scholarly journals EVALUATION OF PERIPAPILLARY RETINAL NERVE FIBRE LAYER AND CENTRAL MACULAR THICKNESS INADULTS WITH HYPEROPIC ANISOMETROPIC AMBLYOPIA

2021 ◽  
Vol 71 (1) ◽  
pp. 162-66
Author(s):  
Tanveer Ahmed ◽  
Khizar Niazi ◽  
Sobia Usman Shah ◽  
Junaid Afsar Khan ◽  
Husnain Muhmmad Bukhsh ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Nerve Fibre ◽  
Statistical Significance ◽  
Retinal Nerve Fibre Layer ◽  
Macular Thickness ◽  
Central Macular Thickness ◽  
Anisometropic Amblyopia ◽  
Fibre Layer ◽  
The Mean ◽  
Nerve Fibre Layer

Objective: To study per-papillary retinal nerve fibre layer (pRNFL) and central macular thickness (CMT) changesin adults with hyperopic anisometropic amblyopia using optical coherence tomography. Study Design: Cross sectional study. Place and Duration of Study: Combined Military Hospital, Lahore, Pakistan, from Oct 2019 to Feb 2020. Methodology: In this study 30 adults, 18-40 years of age were included who presented in our clinic with monocular poor vision. They underwent detailed ophthalmic clinical examination: including corrected and uncorrected distance visual acuity, slit lamp bio-microscopy and fundus examination with 90 diopter lens. After fulfilling criteria of anisometropic amblyopia, central maular thickness (CMT) and per-papillary retinal nerve fibre layer (pRNFL) thickness was measured by using RS-3000 SLO, NIDEK Co, Japan spectral domain optical coherence tomography device and compared the central maular thickness (CMT) and per-papillary retinal nerve fibre layer (pRNFL) thickness in amblyopic and fellow eye of same individual. Results: The mean change in per-papillary retinal nerve fibre layer (pRNFL) thickness in amblyopic eyes, 121.48± 4.90 μm and non amblyopic eyes was 112.92 ± 4.72 μm with statistical significance (p<0.001). The mean change in central macular thickness (CMT) in amblyopic eyes was 198.50 ± 5.30 μm and non amblyopic eyes was 206.80 ± 3.11 μm with statistical significance (p<0.001). There was significant increase in per-papillary retinal nerve fibre layer (pRNFL) thickness and significant decrease in central macular thickness (CMT) on comparing the amblyopic and the fellow eyes of the same patients. Conclusion: Central macular thickness (CMT) decreased.........................

scholarly journals Retinal Nerve Fibre Layer and Macular Thicknesses in Adults with Hyperopic Anisometropic Amblyopia

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Konuralp Yakar ◽  
Emrah Kan ◽  
Aydın Alan ◽  
Mehmet Hanifi Alp ◽  
Tolga Ceylan
Keyword(s):  
Nerve Fibre ◽  
Retinal Nerve Fibre Layer ◽  
Macular Thickness ◽  
Cross Sectional ◽  
Anisometropic Amblyopia ◽  
Fibre Layer ◽  
Disc Area ◽  
The Mean ◽  
Nerve Fibre Layer ◽  
Fellow Eyes

Objectives. This study compared the macular and retinal nerve fibre layer (RNFL) thicknesses and optic nerves of eyes with reduced vision due to anisometropia with the contralateral healthy eyes in adults using optical coherence tomography (OCT).Methods. This cross-sectional study was conducted in Atatürk State Hospital, Sinop, Turkey. Macular and RNFL thicknesses, optic nerve disc area, cup area, and horizontal and vertical cup-to-disc ratios obtained using a NIDEK RS-3000 SLO spectral domain OCT device were compared between the amblyopic and fellow eyes in 30 adults with anisometropic amblyopia 18–55 years old who were seen in our clinic with unilateral poor vision.Results. The mean macular thickness was 266.90 ± 23.22 µm in the amblyopic eyes and 263.90 ± 22.84 µm in the fellow eyes, and the mean RNFL thickness was 111.90 ± 12.9 and 109.70 ± 9.42 µm, respectively. The two thicknesses did not differ significantly between the amblyopic and fellow eyes. There were also no significant differences between the eyes in disc area, cup area, and horizontal-vertical cup/disc ratios.Conclusion. There does not seem to be a difference in macular thickness, peripapillary RNFL, or optic disc structures between the amblyopic and fellow eyes in adults.

scholarly journals Central Macular Thickness in Children with Myopia, Emmetropia, and Hyperopia: An Optical Coherence Tomography Study

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Gordon S. K. Yau ◽  
Jacky W. Y. Lee ◽  
Tiffany T. Y. Woo ◽  
Raymond L. M. Wong ◽  
Ian Y. H. Wong
Keyword(s):  
Optical Coherence Tomography ◽  
Axial Length ◽  
Retinal Nerve Fibre Layer ◽  
Macular Thickness ◽  
Chinese Children ◽  
Central Macular Thickness ◽  
Optical Coherence ◽  
The Mean ◽  
Nerve Fibre Layer ◽  
Chinese Subjects

Purpose.To investigate the central macular thickness (CMT) in myopic, emmetropic, and hyperopic Chinese children using Optical Coherence Tomography.Methods.168 right eyes of Chinese subjects aged 4–18 were divided into 3 groups based on their postcycloplegic spherical equivalent: myopes (<−1.0 D); emmetropes (≥−1.0 to ≤+1.0 D); and hyperopes (>+1.0 D) and the CMT was compared before/after age adjustment. The CMT was correlated with age, axial length, and peripapillary retinal nerve fibre layer (RNFL).Results.The mean CMT was274.9±50.3 μm and the mean population age was7.6±3.3years. The CMT was thickest in the myopes (283.3±57.3 μm,n=56), followed by the hyperopes (266.2±55.31 μm,n=60) and then emmetropes (259.8±28.7 μm,n=52) (allP<0.0001). When adjusted for age, myopes had a thicker CMT than the other 2 groups (allP<0.0001) but there was no CMT difference between the emmetropes and hyperopes (P>0.05). There was no significant correlation between CMT with age, axial length, or peripapillary RNFL (allP≥0.2).Conclusion.Chinese children with myopia had a thicker CMT than those with emmetropia or hyperopia. There was no correlation of the CMT with age, axial length, or peripapillary RNFL thickness.

The volume of peripapillary vessels within the retinal nerve fibre layer: an optical coherence tomography angiography study of normal subjects

2017 ◽  
Vol 102 (5) ◽  
pp. 611-621 ◽  
Author(s):  
Davide Allegrini ◽  
Giovanni Montesano ◽  
Paolo Fogagnolo ◽  
Alfredo Pece ◽  
Roberta Riva ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Nerve Fibre ◽  
Optical Coherence Tomography Angiography ◽  
Vascular Tissue ◽  
Retinal Nerve Fibre Layer ◽  
Optical Coherence ◽  
Rnfl Thickness ◽  
Fibre Layer ◽  
The Mean ◽  
Nerve Fibre Layer

Background/aimsTo investigate the contribution of vascular volume calculated by optical coherence tomography angiography (OCTA) to the measurement of peripapillary retinal nerve fibre layer (RNFL) thickness.MethodsWe used OCTA scans to build volumetric maps of the RNFL angiograms by thresholding the decorrelation images and summing the number of white pixels along the z-axis at each location. We used these maps to calculate the contribution of the vascular tissue to the RNFL thickness.ResultsWe analysed 51 eyes from 36 subjects. The mean RNFL volume calculated on the peripapillary region was 0.607±0.045 mm3 and the mean vessel volume was 0.217±0.035 mm3, with a mean vessel/total RNFL ratio of 35.627%±3.942%. When evaluated in the peripapillary circular section, the total contribution of the vascular tissue to the global RNFL thickness was 29.071%±3.945%. The superior and inferior sectors showed the highest percentage of vascular tissue within the RNFL circular profile (31.369% and 34.788% respectively).ConclusionsWe found that the vascular contribution to the RNFL thickness is 29.07±3.945%. This is much higher than what has been reported from calculations made on the structural OCT alone (13% reported by Hood et al and 11.3%±1.6% for the Cirrus OCT and 11.8%±1.4% for the Spectralis OCT reported by Patel et al). We conclude that evaluation of the vascular tissue contribution to the RNFL thickness with OCTA might be useful when performing precise quantification of the neuronal tissue.

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