ESC) criteria of HF were included in the study. Prevalence of congestive HF was estimated based on community study and hospital OPD. Results: Smoking, alcoholism, ischemic heart disease and hypertension were the leading risk factors in developing HF. Breathlessness(100%), swelling of the feet (92.3%), cough (57.7%) and palpitation (50%) were the most common symptoms observed inthe patients. Oedema feet (100%), basal crepitations (80.3%), raised Jugular Venous Distention (JVD) (57.7%) and S3 (57.7%)were the leading signs in the patients. Chest X-ray (CXR) findings indicate that 76.9% of the patients reported with increasedCardiothoracic ratio. Arrhythmias (predominantly AF-19.2%) and Left Ventricular Hypertrophy (LVH) accounted for 26.9% each. The prevalence of HF was estimated to be in between 0.51 to 27.27 respectively.

scholarly journals Prevalence, risk factors and clinical profile of patients with cardioembolic stroke in South India: a five-year prospective study

2020 ◽  
Vol 7 (7) ◽  
pp. 2708
Author(s):  
Sandhya Manorenj ◽  
Sudhakar Barla ◽  
Srikant Jawalker
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Prospective Study ◽  
Significant Proportion ◽  
Older Age ◽  
Clinical Profile ◽  
Cardioembolic Stroke ◽  
P Value ◽  
Age Group ◽  
Male Predominance

Background: Stroke is the second leading cause of mortality and morbidity worldwide. Cardioembolic stroke accounts for 15-30% of Ischemic stroke. There have been very few clinical studies on cardioembolic stroke, especially from India. Our aim was to provide a demographic, risk factor and clinical profile of patients with cardioembolic stroke in South India.Methods: A prospective study was conducted at the Neurology Inpatient Department over a period of 5 years from January 2013 to January 2018 collecting necessary information and data from all cases diagnosed as cardioembolic stroke.Results: 651 patients were diagnosed to have acute Ischemic stroke. Of the 76 patients (11.6%) diagnosed with cardioembolic stroke, 35 (46%) were females. Mean age was 53.5±12.2 years. Occurrence of cardioembolic stroke was seen to be higher (71% vs 28.9%, p value<0.0001) in patients of older age group (46 years or more). A significant proportion of patients of the older age group (37%) had hypertension (p value=0.0048). Coronary artery disease (CAD) was the most prevalent cardiac disorder, observed in 42 patients (55.2%), valvular heart disease in 22 patients (28.9%) and atrial fibrillation in 14 patients (18.4%). Limb weakness (84.2%) and Middle Cerebral Artery (MCA) territory (73.6%) infarct were observed in majority of the patients.Conclusions: Prevalence of cardioembolic stroke in this region is lower than reported worldwide. While male predominance of cardioembolic stroke was noted, old age and hypertension were the major vascular risk factors identified. CAD was the major source of cardioembolism.

Statin-induced adverse effects – facts and genes

2013 ◽  
Vol 154 (3) ◽  
pp. 83-92
Author(s):  
Mariann Harangi ◽  
Noémi Zsíros ◽  
Lilla Juhász ◽  
György Paragh
Keyword(s):  
Risk Factors ◽  
Single Nucleotide Polymorphisms ◽  
Adverse Effects ◽  
Adverse Events ◽  
Statin Therapy ◽  
Significant Proportion ◽  
Gene Mutations ◽  
Nucleotide Polymorphisms ◽  
Serious Adverse Events ◽  
Single Nucleotide

Statin therapy is considered to be safe and rarely associated with serious adverse events. However, a significant proportion of patients on statin therapy show some degree of intolerance which can lead to decreased adherence to statin therapy. The authors summarize the symptoms, signs and frequencies of the most common statin-induced adverse effects and their most important risk factors including some single nucleotide polymorphisms and gene mutations. Also, they review the available approaches to detect and manage the statin-intolerant patients. Orv. Hetil., 2013, 154, 83–92.

OSTEOPOROSIS AND RISK FACTORS IN THE PATIENTS ON CHRONIC HEMODIALYSIS

2015 ◽  
pp. 50-58
Author(s):  
Thi Dung Nguyen ◽  
Tam Vo
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Bone Density ◽  
Region Of Interest ◽  
Cross Sectional Study ◽  
Chronic Hemodialysis ◽  
Cross Sectional ◽  
X Ray ◽  
Density Reduction

Background: The patients on hemodialysis have a significantly decreased quality of life. One of many problems which reduce the quality of life and increase the mortality in these patients is osteoporosis and osteoporosis associated fractures. Objectives: To assess the bone density of those on hemodialysis by dual energy X ray absorptiometry and to examine the risk factors of bone density reduction in these patients. Patients and Method: This is a cross-sectional study, including 93 patients on chronic hemodialysis at the department of Hemodialysis at Cho Ray Hospital. Results: Mean bone densities at the region of interest (ROI) neck, trochanter, Ward triangle, intertrochanter and total neck are 0.603 ± 0.105; 0.583 ± 0.121; 0.811 ± 0.166; 0.489 ± 0.146; 0.723 ± 0.138 g/cm2 respectively. The prevalences of osteoporosis at those ROI are 39.8%, 15.1%; 28%; 38.7%; and 26.9% respectively. The prevalences of osteopenia at those ROI are 54.8%; 46.3%; 60.2%; 45.2% and 62.7% respectively. The prevalence of osteopososis in at least one ROI is 52.7% and the prevalence of osteopenia in at least one ROI is 47.3%. There are relations between the bone density at the neck and the gender of the patient and the albuminemia. Bone density at the trochanter is influenced by gender, albuminemia, calcemia and phosphoremia. Bone density at the intertrochanter is affected by the gender. Bone density at the Ward triangle is influenced by age and albuminemia. Total neck bone density is influenced by gender, albuminemia and phosphoremia. Conclusion: Osteoporosis in patients on chronic hemodialysis is an issue that requires our attention. There are many interventionable risk factors of bone density decrease in these patients. Key words: Osteoporosis, DEXA, chronic renal failure, chronic hemodialysis

scholarly journals Hydrothermal Synthesis of Iridium-Substituted NaTaO3 Perovskites

Nanomaterials ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1537
Author(s):  
David L. Burnett ◽  
Christopher D. Vincent ◽  
Jasmine A. Clayton ◽  
Reza J. Kashtiban ◽  
Richard I. Walton
Keyword(s):  
Significant Proportion ◽  
Edge Length ◽  
Perovskite Oxide ◽  
Hydrogen Yield ◽  
Orthorhombic Space Group ◽  
X Ray ◽  
Profile Fitting ◽  
Transmission Electron ◽  
Scanning Transmission ◽  
One Step

Iridium-containing NaTaO3 is produced using a one-step hydrothermal crystallisation from Ta2O5 and IrCl3 in an aqueous solution of 10 M NaOH in 40 vol% H2O2 heated at 240 °C. Although a nominal replacement of 50% of Ta by Ir was attempted, the amount of Ir included in the perovskite oxide was only up to 15 mol%. The materials are formed as crystalline powders comprising cube-shaped crystallites around 100 nm in edge length, as seen by scanning transmission electron microscopy. Energy dispersive X-ray mapping shows an even dispersion of Ir through the crystallites. Profile fitting of powder X-ray diffraction (XRD) shows expanded unit cell volumes (orthorhombic space group Pbnm) compared to the parent NaTaO3, while XANES spectroscopy at the Ir LIII-edge reveals that the highest Ir-content materials contain Ir4+. The inclusion of Ir4+ into the perovskite by replacement of Ta5+ implies the presence of charge-balancing defects and upon heat treatment the iridium is extruded from the perovskite at around 600 C in air, with the presence of metallic iridium seen by in situ powder XRD. The highest Ir-content material was loaded with Pt and examined for photocatalytic evolution of H2 from aqueous methanol. Compared to the parent NaTaO3, the Ir-substituted material shows a more than ten-fold enhancement of hydrogen yield with a significant proportion ascribed to visible light absorption.

Clinical Profile, Risk-Factors, and Outcome of Rotaviral Diarrhea and Non-rotaviral Diarrhea Among Under-Five Children at Cuttack, Odisha, India

2021 ◽  
Author(s):  
Subal Kumar Pradhan ◽  
Sumanta Panigrahi ◽  
Pooja Sagar Padhi ◽  
Arjun Sajeev ◽  
Aravind Dharmaraj ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clinical Profile ◽  
Under Five ◽  
Under Five Children

scholarly journals Clinical profile, risk factors and severity in patients with pediatric arterial ischemic stroke

2015 ◽  
Vol 357 ◽  
pp. e441
Author(s):  
M. Hidalgo ◽  
D. Munoz ◽  
M. Troncoso ◽  
S. Lara ◽  
C. Mateluna ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Clinical Profile ◽  
Arterial Ischemic Stroke

Predictors of Psychiatric Morbidity in Cancer Patients

1994 ◽  
Vol 165 (5) ◽  
pp. 593-598 ◽  
Author(s):  
Judy Harrison ◽  
Peter Maguire
Keyword(s):  
Risk Factors ◽  
Cancer Patients ◽  
Psychiatric Morbidity ◽  
Significant Proportion ◽  
Cross Sectional Study ◽  
Future Research ◽  
Cross Sectional ◽  
Appropriate Treatment ◽  
Study Designs ◽  
Patients Experience

BackgroundA significant proportion of cancer patients experience psychiatric morbidity in association with diagnosis and treatment. If this morbidity is to be reduced, a better understanding is needed of the factors which influence adjustment to cancer.MethodA review of the literature was carried out to explore those factors associated with poor psychological adjustment to cancer. These are described under four headings: characteristics of the patient; disease and treatment variables; the interaction between patient and illness; and environmental factors.ResultsA number of risk factors for psychiatric morbidity can be identified from each of the four areas. Methodological limitations are highlighted, in particular the preponderance of cross-sectional study designs.ConclusionsIncreased awareness of the risk factors for psychiatric morbidity should lead to earlier detection and more appropriate treatment. Future research should focus on those risk factors which are potentially modifiable.

Chilaiditi Syndrome and Recurrent Colonic Volvulus: A Case Report

2001 ◽  
Vol 87 (2) ◽  
pp. 111-112
Author(s):  
Jon Matthews ◽  
Giles W Beck ◽  
Douglas M G Bowley ◽  
Andrew N Kingsnorth
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Case Report ◽  
Optimal Treatment ◽  
X Ray ◽  
Colonic Volvulus ◽  
Chilaiditi’S Syndrome ◽  
Chest X Ray ◽  
Chilaiditi’S Sign ◽  
Chilaiditi's Syndrome

AbstractThe case of a 31 year old male presenting as an emergency with a recurrent colonic volvulus is described. A chest X-ray on admission to hospital showed the presence of hepato-diaphragmatic interposition of the colon, Chilaiditi’s Sign, which is known to be a risk factor for colonic volvulus. This is only the fourth reported case of colonic volvulus in association with Chilaiditi’s Syndrome and the first with recurrent colonic volvulus. The optimal treatment for recurrent volvulus in patients with risk factors such as Chilaiditi’s Syndrome or megacolon is also discussed.

scholarly journals Familial, Social and Environmental Risk Factors in Autism: A Case-Control Study

2015 ◽  
Vol 40 (3) ◽  
pp. 113-117 ◽  
Author(s):  
A Jahan ◽  
SZR Rezina Parvin ◽  
D Bugum
Keyword(s):  
Risk Factors ◽  
Environmental Risk ◽  
Case Control Study ◽  
Significant Proportion ◽  
Case Control ◽  
Delay Group ◽  
Environmental Risk Factors ◽  
Control Group ◽  
Autism Group ◽  
Control Study

This case-control study was done to identify the correlation between the familial, social and environmental risk factors and autism. This hospital and specialized centre based study done from January 2002 to November, 2004. Thirty two children from the autism group and 14 children from the control group were enrolled. Mean age were 3.75 yrs. and 2.83 yrs. respectively. Significant proportion of children were in the highest birth orders, 68.8% in autism and 78.6% in the control group. Full term children were 96.9% and 92.9% respectively. 53.1% children in the autism and 57.1% in the normal speech delay group were born by cesarean sections. Higher education of parents in autism group was statistically significant (p<0.05). Too much watching TV, inadequate opportunity to mix with peers and inadequate interactive relationship with the family members in the early childhood were significantly (p= 0.001) related to the development of autism.Bangladesh Med Res Counc Bull 2014; 40 (3): 113-117

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