The Role of Biomarkers in the Diagnosis of Patent Ductus Arteriosus

2013 ◽  
Vol 5 (3) ◽  
pp. 97-101
Author(s):  
Istemi Han Celik ◽  
Omer Erdeve
Keyword(s):  
Patent Ductus Arteriosus ◽  
Ductus Arteriosus ◽  
Patent Ductus

scholarly journals Comparison of the effect of two drugs paracetamol with intravenous ibuprofen in patent ductus arteriosus treatment

2020 ◽  
Vol 9 (5) ◽  
pp. 690
Author(s):  
Mehrdad Mirzarahimi ◽  
Ramin Emamzadeghan ◽  
Afsaneh Enteshari Moghaddam ◽  
Narges Falsafi
Keyword(s):  
Patent Ductus Arteriosus ◽  
Ductus Arteriosus ◽  
Alternative Therapy ◽  
Cyclooxygenase Inhibitors ◽  
Arterial Duct ◽  
Intravenous Paracetamol ◽  
Liver Parameters ◽  
Intravenous Ibuprofen ◽  
Patent Ductus

Background: Patent ductus arteriosus (PDA) is a common cause of morbidity and mortality among premature infants that affects more than 40% of them. PDA treatment includes medical and surgical treatment. Most drugs used to block PDA are cyclooxygenase inhibitors (ibuprofen and indomethacin). The role of paracetamol as an alternative therapy in PDA ligation has been considered in recent years due to the potential side effects of cyclooxygenase inhibitors.Methods: Patients in the first group were treated with intravenous paracetamol at a dose of 15 mg/kg every 6 hours for three days and the second group was treated with intravenous ibuprofen at a daily dose of 10 mg/kg daily and 5 mg/kg for the second and third days. At the end of the treatment period (day 3), they underwent echocardiography again. If the echocardiographic findings indicated no closure of the arterial duct, patients were treated with the aforementioned drug for another period and rechecked at the end of the third day, and at each stage required information was collected.Results: Arterial duct closure in paracetamol group was 96.7% and in ibuprofen group was 100%. The effects of both paracetamol and ibuprofen were similar in terms of renal parameters but in terms of effects on liver parameters. The effect of paracetamol on all liver parameters except aspartate transaminase (AST) was significant, but ibuprofen was able to affect only bilirubin among liver parameters and had no significant effect on both AST and alanine aminotransferase, parameters.Conclusions: Results showed that both paracetamol and ibuprofen are effective in treating of PDA and had similar impact.

Role of Transcatheter patent ductus arteriosus closure in extremely low birth weight infants

2018 ◽  
Vol 93 (1) ◽  
pp. 89-96 ◽  
Author(s):  
Shyam Sathanandam ◽  
Kaitlin Balduf ◽  
Sandeep Chilakala ◽  
Kristen Washington ◽  
Kimberly Allen ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Patent Ductus Arteriosus ◽  
Ductus Arteriosus ◽  
Extremely Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Patent Ductus Arteriosus Closure ◽  
Patent Ductus

scholarly journals The Patent Ductus Arteriosus in Adults with Special Focus on Role of CT

Diagnostics ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 2394
Author(s):  
Soo Jeong Lee ◽  
Seung Min Yoo ◽  
Min Ji Son ◽  
Charles S. White
Keyword(s):  
Patent Ductus Arteriosus ◽  
Imaging Modality ◽  
Ductus Arteriosus ◽  
High Rate ◽  
Special Focus ◽  
Clinical Perspective ◽  
Occluder Device ◽  
Missed Diagnosis ◽  
Patent Ductus

The primary imaging modality for the diagnosis of patent ductus arteriosus (PDA) is echocardiography. However, CT may be the technique on which an incidental PDA is first recognized because of the increasing number of chest CT scans performed for a variety of causes. Identification of PDA on CT may lead to earlier closure using a PDA occluder device. Immediate identification of incidental PDA is important, but a high rate of missed diagnosis of PDA has been reported due to its small size and anatomic location. In addition, echocardiography may overlook the presence of even a large PDA due to decrease in the amount of shunting through the PDA caused by high pulmonary artery pressures. This review provides the basic CT anatomy and clinical perspective of PDA, and discusses the role of CT in the evaluation of PDA as well as methods to avoid overlooking a small PDA on CT.

Early Role of the Atrial-Level Communication in Premature Infants with Patent Ductus Arteriosus

2020 ◽  
Author(s):  
Danielle R. Rios ◽  
Fernando de Freitas Martins ◽  
Afif El-Khuffash ◽  
Dany E. Weisz ◽  
Regan E. Giesinger ◽  
...  
Keyword(s):  
Patent Ductus Arteriosus ◽  
Premature Infants ◽  
Ductus Arteriosus ◽  
Patent Ductus

Variable role of patent ductus arteriosus

2018 ◽  
Vol 23 (4) ◽  
pp. 273-277 ◽  
Author(s):  
Jennifer Shepherd ◽  
Kai-Hsiang Hsu ◽  
Shahab Noori
Keyword(s):  
Patent Ductus Arteriosus ◽  
Ductus Arteriosus ◽  
Patent Ductus
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