scholarly journals Mitral Valve Prolapse In Patients With Benign Joint Hypermobility Syndrome (BJHS)

2019 ◽  
Vol 13 (1) ◽  
pp. 8-10
Author(s):  
Tariq Jassim Mohammed ◽  
Tariq Jassim Mohammed
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Prolapse ◽  
Cross Sectional Study ◽  
Joint Hypermobility ◽  
Control Group ◽  
Hypermobility Syndrome ◽  
Joint Hypermobility Syndrome ◽  
Chi Square ◽  
Cross Sectional ◽  
Cardiac Assessment

Background: Joint hypermobility  was first mentioned by Hippocrates as an isolated feature, when he described the Celts' Incapacity to Pull a Bowstring or Throw a Dart, Due to The Slackness of Their Limbs Objective: to determine the prevalence of mitral valve prolapse(MVP)in patients with benign hypermobility syndrome (BJHS). Type of the study: Cross –sectional study. Methods: Ninety patients with BJHS were included in this study. Full cardiological assessment was done for all of them,  which  include clinical examination, electrocardiography and echocardiography. Cardiac assessment was done for another sixty age and sex matched (normal mobile) Individuals served as a control group. Statistical analysis was done by using T test or chi square as indicated. Results: Among 90 patients with BJHS, MVP was reported in 26 patients (28.9%) compared to four individuals (6.7%)of the control group on modern echocardiography studies (P=0.013). Conclusions: the prevalence of MVP was significantly higher among patients with BJHS compared to normal mobile individuals.    

scholarly journals Role of heritable connective tissue diseases phenotypes in assessing the risk for internal diseases

2014 ◽  
Vol 95 (4) ◽  
pp. 501-505
Author(s):  
A V Tyurin ◽  
R A Davletshin ◽  
R M Muratova
Keyword(s):  
Mitral Valve ◽  
Connective Tissue ◽  
Mitral Valve Prolapse ◽  
Musculoskeletal Diseases ◽  
Connective Tissue Diseases ◽  
Joint Hypermobility ◽  
Hypermobility Syndrome ◽  
Joint Hypermobility Syndrome ◽  
Systemic Manifestations

Aim. To identify the prevalence of main phenotypes of polygenic heritable connective tissue diseases in patients with internal diseases and to assess the prevalence of different internal diseases in such patients. Methods. The study involved 600 patients (254 males, 346 females) aged 18 to 64 years. Average age of males was 52±3.8 years, females - 47±2.2 years. Patients were examined to reveal the signs of different phenotypes of heritable connective tissue diseases in patients with internal diseases, as well as the severity of connective tissue diseases, and possibilities for it screening using the wrist and thumb hypermobility tests. Results. Signs of heritable connective tissue diseases were revealed in 147 (24.5%) patients with internal diseases. In females, those signs were observed in 104 (30.0%) cases, of which 44 (42.3%) were graded as mild, 35 (33.7%) - moderate, 25 (24.0%) - severe. In males, signs of heritable connective tissue diseases were revealed in 43 cases (16.9%), including mild - 17 (39.5%), moderate - 14 (32.5%) and severe - 12 (28.0%). Ehlers-like phenotype was the most common (52.0%), Marfan-like phenotype was observed in 14.0% of cases, primary mitral valve prolapse was diagnosed in 7.0% of patients, unclassifiable phenotype was observed in 11.0% of cases. Joint hypermobility syndrome was revealed in 31.0% of patients, presenting both as specific phenotypes (Marfan-like, Ehlers-like) and as a self-phenotype (31.9% of all the patients with heritable connective tissue diseases phenotype). Benign joint hypermobility was observed in 6.1% of cases. Symptoms of heritable connective tissue diseases were more frequent in patients with gastrointestinal and musculoskeletal diseases. Conclusion. The most common phenotype of heritable connective tissue diseases is Ehlers-like with skin, bone and systemic manifestations. Presence of heritable connective tissue diseases was most commonly associated with gastrointestinal and musculoskeletal diseases.

P.3.034 Joint hypermobility syndrome in panic disorder patients with and without mitral valve prolapse

2003 ◽  
Vol 13 ◽  
pp. S367-S368
Author(s):  
D. Gulpek ◽  
E. Bayraktar ◽  
S. Pyryldar ◽  
K. Capacy ◽  
M. Kayykcyoglu ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Panic Disorder ◽  
Mitral Valve Prolapse ◽  
Joint Hypermobility ◽  
Hypermobility Syndrome ◽  
Joint Hypermobility Syndrome

Joint hypermobility syndrome and mitral valve prolapse in panic disorder

2004 ◽  
Vol 28 (6) ◽  
pp. 969-973 ◽  
Author(s):  
Demet Gulpek ◽  
Erhan Bayraktar ◽  
Sebnem Pirildar Akbay ◽  
Kazým Capaci ◽  
Meral Kayikcioglu ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Panic Disorder ◽  
Mitral Valve Prolapse ◽  
Joint Hypermobility ◽  
Hypermobility Syndrome ◽  
Joint Hypermobility Syndrome

scholarly journals ANALYSIS OF CERVICAL SAGITTAL PARAMETERS IN PATIENTS WITH RHEUMATOID ARTHRITIS

2021 ◽  
Vol 20 (2) ◽  
pp. 94-97
Author(s):  
Kaio Rodrigo Barreto Ramiro ◽  
Sylvio Mystro Neto ◽  
Ivan Guidolin Veiga ◽  
André Frazão Rosa ◽  
Mauricio Coelho Lima ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Sagittal Plane ◽  
Epidemiological Data ◽  
Cross Sectional Study ◽  
Control Group ◽  
Chi Square ◽  
Level Of Evidence ◽  
Cross Sectional ◽  
Thoracic Inlet ◽  
Sagittal Parameters

ABSTRACT Objective: To analyze the cervical sagittal parameters of patients with rheumatoid arthritis (RA) and compare them with the parameters obtained from healthy patients in a sample of the Brazilian population. Methods: Epidemiological data were collected and 72 radiographs of the cervical spine in the sagittal plane were evaluated by measuring the cervical sagittal parameters COG-C7 (distance measured between the center of gravity of the head and the C7 plumb line -cranial offset), C2-C7 lordosis (vertebrae from C2 to C7), T1S (T1 slope), TIA (thoracic inlet angle) and NT (neck tilt). Statistical analysis was performed using the Student’s t and chi-square tests. Results: The TIA and NT values in the RA group were 88.8° ± 12.6° and 54.5° ± 9.3°, respectively, while for the control group, they were 77.7° ± 7.9° and 50.5° ± 7.7°, respectively, the RA group values being statistically higher than the control group values (p <0.001 and p = 0.050, respectively). The values obtained for COG-C7, C2-C7 lordosis and T1S for the RA group were 9.4 ± 16.4mm, 25° ± 22.4° and 2.6° ± 10.1°, respectively, while for the control group they were 11.8 ± 17.6mm, 26.8° ± 12.5° and 30.9° ± 8.4°, respectively. Conclusions: Patients with RA present changes in the thoracic inlet parameters as compared to the control group, with a statistically significant increase in the TIA and NT values, outlining a characteristic compensatory pattern for maintaining cervical sagittal balance. Level of evidence III; Controlled cross-sectional study.

scholarly journals Exposure To Cytotoxic Drugs Threatens The Health Of Staff In Oncology Wards

2021 ◽  
Vol 10 (3) ◽  
Author(s):  
Mohsen Momeni ◽  
Mehrdad Askarian ◽  
Hossein Azad ◽  
Mina Danaei
Keyword(s):  
Demographic Data ◽  
Cross Sectional Study ◽  
Cytotoxic Drugs ◽  
Control Group ◽  
Chronic Complications ◽  
Chi Square ◽  
Cross Sectional ◽  
Staff Members ◽  
Runny Nose ◽  
Acute Complications

Background — Cancer is one of the leading causes of death worldwide. Using cytotoxic drugs for cancer treatment is increased. The hazardous effects of occupational exposure to cytotoxic drugs are challenging. Objective — This study aimed to compare the frequency of adverse effects and using personal protective equipment (PPE) between the staff of oncology wards and other hospital wards staff in Iran. Methods — A cross-sectional study with a control group was conducted on female staff members in educational hospitals, selected through convenience sampling. A data collection form was designed for this study. It includes demographic data, acute complications (allergic and neurologic reactions), chronic complications (infertility, menstrual disorders, malignancy, and congenital malformations), and use of PPE. Data analysis was performed using SPSS software through Chi-square and Mann-Whitney tests. Results — The frequencies of chronic complications were not statistically different between the two groups. The frequency of itching (P=0.001), hair loss (P=0.003), itchy eyes (P=0.001), watery eyes (P=0.001), runny nose (P=0.003), headache (P=0.001), vertigo (P=0.007), and nausea (P=0.008) were significantly higher in oncology wards nurses. Among different PPE, only the frequency of using the mask (P= 0.001), and glasses (P=0.027) were significantly higher in the staff of oncology wards. Conclusion — Despite the frequency of acute complications of exposure to cytotoxic drugs, oncology staff does not fully adhere to the standard precautions. Providing effective training and emphasis on implementing accreditation laws can improve the existing situation.

scholarly journals Specific Treatment Exists for SARS-CoV-2 ARDS

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 635
Author(s):  
Badar Kanwar ◽  
Chul Joong Lee ◽  
Jong-Hoon Lee
Keyword(s):  
Influenza Pandemic ◽  
Specific Treatment ◽  
Case Series ◽  
Cross Sectional Study ◽  
Control Group ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
High Death ◽  
1918 Influenza

The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), seems to be difficult to overcome. A pandemic of such a scale has not been seen since the 1918 influenza pandemic. Although the predominant clinical presentation is respiratory disease, neurological manifestations and sequelae are increasingly being recognized. We observed a case series of rapid recovery of ARDS within 24 h in the preliminary clinical features of COVID-19 ARDS-associated neurological disease. It was also noted that by 15 April, 2021, there was no SARS-CoV-2 ARDS on Sorok Island in South Korea, where lepers had been living together. We compared each of dapsone’s effects on humans and considered those of SARS-CoV-2. Dapsone showed different effects in the brain. The Sorokdo National Hospital reported a relationship between dapsone and the neuroinflammasome of Alzheimer’s disease (AD) in Sorok Island from January 2005 to June 2020. AD prevalence was low in the leprosy patient group who took dapsone regularly. The preliminary cross-sectional study of the trial group (22 subjects) and the control group (22 subjects) in the Hunt Regional Hospital reported the following results: The chi-square statistic is 5.1836. The p-value is 0.022801. The result is considered significant at p < 0.05. The results from the medical treatment from 21 December to 29 December 2020 were considered. The mortality rates at the ARDS onset stage were 0% with dapsone administered as a standard COVID-19 treatment and 40% without dapsone administered as a standard COVID-19 treatment, respectively. Based on the respiratory failure and sudden high death rate originating from the involvement of the brainstem, especially the pre-Bötzinger complex, dapsone can be used to significantly reduce the incidence of the cases of acute respiratory distress syndrome and other illnesses caused by SARS-CoV-2.

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