scholarly journals Efficacy of Lignocaine in Gel and Spray form during Buccal Infiltration Anesthesia in Children: A Randomized Clinical Trial

2014 ◽  
Vol 15 (6) ◽  
pp. 750-754 ◽  
Author(s):  
Anshul Sharma ◽  
BS Suprabha
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Rating Scale ◽  
Permanent Teeth ◽  
Chi Square ◽  
Topical Anesthetic ◽  
Significant Difference ◽  
Spray Form ◽  
Buccal Infiltration ◽  
Infiltration Anesthesia

ABSTRACT Aim To compare the efficacy of 15% lignocaine spray and 8% lignocaine gel as a topical anesthetic, in reducing pain, during buccal infiltration in children. Materials and methods Forty-two patients aged between 7 and 12 years requiring restorative procedures/extraction/pulp therapy of primary/ permanent teeth in the maxillary arch, under buccal infiltration anesthesia were selected for the study. The participants were randomly allocated into 2 groups of 21 each. In group A, 8% lignocaine gel and in group B, 15% lignocaine spray was applied prior to buccal infiltration. Pain was assessed using Wong-Baker faces pain rating scale (WBFPRS) and faces legs activity cry and consolability (FLACC) painscale. Results Pearson's chi-square test revealed that there was no significant difference in the FLACC scores of the two groups (p = 0.54). Independent t-test demonstrated that there was no significant difference in Wong-Bakers faces pain score between the two agents (p = 0.07). Conclusion There is no significant difference in the efficacy of 15% lignocaine spray and 8% lignocaine gel as a topical anesthetic in controlling pain during buccal infiltration anesthesia, in children. How to cite this article Sharma A, Suprabha BS, Shenoy R, Rao A. Efficacy of Lignocaine in Gel and Spray form during Buccal Infiltration Anesthesia in Children: A Randomized Clinical Trial. J Contemp Dent Pract 2014;15(6):750-754.

Dance Rhythms Improve Motor Symptoms in Individuals with Parkinson’s Disease: A Randomized Clinical Trial

2021 ◽  
Author(s):  
Jéssica A. Moratelli ◽  
Kettlyn H. Alexandre ◽  
Leonessa Boing ◽  
Alessandra Swarowsky ◽  
Clynton L. Corrêa ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Clinical Trial ◽  
Parkinson's Disease ◽  
Randomized Clinical Trial ◽  
Rating Scale ◽  
Freezing Of Gait ◽  
Motor Symptoms ◽  
Score Change ◽  
Significant Difference ◽  
Binary Group

Background: Evidence-based practices involving dance modalities found in binary (two-beat rhythm) or quaternary (four-beat rhythm) show that dance positively influences the motor aspects of disease.Aim: This randomized clinical trial aimed to analyze the effect of two dance rhythm (binary and quaternary) on the balance, gait, and mobility in individuals with Parkinson’s disease (PD). Methods: Thirty-one individuals with PD were randomized into the binary group (n = 18) and the quaternary group (n = 13). Both groups participated in different dance rhythms lasting 12 weeks, twice a week, for 45 minutes. Results: The binary group showed a significant difference in balance (p = 0.003), freezing of gait (p = 0.007), as well as in the motor aspects of MDS-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS), with emphasis on the total values with a score change of 3.23. In the quaternary group, significant differences were found in balance (p = 0.021) with a score change of -2.54 and in the motor aspects of the MDS-UPDRS Part III where the total values stood out with a change of 3.54. Discussion: When comparing the possible effects of binary and quaternary rhythms on the motor symptoms of individuals with PD, it was demonstrated that binary rhythm improved balance, freezing gait, and UPDRSIII. As for the quaternary rhythm, the benefits were in balance and the UPDRSIII. Conclusion: The binary and the quaternary rhythm dance protocols positively influenced the motor symptoms of individuals with PD after 12 weeks of intervention.

scholarly journals Intravenous Paracetamol vs Intranasal Desmopressin for Renal Colic in the Emergency Department: A Randomized Clinical Trial

Pain Medicine ◽  
2020 ◽  
Vol 21 (12) ◽  
pp. 3437-3442
Author(s):  
Hamed Basir Ghafouri ◽  
Niloofar Abazarian ◽  
Mohammadreza Yasinzadeh ◽  
Ehsan Modirian
Keyword(s):  
Clinical Trial ◽  
Emergency Department ◽  
Pain Score ◽  
Randomized Clinical Trial ◽  
Renal Colic ◽  
Rating Scale ◽  
Pain Scores ◽  
Intravenous Paracetamol ◽  
Significant Difference ◽  
Intranasal Desmopressin

Abstract Objective To evaluate the analgesic efficacy of intranasal desmopressin alone vs intravenous paracetamol in patients referred to the emergency department with renal colic. Design Randomized clinical trial. Setting This study was conducted in the emergency unit of a university hospital. Subjects Patients referred to the emergency room with renal colic. Primary Outcome Effect of intranasal desmopressin in pain relief in comparison with intravenous paracetamol. Methods In this trial, 240 patients diagnosed with renal colic were randomly divided into two groups to compare the analgesic effect of intravenous paracetamol (15 mg/kg) and intranasal desmopressin spray (40 μg). Pain scores were measured by a numeric rating scale at baseline and after 15, 30, and 60 minutes. Adverse effects and need for rescue analgesic (0.05 mg/kg max 3 mg morphine sulphate) were also recorded at the end of the study. Results Three hundred patients were eligible for the study; however, 240 were included in the final analysis. The patients in the two groups were similar in their baseline characteristics and baseline pain scores. The mean pain score after 15 minutes was more reduced and was clinically significant (>3) in the desmopressin group (P < 0.0001). There was no significant difference between mean pain scores in the two groups after 30 minutes (P = 0.350) or 60 minutes (P = 0.269), but the efficacy of the two drugs was significant in terms of pain reduction (>6). Conclusions Our study showed that intranasal desmopressin is as effective as intravenous paracetamol for renal colic pain management; however, significant clinical reduction in pain score occurred faster with intranasal desmopressin.

scholarly journals Coadministration of ibuprofen/caffeine on bleaching-induced tooth sensitivity: A randomized clinical trial

2021 ◽  
Vol 32 (3) ◽  
pp. 105-115
Author(s):  
Karine Letícia da Silva ◽  
Elisama Sutil ◽  
Diego Hortkoff ◽  
Renata Maria Oleniki Terra ◽  
Márcia Rezende ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Repeated Measures ◽  
Rating Scale ◽  
Absolute Risk ◽  
Tooth Sensitivity ◽  
Dental Bleaching ◽  
Significance Level ◽  
Significant Difference ◽  
The Absolute

Abstract This clinical trial evaluated the effect of the coadministration of ibuprofen/caffeine on bleaching-induced tooth sensitivity (TS). A triple-blind, parallel-design, randomized clinical trial was conducted on 84 patients who received ibuprofen/caffeine or placebo capsules. The drugs were administered for 48 hours, starting 1 hour before the in-office bleaching. Two bleaching sessions were performed with 35% hydrogen peroxide gel with 1-week interval. TS was recorded up to 48 hours after dental bleaching with a 0-10 visual analogic scale (VAS) and a 5-point numeric rating scale (NRS). The color was evaluated with VITA Classical and VITA Bleachedguide scales (ΔSGU) and VITA Easyshade spectrophotometer (ΔE*ab and ΔE00). The absolute risk of TS in both groups was evaluated using Fischer's exact test. Comparisons of the TS intensity (NRS and VAS data) were performed by using the Mann-Whitney test and a two-way repeated measures ANOVA, respectively. The color alteration between the groups was compared with the Student's t test. The significance level was 5%. There was no statistically significant difference between the groups for the absolute risk of TS (p = 1.00) or for the intensity of TS (p > 0.05). A bleaching of approximately 7 shade guide units was observed on the Vita Classical and Vita Bleachedguide scales, with no statistical difference between the groups. It was concluded that coadministration of ibuprofen and caffeine did not reduce the absolute risk or intensity of TS and did not interfere with the efficacy of dental bleaching.

scholarly journals Effect of Nitrous Oxide on Pulpal Anesthesia: A Preliminary Study

2018 ◽  
Vol 65 (3) ◽  
pp. 156-161
Author(s):  
Papimon Chompu-inwai ◽  
Sophon Simprasert ◽  
Patchanee Chuveera ◽  
Areerat Nirunsittirat ◽  
Thanapat Sastraruji ◽  
...  
Keyword(s):  
Nitrous Oxide ◽  
Rating Scale ◽  
Permanent Teeth ◽  
Chi Square ◽  
Significant Difference ◽  
Nitrous Oxide Oxygen ◽  
Chi Square Test ◽  
Preliminary Study ◽  
Pulpal Anesthesia ◽  
Irreversible Pulpitis

To compare the success of perceived pulpal anesthesia between groups using nitrous oxide/oxygen (N2O/O2) and oxygen (O2) in children premedicated with ibuprofen with symptomatic irreversible pulpitis permanent teeth. Thirty-three children (mean age 10.4 ± 1.9 years) with 33 symptomatic irreversible pulpitis permanent teeth were included in this preliminary study. All children were premedicated with ibuprofen and randomly assigned to receive either N2O/O2 (17 participants) or O2 (16 participants). Four percent articaine with epinephrine 1:100,000 was administered, and vital pulp therapy was performed. Children used the Wong-Baker FACES Pain Rating Scale (WBFPS) to report their pain at baseline as well as during carious dentin removal, pulpal exposure, and pulpal tissue removal steps. The success was determined when the reported WBFPS score was ≤4. The chi-square test was used to compare the success between both groups. The success of pulpal anesthesia was 71% (12/17) and 19% (3/16) in the N2O/O2 and O2 groups, respectively. The success in the N2O/O2 group was 52% higher than that in the O2 group (confidence interval = 22.9% to 80.7%; significant difference p = .003). From the result of this preliminary study, N2O/O2 significantly increased the success of perceived pulpal anesthesia in children premedicated with ibuprofen with symptomatic irreversible pulpitis permanent teeth. However, further study with a larger sample is required to confirm this result.

scholarly journals The degree of color change, rebound effect and sensitivity of bleached teeth associated with at-home and power bleaching techniques: A randomized clinical trial

2013 ◽  
Vol 07 (04) ◽  
pp. 405-411 ◽  
Author(s):  
Fatemeh Velayati Moghadam ◽  
Sara Majidinia ◽  
Joseph Chasteen ◽  
Marjaneh Ghavamnasiri
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Color Change ◽  
Rebound Effect ◽  
Color Difference ◽  
Chi Square ◽  
Tooth Color ◽  
Anterior Teeth ◽  
Significant Difference ◽  
At Home

ABSTRACT Aim: The purpose of the present randomized clinical trial was to evaluate the color change, rebound effect and sensitivity of at-home bleaching with 15% carbamide peroxide and power bleaching using 38% hydrogen peroxide. Materials and Methods: For bleaching techniques, 20 subjects were randomized in a split mouth design (at-home and power bleaching): In maxillary and mandibular anterior teeth (n = 20). Color was recorded before bleaching, immediately after bleaching, at 2 weeks, 1, 3 and 6 month intervals. Tooth sensitivity was recorded using the visual analog scale. The Mann-Whitney test was used to compare both groups regarding bleaching effectiveness (∆E 1 ), rebound effect (∆E 2 ) and color difference between the rebounded tooth color and unbleached teeth (∆E 3) while the Wilcoxon compared ∆E within each group. Distribution of sensitivity was evaluated using the Chi-square test (α =0.05). Results: There was no significant difference between groups regarding ∆E 1 and ∆E 3 (P > 0.05). Even though, ∆E 2 showed no significant difference between groups after bleaching as well as at 2 week, 1 month and 3 month follow-up periods (P > 0.05). Although, significant difference was found in ∆E 2 (P < 0.05 Mann-Whitney) between two methods after 6 months and a high degree of rebound effect was obtained with power bleaching. Within each group, there was no significant difference between ∆E 1 and ∆E 3 (P < 0.05 Wilcoxon). The distribution of sensitivity was identical with both techniques (P > 0.05).Conclusion: Bleaching techniques resulted in identical tooth whitening and post-operative sensitivity using both techniques, but faster color regression was found with power bleaching even though color regression to the baseline of the teeth in both groups was the same after 6 months.

scholarly journals Postoperative pain of patients with necrotic teeth with apical periodontitis following single visit endodontic treatment versus multiple visit endodontic treatment using triple antibiotic paste: a randomized clinical trial

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 1203
Author(s):  
Safeya AbdurRahman ◽  
Saied M. Abdel Aziz ◽  
Shaimaa I. Gawdat ◽  
Ahmed M. AbdalSamad
Keyword(s):  
Clinical Trial ◽  
Postoperative Pain ◽  
Randomized Clinical Trial ◽  
Rating Scale ◽  
Apical Periodontitis ◽  
Endodontic Treatment ◽  
Single Visit ◽  
Triple Antibiotic Paste ◽  
Multiple Visit ◽  
Significant Difference

Background: A randomized clinical trial was conducted to compare the postoperative pain following endodontic treatment of necrotic teeth with apical periodontitis. Treatments were performed in multiple visits with application of triple antibiotic paste interappointment dressing or single visit without interappointment dressing. Methods: In total 44 participants were assigned randomly into two groups. Group A: multiple visit endodontic treatment with triple antibiotic paste interappointment dressing; group B: single visit endodontic treatment without interappointment dressing. Postoperative pain of participants was assessed after 24, 48, 72 hours and one week using numerical rating scale. Results: No statistically significant difference was found in postoperative pain after 24, 48, 72 hours and one week between the two groups. Conclusion: Triple antibiotic paste as an interappointment dressing in multiple visits endodontic treatment was not proved to reduce the postoperative pain compared to a single visit in patients with necrotic teeth with apical periodontitis who did not have an interappointment dressing. Trial registration: clinicaltrials.gov, NCT02947763. Date: 28th October 2016.

scholarly journals The Effect of Valerian and Ginger on Dysmenorrhea: A Randomized Clinical Trial

2018 ◽  
Vol 8 (1) ◽  
pp. 101-105
Author(s):  
Masoumeh Davood Abadi ◽  
Katayon Vakilian ◽  
Nafiseh Seyyed Zadeh Aghdam ◽  
Mehdi Ranjbaran
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Chi Square ◽  
Significance Level ◽  
Young Females ◽  
Analgesic Effects ◽  
Significant Difference ◽  
The Mean ◽  
And Control ◽  
Analgesic Use

Objectives: Dysmenorrhea is a frequent complaint in young females. In recent years, researchers have grown an interest in the use of herbal drugs to decrease menstrual pain given the side effects of chemical drugs. This project was conducted to evaluate the effect of valerian and ginger on the duration of pain and analgesic use in dysmenorrhea. Materials and Methods: This triple-blind randomized clinical trial was performed on 210 dormitory females who were randomly divided into valerian, ginger, and control groups after opening an envelope. In this study, 250 and 350 mg of ginger and valerian in each capsule were administered, respectively, and 250 mg sugar was used as a placebo. The number of days with pain and analgesic use were evaluated as well. Finally, descriptive (percentage and mean) and inferential (t test, post hoc, and chi-square at a significance level of 0.05) statistics were used to analyze the data. Results: The results of the study showed a marginally significant difference in the duration of pain between ginger (1.61±0.64 days) and control (2.12±0.81 days) groups (P=0.052), and significant difference between ginger (1.61±0.64 days) and valerian (2.53±1.43 days) groups (P=0.001). The mean days of analgesic use among the three groups were not different significantly (P>0.05). However, the mean severity of symptoms significantly differed between ginger (0.73±0.28) and control (0.3±0.04) groups and increased in the ginger group (P=0.003). Conclusions: In general, the administration of valerian and ginger at the doses used in this study failed to produce desirable analgesic effects and thus could not decrease the symptoms associated with dysmenorrhea

scholarly journals Tooth alignment and pain experience with A-NiTi versus Cu-NiTi: a randomized clinical trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fatemeh Azizi ◽  
Aida Extiari ◽  
Mohammad Moslem Imani
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Orthodontic Treatment ◽  
Pain Perception ◽  
Mcgill Pain Questionnaire ◽  
Dental Arch ◽  
Chi Square ◽  
Irregularity Index ◽  
Significant Difference ◽  
The Difference

Abstract Background Nickel-titanium (NiTi) archwires are routinely used for initial leveling and alignment of teeth in orthodontic treatment. This study aimed to clinically compare the level of pain and tooth alignment in orthodontic treatment with A-NiTi versus Cu-NiTi archwires. Methods In this parallel randomized clinical trial, 88 orthodontic patients (12–25 years) with an irregularity index > 2 mm in the anterior site of the lower dental arch who required non-extraction orthodontic treatment of the lower arch were randomized into two age- and sex-matched groups (n = 44) for treatment with A-NiTi and Cu-NiTi initial archwires. Each archwire was used for 6 weeks. After 6 weeks, the irregularity index was measured, and the level of pain was scored using the Modified McGill pain questionnaire (MPQ) and visual analog scale (VAS) according to the time of onset and duration of pain, and analgesic intake. Data were analyzed by paired t test, independent samples t test, and Chi-square test (P < 0.05). Results The irregularity index significantly decreased in both groups after 6 weeks of treatment (P < 0.001). However, the difference in this respect was not significant between the two groups (P > 0.05). Pain perception (P = 0.487), duration of pain (P = 0.546), and analgesic intake (P = 0.102) were not significantly different between the two groups either. Conclusion Both A-NiTi and Cu-NiTi archwires are equally effective for tooth alignment in the anterior site of the lower dental arch and have no significant difference with regard to the level of pain experienced by patients. Trial registration number: IRCT20190705044102N1 and Name of the registry: Iranian registry of clinical trials (https://irct.ir/) Date of registration: September, 26, 2019

Comparative Evaluation of Indirect Pulp Therapy in Young Permanent Teeth using Biodentine and Theracal: A Randomized Clinical Trial

2021 ◽  
Vol 45 (3) ◽  
pp. 158-164
Author(s):  
Bushra Rahman ◽  
Mousumi Goswami
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Permanent Teeth ◽  
Healthy Children ◽  
Chi Square ◽  
Significance Level ◽  
Pulp Therapy ◽  
Chi Square Test ◽  
Permanent Molars

Objective: In a tooth with deep dentinal caries; judicious removal of infected dentin and isolating affected dentin from oral fluids with suitable biocompatible material is called indirect pulp therapy (IPT). This randomized clinical trial was done to evaluate and compare the efficacy of Biodentine, Theracal LC and. Dycal as an indirect pulp capping agent in young permanent teeth. Study Design: IPT was performed in 60 young permanent molars with caries approaching pulp in 55 healthy children using Biodentine, Theracal and Dycal. A 2–3mm layer of GIC was placed over the intervening material followed by restoration of cavity with composite. Clinical and radiographic examinations were conducted at 3 weeks, 3 months, 6 months,12 months, 18 months and 24 months. The data was compared using chi-square test at a significance level of 0.05. Results: By end of 24 months ,54 teeth presented for follow up with overall success rate of 100% in Theracal, 94.44% in Biodentine, and 77.78% in Dycal. Overall success of Theracal was statistically significant in comparison to Biodentine and Dycal at 24 months follow up (p= 0.03) Conclusions: Radiographic and clinical outcomes of Theracal and Biodentine suggest their use as an alternative material for IPT in young permanent molars with higher success.

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