scholarly journals Femoral neck and spine bone mineral density-Surrogate marker of aortic calcification in postmenopausal women

Author(s):  
Petar Avramovski ◽  
Maja Avramovska ◽  
Miroslav Lazarevski ◽  
Aleksandar Sikole
2008 ◽  
Vol 31 (6) ◽  
pp. 1191-1197 ◽  
Author(s):  
Hiroyuki SUMINO ◽  
Shuichi ICHIKAWA ◽  
Shu KASAMA ◽  
Takashi TAKAHASHI ◽  
Hironosuke SAKAMOTO ◽  
...  

2022 ◽  
Author(s):  
Lizhi Zhang ◽  
Jinwei He ◽  
Xiang Sun ◽  
Dongyue Pang ◽  
Jingjing Hu ◽  
...  

Our previous studies have demonstrated that there is a correlation between GLP-1R SNP and the BMD in postmenopausal women. GLP-1 and GIP are both incretins. Whether the mutation of GIPR gene affects bone metabolism. SNP rs10423928 is a GIPR gene polymorphism that has been studied more frequently. The aim of this study was to investigate the association between GIPR SNP rs10423928 and bone-mineral density (BMD) in postmenopausal women in Shanghai. The GIPR SNP rs10423928 was detected in 884 postmenopausal women in Shanghai, the correlation between the GIPR SNP and BMD was further assessed. The dominant T/T genotype of the GIPR SNP rs10423928 was significantly related to BMD of the femoral neck (P = 0.035) and Ward’s triangle area (P = 0.033). Our research found that the dominant T/T genotype of GIPR SNP rs10423928 in postmenopausal women is significantly associated with higher BMD. The T/T genotype seems to have bone protection.


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