scholarly journals PHYTOCONSTITUENTS FROM THE ROOTS OF CUSCUTA CHINENSIS

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Srinivasarao Pendy ◽  
Sunitha Katta ◽  
Ganapaty Seru ◽  
Krishna Nallamothu
Keyword(s):  
Traditional Medicine ◽  
Betulinic Acid ◽  
Chemical Components ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Volatile Constituents ◽  
Whole Plant ◽  
Cuscuta Chinensis ◽  
First Time

Cuscuta chinensis, a parasitic vine, was used in several traditional medicine systems, and it demonstrated a wider range of pharmacological activities in various diseases. The chemical components from C. chinensis consist mainly of flavonoids, steroids, volatile constituents, lignans, alkaloids, and polysaccharides. In view of its wider pharmacological properties, the authors have attempted to re-investigate the whole plant for its phytoconstituents and reported flavones salvigenin, chrisimaritin for the first time apart from the earlier reported quercetin and triterpenoid betulinic acid.

Medicinal Inula Species: Phytochemistry, Biosynthesis, and Bioactivities

2021 ◽  
pp. 1-44
Author(s):  
Cheng-Peng Sun ◽  
Zi-Li Jia ◽  
Xiao-Kui Huo ◽  
Xiang-Ge Tian ◽  
Lei Feng ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Drug Development ◽  
Scientific Basis ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
The World ◽  
Phytochemical Constituents ◽  
New Drug Development ◽  
First Time

As a genus of the Asteraceae, Inula is widely distributed all over the world, and several of them are being used in traditional medicines. A number of metabolites were isolated from Inula species, and some of these have shown to possess ranges of pharmacological activities. The genus Inula contains abundant sesquiterpenoids, such as eudesmanes, xanthanes, and sesquiterpenoid dimers and trimers. In addition, other types of terpenoids, flavonoids, and lignins also exist in the genus Inula. Since 2010, more than 300 new secondary metabolites, including several known natural products that were isolated for the first time from the genus Inula. Most of them exhibited potential bioactivities in various diseases. The review aimed to summarize the advance of recent researches (2010–2020) on phytochemical constituents, biosynthesis, and pharmacological properties of the genus Inula for providing a scientific basis and supporting its application and exploitation for new drug development.

scholarly journals Phytochemistry, Traditional Uses and Pharmacological Properties of the Genus Opopanax W. D. J. Koch: A Mini-Review

2020 ◽  
Vol 26 (2) ◽  
pp. 99-106
Author(s):  
Alev Önder ◽  
Lutfun Nahar ◽  
Sushmita Nath ◽  
Satyajit D. Sarker
Keyword(s):  
Traditional Medicine ◽  
Mediterranean Region ◽  
Antimicrobial Activities ◽  
Evidence Based ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
Phytochemical Profile ◽  
The Mediterranean ◽  
Antioxidant And Antimicrobial Activities

The genus Opopanax W.D.J. Koch is a member of the Apiaceae family, distributed throughout the Mediterranean region and comprises only three recognized and well-defined species, O. chironium (L.) W.D.J. Koch, O. hispidus (Friv.) Griseb. and O. persicus Boiss. The species of this genus with yellow flowers are well-known in traditional medicine and consumed as food. This review critically appraises published literature on the phytochemistry, traditional usages, and pharmacological activities of the genus Opopanax. In addition, it provides evidence to suggest that the plants from this genus have potential phytotherapeutic applications. Previous phytochemical and bioactivity studies revealed that the genus Opopanax predominantly produces coumarins, diterpenes, phenolics, and phthalides, and possesses various biological and pharmacological properties, including anticancer, antioxidant and antimicrobial activities. The phytochemical profile and pharmacological activities of the genus Opopanax could be useful for further study and might find additional medicinal applications in evidence-based phytotherapy

scholarly journals A perspective review of phytochemistry and pharmacology of the Syzygium genus

2021 ◽  
Vol 12 (2) ◽  
pp. 1490-1495
Author(s):  
Yuniarni U ◽  
Sukandar E Y ◽  
Fidrianny I
Keyword(s):  
Traditional Medicine ◽  
Pharmacological Activity ◽  
Therapeutic Potential ◽  
Biological Activities ◽  
Ornamental Plants ◽  
Chemical Compounds ◽  
Chemical Components ◽  
Pharmacological Activities ◽  
Widespread Species ◽  
Traditional Uses

Syzygium is a genus of the Myrtaceae family consisting of large and widespread species from Africa, Asia, Australia, and throughout Oceania and the Pacific region. Some have been cultivated for bearing fruit, ornamental plants and used as traditional medicine. This article excavated Syzygium genus which was focused on traditional uses, chemical compounds and biological activities related to treatment of syndrome metabolic. All information was obtained from the scientific literature such as Science Direct, Google Scholar, Scopus and PubMed. Several species were known to have therapeutic potential and used in traditional Chinese medicine, Ayurveda, and herbal medicine in Indonesia. Traditionally, Syzygium is known for its therapeutic purposes such as coughing, diarrhea, colds, dysentery, inflammation, pain, skin, and mouth infections. Only a few species have been scientifically studied to verify their usage as traditional medicine. There were many reports on the traditional uses and medicinal effects of Syzygium plants, but only a few review articles mainly about phytochemical constituents and their role in pharmacological activities. The present reviews highlight the phytochemical and pharmacological activity of various species of the Syzygium genus. The pharmacological activities were discussed in this article focused to metabolic syndrome treatment, such as antidiabetic, antihyperlipidemic, antioxidant and antihypertensive activities. Chemical components isolated mainly flavonoid, terpenoids/sesquiterpenoid, sterols, and lignan. Several bioactive compounds have been identified correlated with pharmacological activity, but the chemical compounds were different for each species.

scholarly journals A Review of Botanical Characteristics, Traditional Usage, Chemical Components, Pharmacological Activities, and Safety ofPereskia bleo(Kunth) DC

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Sogand Zareisedehizadeh ◽  
Chay-Hoon Tan ◽  
Hwee-Ling Koh
Keyword(s):  
Inflammatory Diseases ◽  
Therapeutic Agents ◽  
Chemical Components ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Lead Compounds ◽  
National University ◽  
Botanical Characteristics ◽  
Prevention Of Cancer ◽  
Insect Repellant

Pereskia bleo, a leafy cactus, is a medicinal plant native to West and South America and distributed in tropical and subtropical areas. It is traditionally used as a dietary vegetable, barrier hedge, water purifier, and insect repellant and for maintaining health, detoxification, prevention of cancer, and/or treatment of cancer, hypertension, diabetes, stomach ache, muscle pain, and inflammatory diseases such as dermatitis and rheumatism. The aim of this paper was to provide an up-to-date and comprehensive review of the botanical characteristics, traditional usage, phytochemistry, pharmacological activities, and safety ofP. bleo. A literature search using MEDLINE (via PubMed), Science direct, Scopus and Google scholar and China Academic Journals Full-Text Database (CNKI) and available eBooks and books in the National University of Singapore libraries in English and Chinese was conducted. The following keywords were used:Pereskia bleo, Pereskia panamensis, Pereskia corrugata, Rhodocacus corrugatus, Rhodocacus bleo, Cactus panamensis, Cactus bleo, Spinach cactus, wax rose, Perescia, and Chinese rose. This review revealed the association between the traditional usage ofP. bleoand reported pharmacological properties in the literature. Further investigation on the pharmacological properties and phytoconstituents ofP. bleois warranted to further exploit its potentials as a source of novel therapeutic agents or lead compounds.

scholarly journals ETHNOBOTANICAL AND PHYTOPHARMACOLOGICAL REVIEW OF PISONIA ALBA SPAN

2017 ◽  
Vol 10 (5) ◽  
pp. 69
Author(s):  
Tamizhazhagan V ◽  
K Pugazhendy
Keyword(s):  
Traditional Medicine ◽  
Chronic Diseases ◽  
Pharmacological Properties ◽  
Medicine Use ◽  
Long Period ◽  
Toxicity Studies ◽  
Whole Plant ◽  
Novel Drug ◽  
Anti Inflammation

Pisonia alba is used for the long period in various chronic diseases in traditional medicine use. To desire of this review is to search literature for the pharmacological properties toxicity studies, pharmacology studies and phytochemical exploration of anti-inflammation, antidiabetic studies,antioxidant, etc., and the amassed data may be helpful for the researchers to attention on the significance areas of research yet to be revealed. Widespread information about the plant has been together from various books, journals and ayurvedic classical texts, etc. Researcher and pharmacologist and Ayurveda treatment may be helpful security of the whole plant was settled in the criticism.Keywords: Pisonia alba, Antioxidant, Ayurvedic, Novel drug, Ethno botanical.  

Fernandoa adenophylla: A review of its phytochemistry, traditional and pharmacology use and future aspects

2020 ◽  
Vol 06 ◽  
Author(s):  
Anushma Chorsiya ◽  
Manju Vyas Singh ◽  
Shaik Khasimbi
Keyword(s):  
Medicinal Plants ◽  
Traditional Medicine ◽  
Ursolic Acid ◽  
Oleanolic Acid ◽  
Crude Extract ◽  
Skin Disorder ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
The Future

Abstract: Fernandoa adenophylla (Heterophragma adenophyllum), commonly known as Dhopa-phali, Ziron, Mostanphul, Lotum-poh and Karen wood of family Bignoniaceae, has been used traditionally for snakebite (Morigaon district of Assam, India), hemorrhoids and constipation (Chakma tribe, Bangladesh) and skin disorder (Thai traditional medicine). This review covers pharmacognostic, phytochemical, and pharmacological as well as the traditional aspect of the plant and enlightens possible pharmacological activities Received: that can be assessed in the future. Fernandoa adenophylla has been reported to constitute potent phytochemicals like novel napthaquinones, their derivatives (dilapachone, adenophyllone, peshwaraquinone, lapachol, and indadone) and triterpenoids (β-sitosterol, β-amyrin, ursolic acid, and oleanolic acid) which have potential pharmacological activities assessed and reported. The Crude extract of Fernandoa adenophylla has already been tested for pharmacological properties like antimicrobial, antifungal, anti-TB, and antihypertensive and leishmanicidal activities. Since not many researches have been carried out on Fernandoa adenophylla, it paves way for researchers to explore its potential in the field of medicinal plants

scholarly journals A Review on Preparation of Betulinic Acid and Its Biological Activities

Molecules ◽  
2021 ◽  
Vol 26 (18) ◽  
pp. 5583
Author(s):  
Hanghang Lou ◽  
Hao Li ◽  
Shengliang Zhang ◽  
Hongyun Lu ◽  
Qihe Chen
Keyword(s):  
Betulinic Acid ◽  
Biological Activities ◽  
Wide Spectrum ◽  
Pharmacological Properties ◽  
Biosynthetic Pathways ◽  
Antitumor Effects ◽  
Pharmacological Activities ◽  
Pentacyclic Triterpene ◽  
Plane Trees ◽  
Anti Hiv

Betulinic acid, a pentacyclic triterpene, is distributed in a variety of plants, such as birch, eucalyptus and plane trees. It shows a wide spectrum of biological and pharmacological properties, such as anti-inflammatory, antibacterial, antiviral, antidiabetic, antimalarial, anti-HIV and antitumor effects. Among them, the antitumor activity of betulinic acid has been extensively studied. However, obtaining betulinic acid from natural resources can no longer meet the needs of medicine and nutrition, so methods such as chemical synthesis and microbial biotransformation have also been used to prepare betulinic acid. At the same time, with the development of synthetic biology and genetic engineering, and the elucidation of the biosynthetic pathways of terpenoid, the biosynthesis of betulinic acid has also been extensively researched. This article reviews the preparation of betulinic acid and its pharmacological activities, in order to provide a reference for the research and utilization of betulinic acid.

Exploring the Chemistry and Therapeutic Potential of Triazoles: A Comprehensive Literature Review

2019 ◽  
Vol 19 (16) ◽  
pp. 1298-1368 ◽  
Author(s):  
Ankit Jain ◽  
Poonam Piplani
Keyword(s):  
Oxidative Stress ◽  
Drug Discovery ◽  
Literature Review ◽  
Structural Modification ◽  
Therapeutic Potential ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Triazole Derivatives ◽  
Comprehensive Literature Review ◽  
The Common

: Triazole is a valuable platform in medicinal chemistry, possessing assorted pharmacological properties, which could play a major role in the common mechanisms associated with various disorders like cancer, infections, inflammation, convulsions, oxidative stress and neurodegeneration. Structural modification of this scaffold could be helpful in the generation of new therapeutically useful agents. Although research endeavors are moving towards the growth of synthetic analogs of triazole, there is still a lot of scope to achieve drug discovery break-through in this area. Upcoming therapeutic prospective of this moiety has captured the attention of medicinal chemists to synthesize novel triazole derivatives. The authors amalgamated the chemistry, synthetic strategies and detailed pharmacological activities of the triazole nucleus in the present review. Information regarding the marketed triazole derivatives has also been incorporated. The objective of the review is to provide insights to designing and synthesizing novel triazole derivatives with advanced and unexplored pharmacological implications.

Chemical Constituents and Antibacterial Activity of Cissus Aralioides.

2020 ◽  
Vol 17 ◽  
Author(s):  
Balogun Olaoye Solomon ◽  
Ajayi Olukayode Solomon ◽  
Owolabi Temitayo Abidemi ◽  
Oladimeji Abdulkarbir Oladele ◽  
Liu Zhiqiang
Keyword(s):  
Plant Extract ◽  
Chemical Constituents ◽  
Ethyl Acetate Fraction ◽  
Antibacterial Activities ◽  
Sub Saharan Africa ◽  
Chromatographic Purification ◽  
Whole Plant ◽  
Sub Saharan ◽  
First Time

: Cissus aralioides is a medicinal plant used in sub-Saharan Africa for treatment of infectious diseases; however the chemical constituents of the plant have not been investigated. Thus, in this study, attempt was made at identifying predominant phytochemical constituents of the plant through chromatographic purification and silylation of the plant extract, and subsequent characterization using spectroscopic and GC-MS techniques. The minimum inhibitory concentration (MICs) for the antibacterial activities of the plant extract, chromatographic fractions and isolated compounds were also examined. Chromatographic purification of the ethyl acetate fraction from the whole plant afforded three compounds: β-sitosterol (1), stigmasterol (2) and friedelin (3). The phytosterols (1 and 2) were obtained together as a mixture. The GC-MS analysis of silylated extract indicated alcohols, fatty acids and sugars as predominant classes, with composition of 24.62, 36.90 and 26.52% respectively. Results of MICs indicated that friedelin and other chromatographic fractions had values (0.0626-1.0 mg/mL) comparable with the standard antibiotics used. Characterization of natural products from C. aralioides is being reported for the first time in this study.

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