scholarly journals USING THE TECHNICAL EXPERIMENT IN THE COMPUTER SIMULATION TRAINING FOR PROSPECTING SOFTWARE ENGINEERS

2020 ◽  
pp. 216-223
Author(s):  
Maryna Litvinova ◽  
Oleg Dudchenko ◽  
Oleksandr Shtanko ◽  
Svitlana Karpova
Keyword(s):  
Computer Simulation ◽  
Comparative Analysis ◽  
Simulation Training ◽  
New Technology ◽  
The Body ◽  
Training Process ◽  
Software Developers ◽  
Software Engineers ◽  
Further Development ◽  
Modern Standard

In present work, a new technology of the prospective software engineers training in computer simulation is described. The technology provides carrying out comparative analysis of opportunities, productivity, and the accuracy of the reproduction of different computer simulation packages (CSP) on the basis of direct performance of the technical experiment results. Training process includes the principal stages: carrying out of the independent technical experiment; its simulation using of various CSP; comparison of the result of the tested CSP to the results of the experiment; models of debugging; detection of advantages and shortcomings of each involved CSP. As an example, in Open Modelica and Mathcad packages analysis of simulation opportunities of a problem of the motion of the body thrown at an angle to the horizon is carried out. As a result, assessment of the efficiency of each CSP used for the solution of an objective is made. When training prospective software developers the offered technology is the basis for further development of the modern standard in the field of computer simulation.

Gut microbiome a promising target for management of respiratory diseases

2020 ◽  
Vol 477 (14) ◽  
pp. 2679-2696
Author(s):  
Riddhi Trivedi ◽  
Kalyani Barve
Keyword(s):  
Respiratory Diseases ◽  
New Technology ◽  
Bacterial Flora ◽  
Systemic Circulation ◽  
The Body ◽  
Lung Pathology ◽  
Promising Target ◽  
Current Therapies ◽  
Intestinal Microbial Flora ◽  
On Chip

The intestinal microbial flora has risen to be one of the important etiological factors in the development of diseases like colorectal cancer, obesity, diabetes, inflammatory bowel disease, anxiety and Parkinson's. The emergence of the association between bacterial flora and lungs led to the discovery of the gut–lung axis. Dysbiosis of several species of colonic bacteria such as Firmicutes and Bacteroidetes and transfer of these bacteria from gut to lungs via lymphatic and systemic circulation are associated with several respiratory diseases such as lung cancer, asthma, tuberculosis, cystic fibrosis, etc. Current therapies for dysbiosis include use of probiotics, prebiotics and synbiotics to restore the balance between various species of beneficial bacteria. Various approaches like nanotechnology and microencapsulation have been explored to increase the permeability and viability of probiotics in the body. The need of the day is comprehensive study of mechanisms behind dysbiosis, translocation of microbiota from gut to lung through various channels and new technology for evaluating treatment to correct this dysbiosis which in turn can be used to manage various respiratory diseases. Microfluidics and organ on chip model are emerging technologies that can satisfy these needs. This review gives an overview of colonic commensals in lung pathology and novel systems that help in alleviating symptoms of lung diseases. We have also hypothesized new models to help in understanding bacterial pathways involved in the gut–lung axis as well as act as a futuristic approach in finding treatment of respiratory diseases caused by dysbiosis.

Osteopathic support of sportsmen during the annual training process

2020 ◽  
pp. 37-43 ◽  
Author(s):  
R. A. Yakupov ◽  
G. I. Safiullina ◽  
A. A. Safiullina ◽  
E. R. Burganov
Keyword(s):  
Musculoskeletal Diseases ◽  
Muscle Tone ◽  
The Body ◽  
Training Process ◽  
Health Maintenance ◽  
Osteopathic Treatment ◽  
Leading Position ◽  
Myofascial Syndrome ◽  
Sports Activities ◽  
Timely Treatment

Introduction. Modern sports places high demands on the functional systems of the body at all stages of the training and competitive processes. High loads create signifi cant background for the occurrence of musculoskeletal diseases, among which the myofascial syndrome (MFS) holds the leading position. MFS negatively affects the functional readiness of the sportsman′s body and is a risk factor for injuries of the musculoskeletal system. In this regard, timely treatment of MFS is important. It creates the conditions for the improvement of sports achievements, for health maintenance and sports longevity. Treatment of patients with MFS should include methods that normalize trophism and muscle tone. Given the problem of doping, the use of non-drug methods, including osteopathy, is preferable. The goal of research — to develop a system of monitoring and osteopathic correction of myofascial disorders (MFD) and to introduce it into the practice of medical and biological support for sportsmen of different categories and levels during the annual training process.Materials and methods. 93 sportsmen (45 women and 48 men), mean age 22,1±1,1 years, representing diffe rent sports were examined. The essence of the proposed system is regular clinical and electroneurophysiological monitoring of the body condition and preventive correction of myofascial disorders in order to exclude their infl uence on the success of sports activities.Results. It was established that the proposed system of monitoring and osteopathic correction led to a signifi cant reduction in clinical and electroneurophysiological manifestations both in local and in extensive forms of myofascial disorders, which allowed to maintain the optimal functional readiness of sportsmen throughout the entire annual training cycle.Conclusion. The system of monitoring and correction of MFS with the use of osteopathic treatment can be one of the elements of medical and biological support for sportsmen during the annual training process.

A Guide to Old Spanish

2018 ◽  
Author(s):  
Steven N. Dworkin
Keyword(s):  
The Body ◽  
Standard Language ◽  
Function Words ◽  
Sound System ◽  
Old Spanish ◽  
And Function ◽  
Linguistic Structures ◽  
Verb Tense ◽  
Modern Standard

This book describes the linguistic structures that constitute Medieval or Old Spanish as preserved in texts written prior to the beginning of the sixteenth century. It emphasizes those structures that contrast with the modern standard language. Chapter 1 presents methodological issues raised by the study of a language preserved only in written sources. Chapter 2 examines questions involved in reconstructing the sound system of Old Spanish before discussing relevant phonetic and phonological details. The chapter ends with an overview of Old Spanish spelling practices. Chapter 3 presents in some detail the nominal, verbal, and pronominal morphology of the language, with attention to regional variants. Chapter 4 describes selected syntactic structures, with emphasis on the noun phrase, verb phrase, object pronoun placement, subject-verb-object word order, verb tense, aspect, and mood. Chapter 5 begins with an extensive list of Old Spanish nouns, adjectives, verbs, and function words that have not survived into the modern standard language. It then presents examples of coexisting variants (doublets) and changes of meaning, and finishes with an overview of the creation of neologisms in the medieval language through derivational morphology (prefixation, suffixation, compounding). The book concludes with an anthology composed of three extracts from Spanish prose texts, one each from the thirteenth, fourteenth, and fifteenth centuries. The extracts contain footnotes that highlight relevant morphological, syntactic, and lexical features, with cross references to the relevant sections in the body of the book.

scholarly journals Dynamic Imaging of IEL-IEC Co-Cultures Allows for Quantification of CD103-Dependent T Cell Migration

2021 ◽  
Vol 22 (10) ◽  
pp. 5148
Author(s):  
Karin Enderle ◽  
Martin Dinkel ◽  
Eva-Maria Spath ◽  
Benjamin Schmid ◽  
Sebastian Zundler ◽  
...  
Keyword(s):  
T Cell ◽  
Cross Talk ◽  
Intestinal Inflammation ◽  
Ex Vivo ◽  
New Technology ◽  
Surface Expression ◽  
Intraepithelial Lymphocytes ◽  
Dynamic Imaging ◽  
The Body ◽  
Therapeutic Interventions

Intraepithelial lymphocytes (IEL) are widely distributed within the small intestinal epithelial cell (IEC) layer and represent one of the largest T cell pools of the body. While implicated in the pathogenesis of intestinal inflammation, detailed insight especially into the cellular cross-talk between IELs and IECs is largely missing in part due to lacking methodologies to monitor this interaction. To overcome this shortcoming, we employed and validated a murine IEL-IEC (organoids) ex vivo co-culture model system. Using livecell imaging we established a protocol to visualize and quantify the spatio-temporal migratory behavior of IELs within organoids over time. Applying this methodology, we found that IELs lacking CD103 (i.e., integrin alpha E, ITGAE) surface expression usually functioning as a retention receptor for IELs through binding to E-cadherin (CD324) expressing IECs displayed aberrant mobility and migration patterns. Specifically, CD103 deficiency affected the ability of IELs to migrate and reduced their speed during crawling within organoids. In summary, we report a new technology to monitor and quantitatively assess especially migratory characteristics of IELs communicating with IEC ex vivo. This approach is hence readily applicable to study the effects of targeted therapeutic interventions on IEL-IEC cross-talk.

Effects of Computer Simulation Training on In Vivo Discrete Trial Teaching

2012 ◽  
Vol 43 (3) ◽  
pp. 569-578 ◽  
Author(s):  
Sigmund Eldevik ◽  
Iwona Ondire ◽  
J. Carl Hughes ◽  
Corinna F. Grindle ◽  
Tom Randell ◽  
...  
Keyword(s):  
Computer Simulation ◽  
Simulation Training ◽  
Discrete Trial Teaching ◽  
Discrete Trial

Current trends in the development of isotonic drinks for athletes

2021 ◽  
pp. 311-317
Author(s):  
N.M. Podgornova ◽  
A.R. Zainutdinova
Keyword(s):  
Comparative Analysis ◽  
Fluid Balance ◽  
Consumer Preferences ◽  
The Body ◽  
Sucrose Content ◽  
Current Trends ◽  
High Sucrose

The article reflects the importance of isotonic drinks to maintain optimal fluid balance and replace the loss of electrolytes in the body of athletes. Consumer preferences are studied, and a comparative analysis of some isotonic drinks is presented. It has been established that the majority of isotonic agents have artificial colors, preservatives, and high sucrose content, the excessive use of which leads to the formation of various kinds of diseases.

Computer Simulation for Ergonomic Bus Operator Workstation Design With Validation

1998 ◽  
Author(s):  
H. You ◽  
B. Oesterling ◽  
B. Lowe ◽  
B. J. Gilmore ◽  
A. Freivalds
Keyword(s):  
Computer Simulation ◽  
The Body ◽  
Medium Size ◽  
Kinematic Constraints ◽  
Test Track ◽  
Human Models ◽  
Workstation Design ◽  
Body Joints ◽  
Bus Operator ◽  
Simulation Package

Abstract Bus operator’s workstations neglecting ergonomic features can cause overall discomfort and injuries to the users. This paper presents use of JACK®, a human work simulation package, in designing and evaluating a bus operator workstation which can provide sufficient visibility, natural reach, and comfortable posture for operators who range from the 5th percentile female to the 95th percentile male as defined by SAE J833 (SAE, 1994). Three human models representing the two extremes and their medium size person were created and performed 15 bus operating tasks on the bus workstation implemented in JACK®. Kinematic constraints were defined between the human models and the workstation to simulate the tasks in a realistic manner. While the human models simulated the tasks, the body joints were monitored to determine if they exceeded their comfort ranges recommended by Diffrient et al. (1981) and the workstation was evaluated in terms of visibility, reach, comfort, and adjustability. After the workstation design was refined by iterative modifications and the required component adjustment ranges were determined, the workstation design was prototyped into an actual working bus. A jury of bus operators evaluated the workstation design by operating the prototype on a test track. The response from the operators indicated that the workstation would accommodate the intended population.

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